STRINGSTRING
LGR4 LGR4 NOG NOG CAV1 CAV1 BAK1 BAK1 HGF HGF PIK3CB PIK3CB TRIM24 TRIM24 FLCN FLCN FGF7 FGF7 PPARD PPARD U3IBF2_ANAPP U3IBF2_ANAPP TNFSF11 TNFSF11 NOX5 NOX5 IFT57 IFT57 IFT52 IFT52 KDR KDR LOXL2 LOXL2 AR AR CCN3 CCN3 ITGB1BP1 ITGB1BP1 MTSS1 MTSS1 SDR16C5 SDR16C5 PRKX PRKX SMO SMO RB1 RB1 PHOX2B PHOX2B A4GNT A4GNT BMPR2 BMPR2 BTRC BTRC DRD2 DRD2 FGL1 FGL1 TGFBR1 TGFBR1 KDF1 KDF1 EHF EHF PROK2 PROK2 CYP7B1 CYP7B1 TEK TEK EREG EREG SOX9 SOX9 U3J0W0_ANAPP U3J0W0_ANAPP WDR77 WDR77 NCSTN NCSTN LGR5 LGR5 PROK1 PROK1 PSEN1 PSEN1 ST8SIA1 ST8SIA1 SAV1 SAV1 IFT74 IFT74 PDX1 PDX1 IL6 IL6 CEBPB CEBPB MED1 MED1 ESRP2 ESRP2 ENSAPLP00000023501 ENSAPLP00000023501 AREG AREG NRARP NRARP IFT172 IFT172 NKX3-1 NKX3-1 IFT80 IFT80 WNT16 WNT16 BCL2L1 BCL2L1 ID2 ID2 SERPINF1 SERPINF1 EFNB2 EFNB2 ENSAPLP00000026712 ENSAPLP00000026712 SCARB1 SCARB1 CAV2 CAV2 XBP1 XBP1 NKX2-8 NKX2-8 NKX2-5 NKX2-5 BMPER BMPER TP63 TP63 ENSAPLP00000032361 ENSAPLP00000032361 IGFBP4 IGFBP4 HNF1B HNF1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (885 aa)
NOGNoggin; Belongs to the noggin family. (223 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
BAK1BCL2 antagonist/killer 1. (306 aa)
HGFUncharacterized protein. (183 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
TRIM24Tripartite motif containing 24. (986 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
PPARDPeroxisome proliferator activated receptor delta. (381 aa)
U3IBF2_ANAPPMediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (596 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
NOX5NADPH oxidase 5. (727 aa)
IFT57Intraflagellar transport 57. (151 aa)
IFT52Intraflagellar transport 52. (439 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
LOXL2Lysyl oxidase like 2. (789 aa)
ARAndrogen receptor. (385 aa)
CCN3Cellular communication network factor 3. (444 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
MTSS1MTSS I-BAR domain containing 1. (795 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa)
PRKXUncharacterized protein. (345 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (620 aa)
RB1RB transcriptional corepressor 1. (855 aa)
PHOX2BPaired like homeobox 2B. (235 aa)
A4GNTGb3_synth domain-containing protein. (338 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1000 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (608 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
FGL1Fibrinogen like 1. (350 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
KDF1Keratinocyte differentiation factor 1. (418 aa)
EHFETS homologous factor. (298 aa)
PROK2Prokineticin 2. (132 aa)
CYP7B1Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (504 aa)
TEKTEK receptor tyrosine kinase. (1128 aa)
EREGEpiregulin. (148 aa)
SOX9SRY-box transcription factor 9. (489 aa)
U3J0W0_ANAPPUncharacterized protein. (328 aa)
WDR77WD repeat domain 77. (371 aa)
NCSTNNicastrin. (719 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (837 aa)
PROK1Prokineticin 1. (125 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa)
SAV1Salvador family WW domain containing protein 1. (386 aa)
IFT74Intraflagellar transport 74. (598 aa)
PDX1Homeobox domain-containing protein. (264 aa)
IL6Uncharacterized protein. (350 aa)
CEBPBCCAAT/enhancer-binding protein. (306 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1474 aa)
ESRP2Epithelial splicing regulatory protein 2. (728 aa)
ENSAPLP00000023501SRCR domain-containing protein. (269 aa)
AREGAmphiregulin. (212 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
IFT172Intraflagellar transport 172. (2096 aa)
NKX3-1NK3 homeobox 1. (280 aa)
IFT80Intraflagellar transport 80. (784 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
BCL2L1BCL2 like 1. (238 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (520 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
ENSAPLP00000026712Uncharacterized protein. (156 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (504 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
XBP1X-box binding protein 1. (313 aa)
NKX2-8NK2 homeobox 8. (236 aa)
NKX2-5NK2 homeobox 5. (295 aa)
BMPERBMP binding endothelial regulator. (784 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ENSAPLP00000032361IGFBP N-terminal domain-containing protein. (122 aa)
IGFBP4Thyroglobulin type-1 domain-containing protein. (338 aa)
HNF1BHNF1 homeobox B. (691 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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