(54 nodes) Presynaptic active zone network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	ENSAPLP00000028537	Uncharacterized protein. (1061 aa)
	ENSAPLP00000025176	Uncharacterized protein. (153 aa)
	C1QBP	Complement C1q binding protein. (162 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa)
	NRXN1	Neurexin 1. (1503 aa)
	PPFIA2	PTPRF interacting protein alpha 2. (1283 aa)
	TPRG1L	HSac2 domain-containing protein. (77 aa)
	CPLX3	Complexin 3. (145 aa)
	ZZEF1	Zinc finger ZZ-type and EF-hand domain containing 1. (2910 aa)
	STX11	Syntaxin 11. (288 aa)
	STX19	Syntaxin 19; Belongs to the syntaxin family. (291 aa)
	UNC13B	Unc-13 homolog B. (1636 aa)
	RIMS3	Regulating synaptic membrane exocytosis 3. (299 aa)
	ERC2	ELKS/RAB6-interacting/CAST family member 2. (699 aa)
	P2RX1	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (390 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (912 aa)
	NUFIP1	Nuclear FMR1 interacting protein 1. (525 aa)
	GAD1	Glutamate decarboxylase 1. (563 aa)
	PPFIA1	PTPRF interacting protein alpha 1. (1207 aa)
	NTNG1	Netrin G1. (459 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
	STX1A	Syntaxin 1A; Belongs to the syntaxin family. (285 aa)
	ERC1	ELKS/RAB6-interacting/CAST family member 1. (927 aa)
	SHANK2	SH3 and multiple ankyrin repeat domains 2. (1462 aa)
	PNISR	PNN interacting serine and arginine rich protein. (449 aa)
	SLC32A1	Solute carrier family 32 member 1. (521 aa)
	UNC13C	Unc-13 homolog C. (1091 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (929 aa)
	APBA1	Amyloid beta precursor protein binding family A member 1. (823 aa)
	APP	Amyloid beta precursor protein. (717 aa)
	PPFIBP1	Uncharacterized protein. (907 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (1033 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1379 aa)
	U3IZ19_ANAPP	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (440 aa)
	GPER1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (357 aa)
	U3J0K7_ANAPP	Aa_trans domain-containing protein. (482 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	U3J275_ANAPP	Zf-piccolo domain-containing protein. (516 aa)
	PCLO	Uncharacterized protein. (1161 aa)
	STX3	t-SNARE coiled-coil homology domain-containing protein. (118 aa)
	CTBP2	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (445 aa)
	ENSAPLP00000029499	Uncharacterized protein. (163 aa)
	SYT11	Synaptotagmin 11. (430 aa)
	NPTN	Neuroplastin. (360 aa)
	NTNG2	Netrin G2. (335 aa)
	PPFIBP2	PPFIA binding protein 2. (1012 aa)
	STX2	Syntaxin 2; Belongs to the syntaxin family. (288 aa)
	PPFIA4	PTPRF interacting protein alpha 4. (1201 aa)
	BSN	Zf-piccolo domain-containing protein. (453 aa)
	ENSAPLP00000029757	Uncharacterized protein. (353 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1306 aa)
	STX1B	Syntaxin 1B. (197 aa)
	CDH15	Cadherin 15. (565 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	APP	ENSAPLP00000008593	ENSAPLP00000008622	Amyloid beta precursor protein binding family A member 1.	Amyloid beta precursor protein.	0.900
APBA1	ENSAPLP00000029757	ENSAPLP00000008593	ENSAPLP00000029757	Amyloid beta precursor protein binding family A member 1.	Uncharacterized protein.	0.672
APBA1	RIMS1	ENSAPLP00000008593	ENSAPLP00000010257	Amyloid beta precursor protein binding family A member 1.	Regulating synaptic membrane exocytosis 1.	0.454
APBA1	RIMS3	ENSAPLP00000008593	ENSAPLP00000002570	Amyloid beta precursor protein binding family A member 1.	Regulating synaptic membrane exocytosis 3.	0.454
APBA1	STX11	ENSAPLP00000008593	ENSAPLP00000000129	Amyloid beta precursor protein binding family A member 1.	Syntaxin 11.	0.482
APBA1	STX19	ENSAPLP00000008593	ENSAPLP00000001037	Amyloid beta precursor protein binding family A member 1.	Syntaxin 19; Belongs to the syntaxin family.	0.459
APBA1	STX1A	ENSAPLP00000008593	ENSAPLP00000005649	Amyloid beta precursor protein binding family A member 1.	Syntaxin 1A; Belongs to the syntaxin family.	0.637
APBA1	STX1B	ENSAPLP00000008593	ENSAPLP00000030734	Amyloid beta precursor protein binding family A member 1.	Syntaxin 1B.	0.637
APBA1	STX2	ENSAPLP00000008593	ENSAPLP00000017428	Amyloid beta precursor protein binding family A member 1.	Syntaxin 2; Belongs to the syntaxin family.	0.637
APBA1	STX3	ENSAPLP00000008593	ENSAPLP00000013866	Amyloid beta precursor protein binding family A member 1.	t-SNARE coiled-coil homology domain-containing protein.	0.637
APBA1	UNC13B	ENSAPLP00000008593	ENSAPLP00000002538	Amyloid beta precursor protein binding family A member 1.	Unc-13 homolog B.	0.421
APBA1	UNC13C	ENSAPLP00000008593	ENSAPLP00000007116	Amyloid beta precursor protein binding family A member 1.	Unc-13 homolog C.	0.421
APP	APBA1	ENSAPLP00000008622	ENSAPLP00000008593	Amyloid beta precursor protein.	Amyloid beta precursor protein binding family A member 1.	0.900
APP	CTNNB1	ENSAPLP00000008622	ENSAPLP00000013346	Amyloid beta precursor protein.	Catenin beta 1.	0.414
APP	SYT11	ENSAPLP00000008622	ENSAPLP00000014514	Amyloid beta precursor protein.	Synaptotagmin 11.	0.458
BSN	CTBP1	ENSAPLP00000018652	ENSAPLP00000021618	Zf-piccolo domain-containing protein.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.520
BSN	CTBP2	ENSAPLP00000018652	ENSAPLP00000014327	Zf-piccolo domain-containing protein.	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.520
BSN	EGFLAM	ENSAPLP00000018652	ENSAPLP00000010007	Zf-piccolo domain-containing protein.	EGF like, fibronectin type III and laminin G domains.	0.435
BSN	ENSAPLP00000028537	ENSAPLP00000018652	ENSAPLP00000028537	Zf-piccolo domain-containing protein.	Uncharacterized protein.	0.924
BSN	PCLO	ENSAPLP00000018652	ENSAPLP00000013745	Zf-piccolo domain-containing protein.	Uncharacterized protein.	0.936