STRINGSTRING
TRAF5 TRAF5 GREM1 GREM1 U3HZF0_ANAPP U3HZF0_ANAPP ADCY1 ADCY1 LPAR5 LPAR5 U3I0R1_ANAPP U3I0R1_ANAPP TERF2IP TERF2IP TIRAP TIRAP CAV1 CAV1 TRIM8 TRIM8 MAVS MAVS SRF SRF BCL10 BCL10 IRAK2 IRAK2 CARD11 CARD11 CYTL1 CYTL1 KIT KIT WHAMM WHAMM RNF25 RNF25 U3IBK2_ANAPP U3IBK2_ANAPP IL18RAP IL18RAP TRIM14 TRIM14 TNFSF11 TNFSF11 ADCY8 ADCY8 IL18 IL18 AR AR BUD31 BUD31 U3IGU3_ANAPP U3IGU3_ANAPP RIPK2 RIPK2 PLPP3 PLPP3 CARD9 CARD9 ABRA ABRA PINK1 PINK1 SMO SMO LRP5 LRP5 PRKCI PRKCI APP APP TLR3 TLR3 RGCC RGCC PRKCZ PRKCZ MALT1 MALT1 LRP8 LRP8 RWDD1 RWDD1 EP300 EP300 U3ISY4_ANAPP U3ISY4_ANAPP PSMA6 PSMA6 ARID5B ARID5B KDM1A KDM1A LRP6 LRP6 CX3CL1 CX3CL1 TNFRSF19 TNFRSF19 U3IYG0_ANAPP U3IYG0_ANAPP SLCO3A1 SLCO3A1 CAPN3 CAPN3 U3J047_ANAPP U3J047_ANAPP MBTPS2 MBTPS2 CTNNB1 CTNNB1 DDR2 DDR2 TFDP1 TFDP1 RPS3 RPS3 JUP JUP DDX58 DDX58 IL10 IL10 RIPK1 RIPK1 DHX33 DHX33 FLOT2 FLOT2 CLUL1 CLUL1 U3J8L2_ANAPP U3J8L2_ANAPP RIPK4 RIPK4 CD40 CD40 EDN1 EDN1 ENSAPLP00000016651 ENSAPLP00000016651 ENSAPLP00000016691 ENSAPLP00000016691 FLOT1 FLOT1 ENSAPLP00000017486 ENSAPLP00000017486 NTS NTS ARHGEF5 ARHGEF5 SAV1 SAV1 ENSAPLP00000018903 ENSAPLP00000018903 ENSAPLP00000019469 ENSAPLP00000019469 PPARGC1B PPARGC1B COPS5 COPS5 STK36 STK36 ENSAPLP00000020265 ENSAPLP00000020265 IL6 IL6 ENSAPLP00000021229 ENSAPLP00000021229 PPRC1 PPRC1 ENSAPLP00000022326 ENSAPLP00000022326 ENSAPLP00000022617 ENSAPLP00000022617 JMY JMY EIF2AK2 EIF2AK2 NOD1 NOD1 TRAPPC9 TRAPPC9 NKX3-1 NKX3-1 TRAF2 TRAF2 ENSAPLP00000024408 ENSAPLP00000024408 TRADD TRADD MYOCD MYOCD CHUK CHUK ROR1 ROR1 NDP NDP MTPN MTPN SMARCB1 SMARCB1 ENSAPLP00000026426 ENSAPLP00000026426 ENSAPLP00000026777 ENSAPLP00000026777 TRIM37 TRIM37 NEUROD1 NEUROD1 CRTC1 CRTC1 IHH IHH TRIM32 TRIM32 TRAF1 TRAF1 TNFRSF11A TNFRSF11A TRAF6 TRAF6 CAT CAT ENSAPLP00000028846 ENSAPLP00000028846 CRTC2 CRTC2 CTH CTH ENSAPLP00000029593 ENSAPLP00000029593 IKBKB IKBKB ENSAPLP00000029980 ENSAPLP00000029980 ENSAPLP00000030281 ENSAPLP00000030281 TAF12 TAF12 NFAM1 NFAM1 PPARGC1A PPARGC1A PRDX3 PRDX3 ZC4H2 ZC4H2 FZD4 FZD4 ENSAPLP00000032571 ENSAPLP00000032571 ENSAPLP00000032667 ENSAPLP00000032667 EDA EDA RNF220 RNF220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
GREM1Gremlin. (184 aa)
U3HZF0_ANAPPCostars domain-containing protein. (75 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (370 aa)
U3I0R1_ANAPPUncharacterized protein. (166 aa)
TERF2IPTERF2 interacting protein. (369 aa)
TIRAPTIR domain containing adaptor protein. (219 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TRIM8Tripartite motif containing 8. (360 aa)
MAVSCARD_2 domain-containing protein. (619 aa)
SRFSerum response factor. (516 aa)
BCL10CARD domain-containing protein. (316 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (731 aa)
CARD11Caspase recruitment domain family member 11. (1187 aa)
CYTL1Cytokine like 1. (192 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (964 aa)
WHAMMWASP homolog associated with actin, golgi membranes and microtubules. (771 aa)
RNF25Ring finger protein 25. (400 aa)
U3IBK2_ANAPPUncharacterized protein. (566 aa)
IL18RAPInterleukin 18 receptor accessory protein. (820 aa)
TRIM14Tripartite motif containing 14. (424 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (322 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
IL18Interleukin-18. (197 aa)
ARAndrogen receptor. (385 aa)
BUD31BUD31 homolog. (144 aa)
U3IGU3_ANAPPB30.2/SPRY domain-containing protein. (185 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (552 aa)
PLPP3acidPPc domain-containing protein. (313 aa)
CARD9Caspase recruitment domain family member 9. (518 aa)
ABRAActin binding Rho activating protein. (408 aa)
PINK1PTEN induced kinase 1. (603 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (620 aa)
LRP5Uncharacterized protein. (471 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
APPAmyloid beta precursor protein. (717 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (914 aa)
RGCCRegulator of cell cycle. (133 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
MALT1MALT1 paracaspase. (816 aa)
LRP8LDL receptor related protein 8. (917 aa)
RWDD1RWD domain containing 1. (285 aa)
EP300E1A binding protein p300. (2355 aa)
U3ISY4_ANAPPANK_REP_REGION domain-containing protein. (191 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
