(29 nodes) Cytosolic small ribosomal subunit network (Anas platyrhynchos)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Your Input:
	RPS27L	40S ribosomal protein S27. (84 aa)
	RPS21	Ribosomal protein S21. (84 aa)
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (297 aa)
	EIF2A	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (578 aa)
	RPS23	Ribosomal protein S23. (211 aa)
	RPS15	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (158 aa)
	RPS10	Ribosomal protein S10. (196 aa)
	RPS5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (276 aa)
	RPS25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (93 aa)
	ENSAPLP00000026123	Uncharacterized protein. (192 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	ENSAPLP00000022443	Ribosomal_S4 domain-containing protein. (96 aa)
	RPS19	Uncharacterized protein. (88 aa)
	RPS6	Uncharacterized protein. (492 aa)
	RPS16	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	EIF2D	Eukaryotic translation initiation factor 2D. (599 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	RPS14	Ribosomal protein S14. (154 aa)
	MRPS11	Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (175 aa)
	RPS13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	DHX29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1209 aa)
	RPS8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (213 aa)
	RPS12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	RPS2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (286 aa)
	RPS4X	Ribosomal protein S4 X-linked. (324 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	RPS3A	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (264 aa)
	RPS7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	RPS28	Ribosomal protein S28. (69 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHX29	EIF2D	ENSAPLP00000008898	ENSAPLP00000014714	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 2D.	0.500
DHX29	ENSAPLP00000022443	ENSAPLP00000008898	ENSAPLP00000022443	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal_S4 domain-containing protein.	0.440
DHX29	RPS10	ENSAPLP00000008898	ENSAPLP00000029768	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S10.	0.420
DHX29	RPS12	ENSAPLP00000008898	ENSAPLP00000008212	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.	0.455
DHX29	RPS13	ENSAPLP00000008898	ENSAPLP00000011766	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.497
DHX29	RPS14	ENSAPLP00000008898	ENSAPLP00000013737	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S14.	0.578
DHX29	RPS16	ENSAPLP00000008898	ENSAPLP00000015793	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.	0.517
DHX29	RPS19	ENSAPLP00000008898	ENSAPLP00000019464	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Uncharacterized protein.	0.510
DHX29	RPS2	ENSAPLP00000008898	ENSAPLP00000008154	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.576
DHX29	RPS23	ENSAPLP00000008898	ENSAPLP00000030284	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S23.	0.496
DHX29	RPS27A	ENSAPLP00000008898	ENSAPLP00000004982	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ubiquitin-like domain-containing protein.	0.572
DHX29	RPS28	ENSAPLP00000008898	ENSAPLP00000000325	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S28.	0.561
DHX29	RPS3	ENSAPLP00000008898	ENSAPLP00000014372	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.441
DHX29	RPS3A	ENSAPLP00000008898	ENSAPLP00000002877	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family.	0.560
DHX29	RPS5	ENSAPLP00000008898	ENSAPLP00000028675	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.	0.552
DHX29	RPS6	ENSAPLP00000008898	ENSAPLP00000018457	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Uncharacterized protein.	0.476
DHX29	RPS7	ENSAPLP00000008898	ENSAPLP00000001900	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	0.649
DHX29	RPS8	ENSAPLP00000008898	ENSAPLP00000008818	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family.	0.560
DHX29	RPSA	ENSAPLP00000008898	ENSAPLP00000031689	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	0.493
EIF2D	DHX29	ENSAPLP00000014714	ENSAPLP00000008898	Eukaryotic translation initiation factor 2D.	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	0.500