(12 nodes) SUMO binding network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOBP	Sine oculis binding protein homolog. (873 aa)
	CASP8AP2	Caspase 8 associated protein 2. (2019 aa)
	USPL1	Ubiquitin specific peptidase like 1. (1088 aa)
	RNF4	Ring finger protein 4. (192 aa)
	SIMC1	SUMO interacting motifs containing 1. (856 aa)
	UBA2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (541 aa)
	SERBP1	SERPINE1 mRNA binding protein 1. (656 aa)
	TDG	Thymine DNA glycosylase. (296 aa)
	ENSAPLP00000024647	Uncharacterized protein. (520 aa)
	CBX7	Chromobox 7. (251 aa)
	CBX4	Chromobox 4. (491 aa)
	ENSAPLP00000030796	Uncharacterized protein. (1090 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP8AP2	CBX4	ENSAPLP00000001718	ENSAPLP00000029872	Caspase 8 associated protein 2.	Chromobox 4.	0.405
CBX4	CASP8AP2	ENSAPLP00000029872	ENSAPLP00000001718	Chromobox 4.	Caspase 8 associated protein 2.	0.405
CBX4	CBX7	ENSAPLP00000029872	ENSAPLP00000028508	Chromobox 4.	Chromobox 7.	0.695
CBX7	CBX4	ENSAPLP00000028508	ENSAPLP00000029872	Chromobox 7.	Chromobox 4.	0.695
ENSAPLP00000024647	RNF4	ENSAPLP00000024647	ENSAPLP00000004802	Uncharacterized protein.	Ring finger protein 4.	0.599
ENSAPLP00000030796	RNF4	ENSAPLP00000030796	ENSAPLP00000004802	Uncharacterized protein.	Ring finger protein 4.	0.612
RNF4	ENSAPLP00000024647	ENSAPLP00000004802	ENSAPLP00000024647	Ring finger protein 4.	Uncharacterized protein.	0.599
RNF4	ENSAPLP00000030796	ENSAPLP00000004802	ENSAPLP00000030796	Ring finger protein 4.	Uncharacterized protein.	0.612
RNF4	UBA2	ENSAPLP00000004802	ENSAPLP00000010917	Ring finger protein 4.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.490
UBA2	RNF4	ENSAPLP00000010917	ENSAPLP00000004802	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ring finger protein 4.	0.490