(21 nodes) Phosphatidylinositol 3-kinase signaling network (Anas platyrhynchos)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	C1QBP	Complement C1q binding protein. (162 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	U3I9N3_ANAPP	Uncharacterized protein. (511 aa)
	PPARD	Peroxisome proliferator activated receptor delta. (381 aa)
	PIK3CG	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
	KBTBD2	Kelch repeat and BTB domain containing 2. (623 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
	NYAP2	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2. (715 aa)
	PIK3C2G	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1476 aa)
	PLEKHA1	Pleckstrin homology domain containing A1. (411 aa)
	GATA3	GATA binding protein 3. (712 aa)
	PIK3C2A	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1700 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (471 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PRR5	Proline rich 5. (413 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (463 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	EDN1	Endothelin 1. (203 aa)
	PIK3C2B	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (681 aa)
	PRR5L	Proline rich 5 like. (366 aa)
	ENSAPLP00000023272	SERPIN domain-containing protein; Belongs to the serpin family. (484 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HTR2A	HTR2B	ENSAPLP00000011416	ENSAPLP00000015027	5-hydroxytryptamine receptor 2A.	5-hydroxytryptamine receptor 2B.	0.962
HTR2B	HTR2A	ENSAPLP00000015027	ENSAPLP00000011416	5-hydroxytryptamine receptor 2B.	5-hydroxytryptamine receptor 2A.	0.962
PIK3C2A	PIK3C2B	ENSAPLP00000010610	ENSAPLP00000020566	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	0.910
PIK3C2A	PIK3C2G	ENSAPLP00000010610	ENSAPLP00000009675	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.	0.987
PIK3C2A	PTEN	ENSAPLP00000010610	ENSAPLP00000015564	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.920
PIK3C2B	PIK3C2A	ENSAPLP00000020566	ENSAPLP00000010610	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	0.910
PIK3C2B	PIK3C2G	ENSAPLP00000020566	ENSAPLP00000009675	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.	0.910
PIK3C2B	PIK3CB	ENSAPLP00000020566	ENSAPLP00000003138	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.410
PIK3C2B	PIK3CD	ENSAPLP00000020566	ENSAPLP00000007963	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.555
PIK3C2B	PIK3CG	ENSAPLP00000020566	ENSAPLP00000006296	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.746
PIK3C2B	PTEN	ENSAPLP00000020566	ENSAPLP00000015564	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.920
PIK3C2G	PIK3C2A	ENSAPLP00000009675	ENSAPLP00000010610	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	0.987
PIK3C2G	PIK3C2B	ENSAPLP00000009675	ENSAPLP00000020566	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	0.910
PIK3C2G	PTEN	ENSAPLP00000009675	ENSAPLP00000015564	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.920
PIK3CA	PIK3CB	ENSAPLP00000012758	ENSAPLP00000003138	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.973
PIK3CA	PIK3CD	ENSAPLP00000012758	ENSAPLP00000007963	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.973
PIK3CA	PIK3CG	ENSAPLP00000012758	ENSAPLP00000006296	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.838
PIK3CA	PTEN	ENSAPLP00000012758	ENSAPLP00000015564	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.979
PIK3CA	U3I9N3_ANAPP	ENSAPLP00000012758	ENSAPLP00000003954	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein.	0.441
PIK3CB	PIK3C2B	ENSAPLP00000003138	ENSAPLP00000020566	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family.	0.410