STRINGSTRING
LATS2 LATS2 GREM1 GREM1 RNF146 RNF146 SMAD6 SMAD6 NOG NOG TMEM170B TMEM170B U3I0R1_ANAPP U3I0R1_ANAPP PRDM15 PRDM15 FZD7 FZD7 RSPO3 RSPO3 USP8 USP8 CAV1 CAV1 TNKS TNKS NPHP4 NPHP4 TLE2 TLE2 TMEM131L TMEM131L TNN TNN CSNK1G3 CSNK1G3 CTHRC1 CTHRC1 LGR4 LGR4 WNT2 WNT2 PTK7 PTK7 U3I7N4_ANAPP U3I7N4_ANAPP NLE1 NLE1 U3I8F2_ANAPP U3I8F2_ANAPP UBR5 UBR5 CDH2 CDH2 TLE4 TLE4 UBAC2 UBAC2 CSNK1G1 CSNK1G1 CSNK1D CSNK1D USP34 USP34 PPM1A PPM1A TBL1X TBL1X GID8 GID8 SFRP1 SFRP1 RUVBL1 RUVBL1 DKK2 DKK2 AXIN1 AXIN1 OTULIN OTULIN MKS1 MKS1 LYPD6 LYPD6 CAPRIN2 CAPRIN2 U3IGM9_ANAPP U3IGM9_ANAPP STK11 STK11 GPC5 GPC5 CCNYL1 CCNYL1 TMEM88B TMEM88B SOSTDC1 SOSTDC1 BTRC BTRC SHISA3 SHISA3 U3ILH3_ANAPP U3ILH3_ANAPP RPS12 RPS12 U3IM41_ANAPP U3IM41_ANAPP U3IMS8_ANAPP U3IMS8_ANAPP DAB2 DAB2 LATS1 LATS1 BAMBI BAMBI ILK ILK DRAXIN DRAXIN WNT11 WNT11 CSNK1A1 CSNK1A1 CSNK1G2 CSNK1G2 AXIN2 AXIN2 TNKS2 TNKS2 DAAM2 DAAM2 LRRK2 LRRK2 TMEM64 TMEM64 WNK2 WNK2 TTC21B TTC21B PTPRO PTPRO SOX9 SOX9 TBL1XR1 TBL1XR1 CTNNB1 CTNNB1 WNT8A WNT8A CCNY CCNY CBY1 CBY1 PIN1 PIN1 WNT2B WNT2B U3J4W3_ANAPP U3J4W3_ANAPP WLS WLS FAM53B FAM53B JADE1 JADE1 BICC1 BICC1 USP47 USP47 MDK MDK LGR5 LGR5 DKK3 DKK3 U3J9B6_ANAPP U3J9B6_ANAPP SFRP5 SFRP5 CDK14 CDK14 MCC MCC GPC3 GPC3 PSEN1 PSEN1 ENSAPLP00000018111 ENSAPLP00000018111 ENSAPLP00000018432 ENSAPLP00000018432 ENSAPLP00000018529 ENSAPLP00000018529 RSPO1 RSPO1 DACT1 DACT1 NKD1 NKD1 HDAC1 HDAC1 SOX13 SOX13 LZTS2 LZTS2 ENSAPLP00000020785 ENSAPLP00000020785 ENSAPLP00000020910 ENSAPLP00000020910 OTULINL OTULINL DKK1 DKK1 ENSAPLP00000021206 ENSAPLP00000021206 CTNNBIP1 CTNNBIP1 SCYL2 SCYL2 ENSAPLP00000022384 ENSAPLP00000022384 PPM1B PPM1B SFRP4 SFRP4 ENSAPLP00000022809 ENSAPLP00000022809 KREMEN1 KREMEN1 ENSAPLP00000023332 ENSAPLP00000023332 NRARP NRARP DLX5 DLX5 TMEM9 TMEM9 GSKIP GSKIP XIAP XIAP ENSAPLP00000024797 ENSAPLP00000024797 APC2 APC2 ENSAPLP00000025816 ENSAPLP00000025816 PRKN PRKN GSK3B GSK3B LRRK1 LRRK1 NOTUM NOTUM ENSAPLP00000026686 ENSAPLP00000026686 TLE3 TLE3 TPBG TPBG AMER2 AMER2 RECK RECK CYLD CYLD ENSAPLP00000027687 ENSAPLP00000027687 TLE1 TLE1 ENSAPLP00000028340 ENSAPLP00000028340 SOST SOST ENSAPLP00000028552 ENSAPLP00000028552 LYPD6B LYPD6B TLE5 TLE5 WWTR1 WWTR1 SFRP2 SFRP2 RSPO2 RSPO2 IFT20 IFT20 ENSAPLP00000029860 ENSAPLP00000029860 CAPRIN2-2 CAPRIN2-2 ATP6AP2 ATP6AP2 ENSAPLP00000030691 ENSAPLP00000030691 ENSAPLP00000030759 ENSAPLP00000030759 APC APC DAAM1 DAAM1 FZD4 FZD4 G3BP1 G3BP1 NKX2-5 NKX2-5 ZNF703 ZNF703 AMER1 AMER1 AMER3 AMER3 WNT3A WNT3A EDA EDA CDH15 CDH15 SOX7 SOX7 RNF220 RNF220
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LATS2Non-specific serine/threonine protein kinase. (1126 aa)
GREM1Gremlin. (184 aa)
RNF146Ring finger protein 146. (352 aa)
SMAD6Mothers against decapentaplegic homolog. (486 aa)
NOGNoggin; Belongs to the noggin family. (223 aa)
TMEM170BUncharacterized protein. (132 aa)
U3I0R1_ANAPPUncharacterized protein. (166 aa)
PRDM15PR/SET domain 15. (1104 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (573 aa)
RSPO3R-spondin 3. (319 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1149 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TNKSPoly [ADP-ribose] polymerase. (1143 aa)
NPHP4Nephrocystin 4. (1287 aa)
TLE2WD_REPEATS_REGION domain-containing protein. (264 aa)
TMEM131LTransmembrane 131 like. (1532 aa)
TNNTenascin N. (1123 aa)
CSNK1G3Casein kinase 1 gamma 3; Belongs to the protein kinase superfamily. (456 aa)
CTHRC1Collagen triple helix repeat containing 1. (271 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (885 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (319 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1125 aa)