ARID5BAT-rich interaction domain 5B. (1139 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (829 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1603 aa)
CX3CL1SCY domain-containing protein. (481 aa)
TNFRSF19TNF receptor superfamily member 19. (408 aa)
U3IYG0_ANAPPCTCK domain-containing protein. (126 aa)
SLCO3A1Solute carrier organic anion transporter family member. (716 aa)
CAPN3Calpain 3; Belongs to the peptidase C2 family. (811 aa)
U3J047_ANAPPUncharacterized protein. (63 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (494 aa)
CTNNB1Catenin beta 1. (781 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (855 aa)
TFDP1Transcription factor. (412 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
JUPJunction plakoglobin. (732 aa)
DDX58DExD/H-box helicase 58. (880 aa)
IL10Interleukin 10. (177 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
DHX33Helicase C-terminal domain-containing protein. (405 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (331 aa)
CLUL1Clusterin; Belongs to the clusterin family. (461 aa)
U3J8L2_ANAPPUncharacterized protein. (803 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (787 aa)
CD40TNFR-Cys domain-containing protein. (214 aa)
EDN1Endothelin 1. (203 aa)
ENSAPLP00000016651RING-type domain-containing protein. (53 aa)
ENSAPLP00000016691Uncharacterized protein. (235 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (287 aa)
ENSAPLP00000017486Helicase ATP-binding domain-containing protein. (200 aa)
NTSNeurotensin. (327 aa)
ARHGEF5Uncharacterized protein. (1542 aa)
SAV1Salvador family WW domain containing protein 1. (386 aa)
ENSAPLP00000018903Uncharacterized protein. (582 aa)
ENSAPLP00000019469Uncharacterized protein. (318 aa)
PPARGC1BPPARG coactivator 1 beta. (1020 aa)
COPS5COP9 signalosome subunit 5. (414 aa)
STK36Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (151 aa)
ENSAPLP00000020265Uncharacterized protein. (462 aa)
IL6Uncharacterized protein. (350 aa)
ENSAPLP00000021229ANK_REP_REGION domain-containing protein. (186 aa)
PPRC1Uncharacterized protein. (73 aa)
ENSAPLP00000022326Uncharacterized protein. (263 aa)
ENSAPLP00000022617Uncharacterized protein. (721 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (895 aa)
EIF2AK2Eukaryotic translation initiation factor 2 alpha kinase 2; Belongs to the protein kinase superfamily. (483 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (951 aa)
TRAPPC9Trafficking protein particle complex 9. (1003 aa)
NKX3-1NK3 homeobox 1. (280 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
ENSAPLP00000024408Uncharacterized protein. (442 aa)
TRADDTNFRSF1A associated via death domain. (429 aa)
MYOCDMyocardin. (1032 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (757 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa)
NDPNorrin cystine knot growth factor NDP. (114 aa)
MTPNMyotrophin. (380 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (381 aa)
ENSAPLP00000026426Protein kinase domain-containing protein. (144 aa)
ENSAPLP00000026777Tyrosine-protein kinase receptor. (481 aa)
TRIM37Tripartite motif containing 37. (1025 aa)
NEUROD1Neurogenic differentiation factor. (359 aa)
CRTC1CREB regulated transcription coactivator 1. (724 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (757 aa)
TRIM32Tripartite motif containing 32. (715 aa)
TRAF1TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
TNFRSF11ATNF receptor superfamily member 11a. (652 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
ENSAPLP00000028846Uncharacterized protein. (324 aa)
CRTC2CREB regulated transcription coactivator 2. (348 aa)
CTHCystathionine gamma-lyase. (607 aa)
ENSAPLP00000029593EF-hand domain-containing protein. (396 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
ENSAPLP00000029980Uncharacterized protein. (148 aa)
ENSAPLP00000030281Uncharacterized protein. (885 aa)
TAF12TATA-box binding protein associated factor 12. (247 aa)
NFAM1Ig-like domain-containing protein. (248 aa)
PPARGC1APPARG coactivator 1 alpha. (834 aa)
PRDX3Peroxiredoxin 3. (264 aa)
ZC4H2Zinc finger C4H2-type containing. (224 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
ENSAPLP00000032571TNFR-Cys domain-containing protein. (677 aa)
ENSAPLP00000032667Uncharacterized protein. (268 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (243 aa)
RNF220Ring finger protein 220. (678 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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