STRINGSTRING
PPARGC1A PPARGC1A UBOX5 UBOX5 SMC6 SMC6 CUL3 CUL3 FZD5 FZD5 FZD4 FZD4 DET1 DET1 ENSAPLP00000031150 ENSAPLP00000031150 XBP1 XBP1 ENSAPLP00000030796 ENSAPLP00000030796 TMBIM6 TMBIM6 MFHAS1 MFHAS1 PRR7 PRR7 FZD8 FZD8 TRIP4 TRIP4 SLF1 SLF1 ENSAPLP00000029661 ENSAPLP00000029661 OTUB1 OTUB1 ENSAPLP00000029099 ENSAPLP00000029099 ENSAPLP00000029003 ENSAPLP00000029003 ERLIN2 ERLIN2 TRAF3 TRAF3 FHIT FHIT SQSTM1 SQSTM1 ENSAPLP00000028223 ENSAPLP00000028223 TRAF6 TRAF6 ENSAPLP00000027889 ENSAPLP00000027889 TRAF1 TRAF1 HM13 HM13 ANKRA2 ANKRA2 ENSAPLP00000027532 ENSAPLP00000027532 UBE2C UBE2C UBE2A UBE2A TRIM37 TRIM37 BRCA1 BRCA1 RALA RALA RALB RALB MUL1 MUL1 PRKN PRKN DERL1 DERL1 SNCAIP SNCAIP ENSAPLP00000025536 ENSAPLP00000025536 FBXW7 FBXW7 ENSAPLP00000025095 ENSAPLP00000025095 GABARAPL1 GABARAPL1 ENSAPLP00000024647 ENSAPLP00000024647 DNM1L DNM1L UBXN7 UBXN7 ENSAPLP00000024412 ENSAPLP00000024412 ENSAPLP00000024303 ENSAPLP00000024303 TRAF2 TRAF2 RRP8 RRP8 ENSAPLP00000024056 ENSAPLP00000024056 GABARAPL2 GABARAPL2 ENSAPLP00000023897 ENSAPLP00000023897 GLMN GLMN ENSAPLP00000023149 ENSAPLP00000023149 ENSAPLP00000022825 ENSAPLP00000022825 SCAMP3 SCAMP3 SUMO1 SUMO1 CDK5RAP3 CDK5RAP3 NGFR NGFR CEBPB CEBPB PRR5L PRR5L ENSAPLP00000021642 ENSAPLP00000021642 CUL4A CUL4A CACYBP CACYBP CUL1 CUL1 ASB4 ASB4 ENSAPLP00000020785 ENSAPLP00000020785 ENSAPLP00000020702 ENSAPLP00000020702 DTX3L DTX3L UBE2G1 UBE2G1 CUL4B CUL4B SPOP SPOP SNX9 SNX9 BCL2 BCL2 ENSAPLP00000019451 ENSAPLP00000019451 ENSAPLP00000019203 ENSAPLP00000019203 SHPRH SHPRH SPART SPART MAP1LC3B MAP1LC3B TRAF4 TRAF4 WBP1L WBP1L CUL2 CUL2 RTN1 RTN1 MAP1LC3C MAP1LC3C HSPD1 HSPD1 ENSAPLP00000016691 ENSAPLP00000016691 CD40 CD40 FANCL FANCL UBE2T UBE2T PRKACB PRKACB ABI2 ABI2 ARIH1 ARIH1 RPL5 RPL5 UBE2J1 UBE2J1 PSMA3 PSMA3 AMBRA1 AMBRA1 RIPK1 RIPK1 CASP10 CASP10 U3J6D9_ANAPP U3J6D9_ANAPP DBT DBT DDX58 DDX58 CUL5 CUL5 CASP8 CASP8 UBE2B UBE2B RNF8 RNF8 SYT11 SYT11 SLC22A18 SLC22A18 ARRDC1 ARRDC1 TRIB1 TRIB1 MAP1LC3A MAP1LC3A ATF6 ATF6 AICDA AICDA LAPTM4B LAPTM4B CAMLG CAMLG U3J1S1_ANAPP U3J1S1_ANAPP U3J1P7_ANAPP U3J1P7_ANAPP ITCH ITCH CCT2 CCT2 TRIB2 TRIB2 WFS1 WFS1 XRCC5 XRCC5 HGS HGS ERLIN1 ERLIN1 MFN2 MFN2 UBE2K UBE2K USP13 USP13 UBASH3B UBASH3B AXIN2 AXIN2 STAM STAM PIAS4 PIAS4 FBXO7 FBXO7 U3ISG8_ANAPP U3ISG8_ANAPP SMG5 SMG5 PARP9 PARP9 PACRG PACRG GPI GPI VCL VCL STX8 STX8 SKI SKI PACRGL PACRGL CHEK2 CHEK2 FAF2 FAF2 LAPTM5 LAPTM5 LRPPRC LRPPRC SPOPL SPOPL BID BID PRKAR1A PRKAR1A UBASH3A UBASH3A TANK TANK PRKAR1B PRKAR1B RB1 RB1 USP19 USP19 PINK1 PINK1 BLZF1 BLZF1 PRKAR2B PRKAR2B RANGAP1 RANGAP1 SUMO2 SUMO2 TRAF5 TRAF5 CACUL1 CACUL1 PRKAR2A PRKAR2A AXIN1 AXIN1 LYN LYN U3IEG1_ANAPP U3IEG1_ANAPP RTN4 RTN4 MYOD1 MYOD1 TXNIP TXNIP RPS27A RPS27A PIAS2 PIAS2 FAM162A FAM162A UBE2L3 UBE2L3 AUP1 AUP1 JKAMP JKAMP RNF34 RNF34 SLF2 SLF2 TPI1 TPI1 BAG2 BAG2 BCL10 BCL10 HSPA5 HSPA5 UBE2J2 UBE2J2 RAD18 RAD18 FAF1 FAF1 NLK NLK YWHAZ YWHAZ ANAPC2 ANAPC2 BAG5 BAG5 YOD1 YOD1 U3I1L7_ANAPP U3I1L7_ANAPP MC4R MC4R SMAD7 SMAD7 SMAD6 SMAD6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPARGC1APPARG coactivator 1 alpha. (834 aa)
UBOX5U-box domain containing 5. (545 aa)
