(14 nodes) Response to growth hormone network (Anas platyrhynchos)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPLP00000032274	Protein kinase domain-containing protein. (192 aa)
	ENSAPLP00000032361	IGFBP N-terminal domain-containing protein. (122 aa)
	ENSAPLP00000031961	Protein kinase domain-containing protein. (220 aa)
	JAK2	Tyrosine-protein kinase. (1130 aa)
	ENSAPLP00000024738	Uncharacterized protein. (257 aa)
	GHR	Growth hormone receptor. (644 aa)
	JAK3	Uncharacterized protein. (501 aa)
	PHEX	Phosphate regulating endopeptidase homolog X-linked. (747 aa)
	CHAT	Choline O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (636 aa)
	JAK1	Tyrosine-protein kinase. (1152 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	STAT3	Signal transducer and activator of transcription. (942 aa)
	GH1	Uncharacterized protein. (222 aa)
	SOCS2	Suppressor of cytokine signaling 2. (143 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000024738	ENSAPLP00000031961	ENSAPLP00000024738	ENSAPLP00000031961	Uncharacterized protein.	Protein kinase domain-containing protein.	0.800
ENSAPLP00000024738	ENSAPLP00000032274	ENSAPLP00000024738	ENSAPLP00000032274	Uncharacterized protein.	Protein kinase domain-containing protein.	0.981
ENSAPLP00000024738	GH1	ENSAPLP00000024738	ENSAPLP00000004085	Uncharacterized protein.	Uncharacterized protein.	0.474
ENSAPLP00000024738	GHR	ENSAPLP00000024738	ENSAPLP00000021153	Uncharacterized protein.	Growth hormone receptor.	0.780
ENSAPLP00000024738	JAK1	ENSAPLP00000024738	ENSAPLP00000011906	Uncharacterized protein.	Tyrosine-protein kinase.	0.987
ENSAPLP00000024738	JAK2	ENSAPLP00000024738	ENSAPLP00000027035	Uncharacterized protein.	Tyrosine-protein kinase.	0.979
ENSAPLP00000024738	JAK3	ENSAPLP00000024738	ENSAPLP00000018342	Uncharacterized protein.	Uncharacterized protein.	0.800
ENSAPLP00000024738	SOCS2	ENSAPLP00000024738	ENSAPLP00000000986	Uncharacterized protein.	Suppressor of cytokine signaling 2.	0.678
ENSAPLP00000024738	STAT3	ENSAPLP00000024738	ENSAPLP00000007496	Uncharacterized protein.	Signal transducer and activator of transcription.	0.939
ENSAPLP00000031961	ENSAPLP00000024738	ENSAPLP00000031961	ENSAPLP00000024738	Protein kinase domain-containing protein.	Uncharacterized protein.	0.800
ENSAPLP00000031961	ENSAPLP00000032274	ENSAPLP00000031961	ENSAPLP00000032274	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.665
ENSAPLP00000031961	GH1	ENSAPLP00000031961	ENSAPLP00000004085	Protein kinase domain-containing protein.	Uncharacterized protein.	0.553
ENSAPLP00000031961	GHR	ENSAPLP00000031961	ENSAPLP00000021153	Protein kinase domain-containing protein.	Growth hormone receptor.	0.957
ENSAPLP00000031961	JAK1	ENSAPLP00000031961	ENSAPLP00000011906	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.544
ENSAPLP00000031961	JAK3	ENSAPLP00000031961	ENSAPLP00000018342	Protein kinase domain-containing protein.	Uncharacterized protein.	0.899
ENSAPLP00000031961	SOCS2	ENSAPLP00000031961	ENSAPLP00000000986	Protein kinase domain-containing protein.	Suppressor of cytokine signaling 2.	0.434
ENSAPLP00000031961	STAT3	ENSAPLP00000031961	ENSAPLP00000007496	Protein kinase domain-containing protein.	Signal transducer and activator of transcription.	0.869
ENSAPLP00000032274	ENSAPLP00000024738	ENSAPLP00000032274	ENSAPLP00000024738	Protein kinase domain-containing protein.	Uncharacterized protein.	0.981
ENSAPLP00000032274	ENSAPLP00000031961	ENSAPLP00000032274	ENSAPLP00000031961	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.665
ENSAPLP00000032274	GH1	ENSAPLP00000032274	ENSAPLP00000004085	Protein kinase domain-containing protein.	Uncharacterized protein.	0.412