U3I7N4_ANAPPUncharacterized protein. (537 aa)
NLE1Notchless homolog 1. (461 aa)
U3I8F2_ANAPPFZ domain-containing protein. (127 aa)
UBR5UBR-type domain-containing protein. (1953 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (912 aa)
TLE4Uncharacterized protein. (700 aa)
UBAC2UBA domain containing 2. (460 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (456 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (409 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3522 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (382 aa)
TBL1XUncharacterized protein. (523 aa)
GID8GID complex subunit 8 homolog. (228 aa)
SFRP1Secreted frizzled related protein 1. (311 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
DKK2Dickkopf_N domain-containing protein. (348 aa)
AXIN1Axin 1. (841 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (402 aa)
MKS1Uncharacterized protein. (332 aa)
LYPD6LY6/PLAUR domain containing 6. (169 aa)
CAPRIN2Caprin family member 2. (902 aa)
U3IGM9_ANAPPUncharacterized protein. (314 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (440 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (483 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (289 aa)
TMEM88BUncharacterized protein. (159 aa)
SOSTDC1Sclerostin domain containing 1. (209 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (608 aa)
SHISA3Shisa family member 3. (249 aa)
U3ILH3_ANAPPProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
RPS1240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
U3IM41_ANAPPUncharacterized protein. (93 aa)
U3IMS8_ANAPPUncharacterized protein; Belongs to the peptidase C19 family. (807 aa)
DAB2DAB adaptor protein 2. (715 aa)
LATS1Large tumor suppressor kinase 1. (1133 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (259 aa)
ILKIntegrin linked kinase. (500 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family. (349 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (336 aa)
CSNK1G2Uncharacterized protein. (222 aa)
AXIN2DIX domain-containing protein. (274 aa)
TNKS2Poly [ADP-ribose] polymerase. (1109 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1097 aa)
LRRK2Leucine rich repeat kinase 2. (2534 aa)
TMEM64Transmembrane protein 64. (354 aa)
WNK2WNK lysine deficient protein kinase 2. (2275 aa)
TTC21BTetratricopeptide repeat domain 21B. (1338 aa)
PTPROUncharacterized protein. (304 aa)
SOX9SRY-box transcription factor 9. (489 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (513 aa)
CTNNB1Catenin beta 1. (781 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
CCNYCyclin Y; Belongs to the cyclin family. (341 aa)
CBY1Chibby family member 1, beta catenin antagonist. (126 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (149 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
U3J4W3_ANAPPUncharacterized protein. (164 aa)
WLSWnt ligand secretion mediator. (508 aa)
FAM53BFamily with sequence similarity 53 member B. (393 aa)
JADE1Jade family PHD finger 1. (842 aa)
BICC1BicC family RNA binding protein 1. (938 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
MDKMidkine. (142 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (837 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (359 aa)
U3J9B6_ANAPPANK_REP_REGION domain-containing protein. (317 aa)
SFRP5Secreted frizzled related protein 5. (317 aa)
CDK14Cyclin dependent kinase 14; Belongs to the protein kinase superfamily. (484 aa)
MCCMCC regulator of WNT signaling pathway. (1004 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (646 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