SMC6Structural maintenance of chromosomes 6. (1101 aa)
CUL3Cullin 3; Belongs to the cullin family. (1175 aa)
FZD5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
DET1Uncharacterized protein. (572 aa)
ENSAPLP00000031150Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (71 aa)
XBP1X-box binding protein 1. (313 aa)
ENSAPLP00000030796Uncharacterized protein. (1090 aa)
TMBIM6Transmembrane BAX inhibitor motif containing 6. (376 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1009 aa)
PRR7Proline rich 7, synaptic. (230 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (682 aa)
TRIP4Thyroid hormone receptor interactor 4. (583 aa)
SLF1SMC5-SMC6 complex localization factor 1. (940 aa)
ENSAPLP00000029661Uncharacterized protein. (317 aa)
OTUB1OTU deubiquitinase, ubiquitin aldehyde binding 1. (129 aa)
ENSAPLP00000029099Ubiquitin-like domain-containing protein. (48 aa)
ENSAPLP00000029003Uncharacterized protein. (124 aa)
ERLIN2ER lipid raft associated 2. (410 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
FHITUncharacterized protein. (74 aa)
SQSTM1Uncharacterized protein. (77 aa)
ENSAPLP00000028223PDZ domain-containing protein. (495 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
ENSAPLP00000027889Uncharacterized protein. (216 aa)
TRAF1TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
HM13Histocompatibility minor 13. (389 aa)
ANKRA2Ankyrin repeat family A member 2. (428 aa)
ENSAPLP00000027532Link domain-containing protein. (79 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (87 aa)
UBE2AUbiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (115 aa)
TRIM37Tripartite motif containing 37. (1025 aa)
BRCA1BRCA1 DNA repair associated. (1846 aa)
RALARAS like proto-oncogene A. (262 aa)
RALBRAS like proto-oncogene B. (206 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (175 aa)
PRKNParkin RBR E3 ubiquitin protein ligase. (520 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (339 aa)
SNCAIPSynuclein alpha interacting protein. (964 aa)
ENSAPLP00000025536Ubiquitin-like domain-containing protein. (138 aa)
FBXW7F-box and WD repeat domain containing 7. (754 aa)
ENSAPLP00000025095Reticulon domain-containing protein. (126 aa)
GABARAPL1GABA type A receptor associated protein like 1. (260 aa)
ENSAPLP00000024647Uncharacterized protein. (520 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (750 aa)
UBXN7UBX domain-containing protein 7. (489 aa)
ENSAPLP00000024412Death domain-containing protein. (197 aa)
ENSAPLP00000024303RING-type domain-containing protein. (385 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
RRP8Uncharacterized protein. (716 aa)
ENSAPLP00000024056SH2 domain-containing protein. (621 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
GLMNGlomulin, FKBP associated protein. (636 aa)
ENSAPLP00000023149Uncharacterized protein. (275 aa)
ENSAPLP00000022825Complex1_49kDa domain-containing protein. (276 aa)
SCAMP3Secretory carrier-associated membrane protein. (469 aa)
SUMO1Small ubiquitin like modifier 1. (242 aa)
CDK5RAP3CDK5 regulatory subunit associated protein 3. (526 aa)
NGFRUncharacterized protein. (181 aa)
CEBPBCCAAT/enhancer-binding protein. (306 aa)
PRR5LProline rich 5 like. (366 aa)
