(17 nodes) Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway network (Anas platyrhynchos)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VPS25	Uncharacterized protein. (140 aa)
	VPS37C	VPS37C subunit of ESCRT-I. (388 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (441 aa)
	CHMP5	Charged multivesicular body protein 5. (219 aa)
	VPS37A	VPS37A subunit of ESCRT-I. (399 aa)
	STAM	Signal transducing adaptor molecule. (526 aa)
	PLAA	Phospholipase A2 activating protein. (884 aa)
	VPS37D	VPS37D subunit of ESCRT-I. (423 aa)
	UBAP1	Ubiquitin associated protein 1. (521 aa)
	SNF8	SNF8 subunit of ESCRT-II. (223 aa)
	UBAP1L	Ubiquitin associated protein 1 like. (429 aa)
	RNF115	Ring finger protein 115. (250 aa)
	U3HZV8_ANAPP	Uncharacterized protein. (218 aa)
	VPS36	Vacuolar protein sorting 36 homolog. (386 aa)
	VPS37B	VPS37B subunit of ESCRT-I. (286 aa)
	RNF126	Ring finger protein 126. (336 aa)
	ENSAPLP00000029894	Uncharacterized protein; Belongs to the AAA ATPase family. (529 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHMP5	ENSAPLP00000029894	ENSAPLP00000007816	ENSAPLP00000029894	Charged multivesicular body protein 5.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.952
CHMP5	SNF8	ENSAPLP00000007816	ENSAPLP00000021482	Charged multivesicular body protein 5.	SNF8 subunit of ESCRT-II.	0.428
CHMP5	STAM	ENSAPLP00000007816	ENSAPLP00000010731	Charged multivesicular body protein 5.	Signal transducing adaptor molecule.	0.614
CHMP5	U3HZV8_ANAPP	ENSAPLP00000007816	ENSAPLP00000000528	Charged multivesicular body protein 5.	Uncharacterized protein.	0.931
CHMP5	VPS25	ENSAPLP00000007816	ENSAPLP00000030714	Charged multivesicular body protein 5.	Uncharacterized protein.	0.589
CHMP5	VPS36	ENSAPLP00000007816	ENSAPLP00000004534	Charged multivesicular body protein 5.	Vacuolar protein sorting 36 homolog.	0.589
CHMP5	VPS37A	ENSAPLP00000007816	ENSAPLP00000010725	Charged multivesicular body protein 5.	VPS37A subunit of ESCRT-I.	0.482
CHMP5	VPS37B	ENSAPLP00000007816	ENSAPLP00000025455	Charged multivesicular body protein 5.	VPS37B subunit of ESCRT-I.	0.653
CHMP5	VPS4B	ENSAPLP00000007816	ENSAPLP00000006235	Charged multivesicular body protein 5.	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.	0.952
ENSAPLP00000029894	CHMP5	ENSAPLP00000029894	ENSAPLP00000007816	Uncharacterized protein; Belongs to the AAA ATPase family.	Charged multivesicular body protein 5.	0.952
ENSAPLP00000029894	SNF8	ENSAPLP00000029894	ENSAPLP00000021482	Uncharacterized protein; Belongs to the AAA ATPase family.	SNF8 subunit of ESCRT-II.	0.609
ENSAPLP00000029894	U3HZV8_ANAPP	ENSAPLP00000029894	ENSAPLP00000000528	Uncharacterized protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.874
ENSAPLP00000029894	VPS25	ENSAPLP00000029894	ENSAPLP00000030714	Uncharacterized protein; Belongs to the AAA ATPase family.	Uncharacterized protein.	0.503
ENSAPLP00000029894	VPS36	ENSAPLP00000029894	ENSAPLP00000004534	Uncharacterized protein; Belongs to the AAA ATPase family.	Vacuolar protein sorting 36 homolog.	0.522
ENSAPLP00000029894	VPS37C	ENSAPLP00000029894	ENSAPLP00000028502	Uncharacterized protein; Belongs to the AAA ATPase family.	VPS37C subunit of ESCRT-I.	0.635
ENSAPLP00000029894	VPS4B	ENSAPLP00000029894	ENSAPLP00000006235	Uncharacterized protein; Belongs to the AAA ATPase family.	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family.	0.881
PLAA	STAM	ENSAPLP00000014083	ENSAPLP00000010731	Phospholipase A2 activating protein.	Signal transducing adaptor molecule.	0.440
SNF8	CHMP5	ENSAPLP00000021482	ENSAPLP00000007816	SNF8 subunit of ESCRT-II.	Charged multivesicular body protein 5.	0.428
SNF8	ENSAPLP00000029894	ENSAPLP00000021482	ENSAPLP00000029894	SNF8 subunit of ESCRT-II.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.609
SNF8	STAM	ENSAPLP00000021482	ENSAPLP00000010731	SNF8 subunit of ESCRT-II.	Signal transducing adaptor molecule.	0.815