(7 nodes) Growth hormone receptor signaling pathway via JAK-STAT network (Anas platyrhynchos)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	ENSAPLP00000024738	Uncharacterized protein. (257 aa)
	STAT3	Signal transducer and activator of transcription. (942 aa)
	ENSAPLP00000032274	Protein kinase domain-containing protein. (192 aa)
	ENSAPLP00000031961	Protein kinase domain-containing protein. (220 aa)
	JAK1	Tyrosine-protein kinase. (1152 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	JAK3	Uncharacterized protein. (501 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000024738	ENSAPLP00000031961	ENSAPLP00000024738	ENSAPLP00000031961	Uncharacterized protein.	Protein kinase domain-containing protein.	0.800
ENSAPLP00000024738	ENSAPLP00000032274	ENSAPLP00000024738	ENSAPLP00000032274	Uncharacterized protein.	Protein kinase domain-containing protein.	0.981
ENSAPLP00000024738	JAK1	ENSAPLP00000024738	ENSAPLP00000011906	Uncharacterized protein.	Tyrosine-protein kinase.	0.987
ENSAPLP00000024738	JAK2	ENSAPLP00000024738	ENSAPLP00000027035	Uncharacterized protein.	Tyrosine-protein kinase.	0.979
ENSAPLP00000024738	JAK3	ENSAPLP00000024738	ENSAPLP00000018342	Uncharacterized protein.	Uncharacterized protein.	0.800
ENSAPLP00000024738	STAT3	ENSAPLP00000024738	ENSAPLP00000007496	Uncharacterized protein.	Signal transducer and activator of transcription.	0.939
ENSAPLP00000031961	ENSAPLP00000024738	ENSAPLP00000031961	ENSAPLP00000024738	Protein kinase domain-containing protein.	Uncharacterized protein.	0.800
ENSAPLP00000031961	ENSAPLP00000032274	ENSAPLP00000031961	ENSAPLP00000032274	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.665
ENSAPLP00000031961	JAK1	ENSAPLP00000031961	ENSAPLP00000011906	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.544
ENSAPLP00000031961	JAK3	ENSAPLP00000031961	ENSAPLP00000018342	Protein kinase domain-containing protein.	Uncharacterized protein.	0.899
ENSAPLP00000031961	STAT3	ENSAPLP00000031961	ENSAPLP00000007496	Protein kinase domain-containing protein.	Signal transducer and activator of transcription.	0.869
ENSAPLP00000032274	ENSAPLP00000024738	ENSAPLP00000032274	ENSAPLP00000024738	Protein kinase domain-containing protein.	Uncharacterized protein.	0.981
ENSAPLP00000032274	ENSAPLP00000031961	ENSAPLP00000032274	ENSAPLP00000031961	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.665
ENSAPLP00000032274	JAK1	ENSAPLP00000032274	ENSAPLP00000011906	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.963
ENSAPLP00000032274	JAK2	ENSAPLP00000032274	ENSAPLP00000027035	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.963
ENSAPLP00000032274	JAK3	ENSAPLP00000032274	ENSAPLP00000018342	Protein kinase domain-containing protein.	Uncharacterized protein.	0.963
ENSAPLP00000032274	STAT3	ENSAPLP00000032274	ENSAPLP00000007496	Protein kinase domain-containing protein.	Signal transducer and activator of transcription.	0.982
JAK1	ENSAPLP00000024738	ENSAPLP00000011906	ENSAPLP00000024738	Tyrosine-protein kinase.	Uncharacterized protein.	0.987
JAK1	ENSAPLP00000031961	ENSAPLP00000011906	ENSAPLP00000031961	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.544
JAK1	ENSAPLP00000032274	ENSAPLP00000011906	ENSAPLP00000032274	Tyrosine-protein kinase.	Protein kinase domain-containing protein.	0.963