ENSAPLP00000021642Uncharacterized protein. (82 aa)
CUL4ACullin 4A; Belongs to the cullin family. (617 aa)
CACYBPCalcyclin binding protein. (237 aa)
CUL1Cullin 1; Belongs to the cullin family. (768 aa)
ASB4Ankyrin repeat and SOCS box containing 4. (435 aa)
ENSAPLP00000020785RGS domain-containing protein. (143 aa)
ENSAPLP00000020702Uncharacterized protein. (213 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (741 aa)
UBE2G1Ubiquitin conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (266 aa)
CUL4BCullin 4B; Belongs to the cullin family. (886 aa)
SPOPSpeckle type BTB/POZ protein. (392 aa)
SNX9Sorting nexin 9. (635 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ENSAPLP00000019451Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1304 aa)
ENSAPLP00000019203UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
SHPRHSNF2 histone linker PHD RING helicase. (1724 aa)
SPARTSpartin. (614 aa)
MAP1LC3BUncharacterized protein. (125 aa)
TRAF4TNF receptor-associated factor. (470 aa)
WBP1LWW domain binding protein 1 like. (433 aa)
CUL2Cullin 2; Belongs to the cullin family. (774 aa)
RTN1Reticulon. (767 aa)
MAP1LC3CMicrotubule associated protein 1 light chain 3 gamma. (142 aa)
HSPD1Heat shock protein family D (Hsp60) member 1; Belongs to the chaperonin (HSP60) family. (185 aa)
ENSAPLP00000016691Uncharacterized protein. (235 aa)
CD40TNFR-Cys domain-containing protein. (214 aa)
FANCLFA complementation group L. (373 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (373 aa)
PRKACBUncharacterized protein; Belongs to the protein kinase superfamily. (397 aa)
ABI2Abl interactor 2. (499 aa)
ARIH1RBR-type E3 ubiquitin transferase. (554 aa)
RPL5Ribosomal_L18_c domain-containing protein. (246 aa)
UBE2J1Ubiquitin conjugating enzyme E2 J1. (268 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1166 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (538 aa)
U3J6D9_ANAPPUncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
DDX58DExD/H-box helicase 58. (880 aa)
CUL5Cullin 5; Belongs to the cullin family. (780 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (466 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (150 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (612 aa)
SYT11Synaptotagmin 11. (430 aa)
SLC22A18Solute carrier family 22 member 18. (477 aa)
ARRDC1Arrestin domain containing 1. (421 aa)
TRIB1Tribbles pseudokinase 1. (364 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (116 aa)
ATF6Activating transcription factor 6. (732 aa)
AICDAActivation induced cytidine deaminase. (203 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (267 aa)
CAMLGCalcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (291 aa)
U3J1S1_ANAPPUncharacterized protein. (494 aa)
U3J1P7_ANAPPUncharacterized protein. (428 aa)
ITCHE3 ubiquitin-protein ligase. (769 aa)
CCT2Chaperonin containing TCP1 subunit 2. (581 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
WFS1Wolframin ER transmembrane glycoprotein. (874 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (725 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate. (726 aa)
ERLIN1ER lipid raft associated 1. (345 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa)
