22 items (Anas platyrhynchos) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BRD8	Bromodomain containing 8. (1367 aa)
	MED4	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (278 aa)
	ACACB	Acetyl-CoA carboxylase beta. (2152 aa)
	ENSAPLP00000027377	Uncharacterized protein. (242 aa)
	ENSAPLP00000026183	Uncharacterized protein. (162 aa)
	ACACA	Acetyl-CoA carboxylase alpha. (2444 aa)
	ENSAPLP00000025743	Uncharacterized protein. (462 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1474 aa)
	TACC1	Transforming acidic coiled-coil containing protein 1. (384 aa)
	ENSAPLP00000018112	Uncharacterized protein. (346 aa)
	MED17	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (643 aa)
	GTF2B	General transcription factor IIB. (316 aa)
	MED30	Mediator complex subunit 30. (181 aa)
	NCOA6	Nuclear receptor coactivator 6. (1964 aa)
	TAF7	TATA-box binding protein associated factor 7. (353 aa)
	NR0B2	Nuclear receptor subfamily 0 group B member 2. (267 aa)
	MED13	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2194 aa)
	THRAP3	Thyroid hormone receptor associated protein 3. (966 aa)
	MED16	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (333 aa)
	GTF2H1	General transcription factor IIH subunit 1. (557 aa)
	U3IBF2_ANAPP	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (596 aa)
	NSD1	Nuclear receptor binding SET domain protein 1. (2293 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000018112	NSD1	ENSAPLP00000018112	ENSAPLP00000002635	Uncharacterized protein.	Nuclear receptor binding SET domain protein 1.	0.555
ENSAPLP00000025743	ENSAPLP00000026183	ENSAPLP00000025743	ENSAPLP00000026183	Uncharacterized protein.	Uncharacterized protein.	0.568
ENSAPLP00000025743	ENSAPLP00000027377	ENSAPLP00000025743	ENSAPLP00000027377	Uncharacterized protein.	Uncharacterized protein.	0.933
ENSAPLP00000025743	GTF2B	ENSAPLP00000025743	ENSAPLP00000014972	Uncharacterized protein.	General transcription factor IIB.	0.540
ENSAPLP00000025743	GTF2H1	ENSAPLP00000025743	ENSAPLP00000005213	Uncharacterized protein.	General transcription factor IIH subunit 1.	0.487
ENSAPLP00000025743	MED1	ENSAPLP00000025743	ENSAPLP00000022023	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.904
ENSAPLP00000025743	MED13	ENSAPLP00000025743	ENSAPLP00000009868	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.858
ENSAPLP00000025743	MED16	ENSAPLP00000025743	ENSAPLP00000006459	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.929
ENSAPLP00000025743	MED17	ENSAPLP00000025743	ENSAPLP00000014984	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.912
ENSAPLP00000025743	MED30	ENSAPLP00000025743	ENSAPLP00000014733	Uncharacterized protein.	Mediator complex subunit 30.	0.905
ENSAPLP00000025743	MED4	ENSAPLP00000025743	ENSAPLP00000032401	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.907
ENSAPLP00000025743	U3IBF2_ANAPP	ENSAPLP00000025743	ENSAPLP00000004574	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.866
ENSAPLP00000026183	ENSAPLP00000025743	ENSAPLP00000026183	ENSAPLP00000025743	Uncharacterized protein.	Uncharacterized protein.	0.568
ENSAPLP00000026183	GTF2B	ENSAPLP00000026183	ENSAPLP00000014972	Uncharacterized protein.	General transcription factor IIB.	0.540
ENSAPLP00000026183	GTF2H1	ENSAPLP00000026183	ENSAPLP00000005213	Uncharacterized protein.	General transcription factor IIH subunit 1.	0.487
ENSAPLP00000026183	MED1	ENSAPLP00000026183	ENSAPLP00000022023	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.904
ENSAPLP00000026183	MED13	ENSAPLP00000026183	ENSAPLP00000009868	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.858
ENSAPLP00000026183	MED16	ENSAPLP00000026183	ENSAPLP00000006459	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.929
ENSAPLP00000026183	MED17	ENSAPLP00000026183	ENSAPLP00000014984	Uncharacterized protein.	Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.912
ENSAPLP00000026183	MED30	ENSAPLP00000026183	ENSAPLP00000014733	Uncharacterized protein.	Mediator complex subunit 30.	0.905