ENSAPLP00000018111Uncharacterized protein. (141 aa)
ENSAPLP00000018432Uncharacterized protein. (108 aa)
ENSAPLP00000018529Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (600 aa)
RSPO1R-spondin 1. (260 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (480 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (506 aa)
SOX13SRY-box transcription factor 13. (700 aa)
LZTS2Leucine zipper tumor suppressor 2. (649 aa)
ENSAPLP00000020785RGS domain-containing protein. (143 aa)
ENSAPLP00000020910Uncharacterized protein. (85 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (429 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (271 aa)
ENSAPLP00000021206DUF4203 domain-containing protein. (110 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
SCYL2SCY1 like pseudokinase 2. (1099 aa)
ENSAPLP00000022384Uncharacterized protein. (387 aa)
PPM1BPPM-type phosphatase domain-containing protein. (479 aa)
SFRP4Secreted frizzled related protein 4. (563 aa)
ENSAPLP00000022809LRRCT domain-containing protein. (238 aa)
KREMEN1Kringle containing transmembrane protein 1. (630 aa)
ENSAPLP00000023332Uncharacterized protein. (160 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
DLX5Distal-less homeobox 5. (340 aa)
TMEM9Transmembrane protein 9. (191 aa)
GSKIPGSK3B interacting protein. (337 aa)
XIAPX-linked inhibitor of apoptosis. (493 aa)
ENSAPLP00000024797TLE_N domain-containing protein. (245 aa)
APC2APC regulator of WNT signaling pathway 2. (1940 aa)
ENSAPLP00000025816Uncharacterized protein. (142 aa)
PRKNParkin RBR E3 ubiquitin protein ligase. (520 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (420 aa)
LRRK1Leucine rich repeat kinase 1. (1999 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (360 aa)
ENSAPLP00000026686TLE_N domain-containing protein. (129 aa)
TLE3TLE family member 3, transcriptional corepressor. (690 aa)
TPBGTrophoblast glycoprotein. (227 aa)
AMER2APC membrane recruitment protein 2. (623 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (1031 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (970 aa)
ENSAPLP00000027687Uncharacterized protein. (83 aa)
TLE1TLE family member 1, transcriptional corepressor. (788 aa)
ENSAPLP00000028340TLE_N domain-containing protein. (169 aa)
SOSTSclerostin. (328 aa)
ENSAPLP00000028552Uncharacterized protein. (145 aa)
LYPD6BLY6/PLAUR domain containing 6B. (169 aa)
TLE5TLE family member 5, transcriptional modulator. (165 aa)
WWTR1WW domain containing transcription regulator 1. (269 aa)
SFRP2Secreted frizzled related protein 2. (358 aa)
RSPO2R-spondin 2. (247 aa)
IFT20Uncharacterized protein. (126 aa)
ENSAPLP00000029860Uncharacterized protein. (277 aa)
CAPRIN2-2C1q domain-containing protein. (115 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (404 aa)
ENSAPLP00000030691HECT domain-containing protein. (79 aa)
ENSAPLP00000030759DUF4203 domain-containing protein. (244 aa)
APCAPC regulator of WNT signaling pathway. (2852 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1200 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
G3BP1G3BP stress granule assembly factor 1. (486 aa)
NKX2-5NK2 homeobox 5. (295 aa)
ZNF703Zinc finger protein 703. (488 aa)
AMER1APC membrane recruitment protein 1. (1196 aa)
AMER3Uncharacterized protein. (986 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (243 aa)
CDH15Cadherin 15. (565 aa)
SOX7Uncharacterized protein. (558 aa)
RNF220Ring finger protein 220. (678 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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