UBE2KUbiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (433 aa)
USP13Ubiquitin carboxyl-terminal hydrolase. (856 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (650 aa)
AXIN2DIX domain-containing protein. (274 aa)
STAMSignal transducing adaptor molecule. (526 aa)
PIAS4Protein inhibitor of activated STAT 4. (485 aa)
FBXO7F-box protein 7. (588 aa)
U3ISG8_ANAPPUncharacterized protein. (134 aa)
SMG5SMG5 nonsense mediated mRNA decay factor. (985 aa)
PARP9Poly [ADP-ribose] polymerase. (819 aa)
PACRGParkin coregulated. (254 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
VCLVinculin. (1135 aa)
STX8Syntaxin 8. (417 aa)
SKISKI proto-oncogene. (744 aa)
PACRGLParkin coregulated like. (226 aa)
CHEK2Checkpoint kinase 2. (524 aa)
FAF2Fas associated factor family member 2. (444 aa)
LAPTM5Lysosomal protein transmembrane 5. (258 aa)
LRPPRCUncharacterized protein. (857 aa)
SPOPLSpeckle type BTB/POZ protein like. (392 aa)
BIDBH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (193 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (382 aa)
UBASH3AUbiquitin associated and SH3 domain containing A. (626 aa)
TANKTRAF family member associated NFKB activator. (481 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
RB1RB transcriptional corepressor 1. (855 aa)
USP19Ubiquitin specific peptidase 19. (1415 aa)
PINK1PTEN induced kinase 1. (603 aa)
BLZF1Basic leucine zipper nuclear factor 1. (397 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (440 aa)
RANGAP1Ran GTPase activating protein 1. (562 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
CACUL1CDK2 associated cullin domain 1; Belongs to the cullin family. (334 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (400 aa)
AXIN1Axin 1. (841 aa)
LYNTyrosine-protein kinase. (535 aa)
U3IEG1_ANAPPJosephin domain-containing protein. (283 aa)
RTN4Reticulon. (1011 aa)
MYOD1Myogenic factor. (297 aa)
TXNIPThioredoxin interacting protein. (390 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PIAS2Protein inhibitor of activated STAT 2. (631 aa)
FAM162AFamily with sequence similarity 162 member A. (133 aa)
UBE2L3Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (412 aa)
JKAMPJNK1/MAPK8 associated membrane protein. (314 aa)
RNF34Ring finger protein 34. (346 aa)
SLF2SMC5-SMC6 complex localization factor 2. (1204 aa)
TPI1Triosephosphate isomerase. (222 aa)
BAG2BCL2 associated athanogene 2. (225 aa)
BCL10CARD domain-containing protein. (316 aa)
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (652 aa)
UBE2J2Ubiquitin conjugating enzyme E2 J2. (259 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (501 aa)
FAF1Fas associated factor 1. (650 aa)
NLKMitogen-activated protein kinase. (435 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (307 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (811 aa)
BAG5BCL2 associated athanogene 5. (450 aa)
YOD1YOD1 deubiquitinase. (345 aa)
U3I1L7_ANAPPUncharacterized protein. (199 aa)
MC4RMelanocortin 4 receptor. (331 aa)
SMAD7Mothers against decapentaplegic homolog. (369 aa)
SMAD6Mothers against decapentaplegic homolog. (486 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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