(14 nodes) Negative regulation of potassium ion transport network (Anas platyrhynchos)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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co-expression

protein homology

Your Input:
	KCNE1	Uncharacterized protein. (126 aa)
	KCNE2	Potassium voltage-gated channel subfamily E regulatory subunit 2. (125 aa)
	ATF4	Activating transcription factor 4. (354 aa)
	KCNE4	Potassium voltage-gated channel subfamily E regulatory subunit 4. (180 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	U3I882_ANAPP	Protein kinase domain-containing protein. (355 aa)
	U3ID42_ANAPP	Uncharacterized protein. (718 aa)
	VIP	Vasoactive intestinal peptide. (200 aa)
	STK39	Serine/threonine kinase 39. (480 aa)
	KCNE5	Potassium voltage-gated channel subfamily E regulatory subunit 5. (111 aa)
	KCNRG	Potassium channel regulator. (305 aa)
	KCNAB2	Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (431 aa)
	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (206 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAV1	CAV3	ENSAPLP00000001402	ENSAPLP00000002546	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.930
CAV3	CAV1	ENSAPLP00000002546	ENSAPLP00000001402	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.930
KCNAB1	KCNRG	ENSAPLP00000028180	ENSAPLP00000019757	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	Potassium channel regulator.	0.414
KCNAB2	KCNRG	ENSAPLP00000020657	ENSAPLP00000019757	Potassium voltage-gated channel subfamily A regulatory beta subunit 2.	Potassium channel regulator.	0.414
KCNE1	KCNE4	ENSAPLP00000000626	ENSAPLP00000001231	Uncharacterized protein.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.429
KCNE1	KCNE5	ENSAPLP00000000626	ENSAPLP00000012158	Uncharacterized protein.	Potassium voltage-gated channel subfamily E regulatory subunit 5.	0.434
KCNE2	KCNE4	ENSAPLP00000000635	ENSAPLP00000001231	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.497
KCNE2	KCNE5	ENSAPLP00000000635	ENSAPLP00000012158	Potassium voltage-gated channel subfamily E regulatory subunit 2.	Potassium voltage-gated channel subfamily E regulatory subunit 5.	0.474
KCNE4	KCNE1	ENSAPLP00000001231	ENSAPLP00000000626	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Uncharacterized protein.	0.429
KCNE4	KCNE2	ENSAPLP00000001231	ENSAPLP00000000635	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.497
KCNE4	KCNE5	ENSAPLP00000001231	ENSAPLP00000012158	Potassium voltage-gated channel subfamily E regulatory subunit 4.	Potassium voltage-gated channel subfamily E regulatory subunit 5.	0.482
KCNE5	KCNE1	ENSAPLP00000012158	ENSAPLP00000000626	Potassium voltage-gated channel subfamily E regulatory subunit 5.	Uncharacterized protein.	0.434
KCNE5	KCNE2	ENSAPLP00000012158	ENSAPLP00000000635	Potassium voltage-gated channel subfamily E regulatory subunit 5.	Potassium voltage-gated channel subfamily E regulatory subunit 2.	0.474
KCNE5	KCNE4	ENSAPLP00000012158	ENSAPLP00000001231	Potassium voltage-gated channel subfamily E regulatory subunit 5.	Potassium voltage-gated channel subfamily E regulatory subunit 4.	0.482
KCNRG	KCNAB1	ENSAPLP00000019757	ENSAPLP00000028180	Potassium channel regulator.	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1.	0.414
KCNRG	KCNAB2	ENSAPLP00000019757	ENSAPLP00000020657	Potassium channel regulator.	Potassium voltage-gated channel subfamily A regulatory beta subunit 2.	0.414