20 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ZBTB1	Zinc finger and BTB domain containing 1. (642 aa)
	TNFAIP3	TNF alpha induced protein 3. (870 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (630 aa)
	OTUD7B	OTU deubiquitinase 7B. (918 aa)
	OPTN	Optineurin. (556 aa)
	OTUD7A	OTU deubiquitinase 7A. (935 aa)
	PRPF8	Pre-mRNA processing factor 8. (2241 aa)
	GSAP	Gamma-secretase activating protein. (846 aa)
	SPRTN	SprT-like N-terminal domain. (509 aa)
	ZRANB3	Zinc finger RANBP2-type containing 3. (1100 aa)
	RNF168	E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (609 aa)
	WDR81	WD repeat domain 81. (1921 aa)
	ENSAPLP00000020417	Uncharacterized protein. (288 aa)
	RNF169	Ring finger protein 169. (458 aa)
	FAAP20	Uncharacterized protein. (317 aa)
	SQSTM1	Uncharacterized protein. (77 aa)
	ATRIP	ATR interacting protein. (1045 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (706 aa)
	ZRANB1	Zinc finger RANBP2-type containing 1. (708 aa)
	PARP10	Poly [ADP-ribose] polymerase. (1019 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATRIP	RNF168	ENSAPLP00000028280	ENSAPLP00000015131	ATR interacting protein.	E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...]	0.602
ATRIP	ZRANB3	ENSAPLP00000028280	ENSAPLP00000014680	ATR interacting protein.	Zinc finger RANBP2-type containing 3.	0.593
GSAP	OPTN	ENSAPLP00000011992	ENSAPLP00000004235	Gamma-secretase activating protein.	Optineurin.	0.521
OPTN	GSAP	ENSAPLP00000004235	ENSAPLP00000011992	Optineurin.	Gamma-secretase activating protein.	0.521
OPTN	OTUD7A	ENSAPLP00000004235	ENSAPLP00000006255	Optineurin.	OTU deubiquitinase 7A.	0.405
OPTN	OTUD7B	ENSAPLP00000004235	ENSAPLP00000004164	Optineurin.	OTU deubiquitinase 7B.	0.405
OPTN	SQSTM1	ENSAPLP00000004235	ENSAPLP00000028233	Optineurin.	Uncharacterized protein.	0.633
OPTN	TAB2	ENSAPLP00000004235	ENSAPLP00000028451	Optineurin.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.800
OPTN	TAB3	ENSAPLP00000004235	ENSAPLP00000002363	Optineurin.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.800
OPTN	TNFAIP3	ENSAPLP00000004235	ENSAPLP00000001811	Optineurin.	TNF alpha induced protein 3.	0.405
OPTN	ZRANB1	ENSAPLP00000004235	ENSAPLP00000030554	Optineurin.	Zinc finger RANBP2-type containing 1.	0.405
OTUD7A	OPTN	ENSAPLP00000006255	ENSAPLP00000004235	OTU deubiquitinase 7A.	Optineurin.	0.405
OTUD7A	TNFAIP3	ENSAPLP00000006255	ENSAPLP00000001811	OTU deubiquitinase 7A.	TNF alpha induced protein 3.	0.401
OTUD7A	ZRANB1	ENSAPLP00000006255	ENSAPLP00000030554	OTU deubiquitinase 7A.	Zinc finger RANBP2-type containing 1.	0.470
OTUD7B	OPTN	ENSAPLP00000004164	ENSAPLP00000004235	OTU deubiquitinase 7B.	Optineurin.	0.405
OTUD7B	TNFAIP3	ENSAPLP00000004164	ENSAPLP00000001811	OTU deubiquitinase 7B.	TNF alpha induced protein 3.	0.401
OTUD7B	ZRANB1	ENSAPLP00000004164	ENSAPLP00000030554	OTU deubiquitinase 7B.	Zinc finger RANBP2-type containing 1.	0.440
RNF168	ATRIP	ENSAPLP00000015131	ENSAPLP00000028280	E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...]	ATR interacting protein.	0.602
RNF168	RNF169	ENSAPLP00000015131	ENSAPLP00000024805	E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...]	Ring finger protein 169.	0.534
RNF169	RNF168	ENSAPLP00000024805	ENSAPLP00000015131	Ring finger protein 169.	E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...]	0.534