43 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1149 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
	EGFR	Receptor protein-tyrosine kinase. (1219 aa)
	MATK	Tyrosine-protein kinase. (447 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (330 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	U3IKP8_ANAPP	Uncharacterized protein. (1110 aa)
	SHC1	SHC adaptor protein 1. (616 aa)
	NRAS	Uncharacterized protein. (189 aa)
	FNDC3A	Fibronectin type III domain containing 3A. (1175 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1323 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1182 aa)
	PTPN12	Protein tyrosine phosphatase non-receptor type 12. (789 aa)
	HRAS	HRas proto-oncogene, GTPase. (189 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	EREG	Epiregulin. (148 aa)
	CUL5	Cullin 5; Belongs to the cullin family. (780 aa)
	NRG2	Neuregulin 2. (540 aa)
	YES1	Tyrosine-protein kinase. (581 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSAPLP00000016792	Protein kinase domain-containing protein. (206 aa)
	PRKCE	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (743 aa)
	NRG1	Neuregulin 1. (685 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	ENSAPLP00000017981	Receptor protein-tyrosine kinase. (513 aa)
	ENSAPLP00000018348	Protein kinase domain-containing protein. (72 aa)
	PRKCA	Protein kinase C. (649 aa)
	CSDE1	Cold shock domain containing E1. (796 aa)
	MEMO1	Mediator of cell motility 1. (287 aa)
	NRG3	Neuregulin 3. (346 aa)
	RNF41	Ring finger protein 41. (317 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
	GAB1	GRB2 associated binding protein 1. (777 aa)
	BTC	EGF-like domain-containing protein. (417 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1317 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1169 aa)
	NRG4	Neuregulin 4. (115 aa)
	ENSAPLP00000030173	Uncharacterized protein. (328 aa)
	ENSAPLP00000030500	Protein kinase domain-containing protein. (80 aa)
	GRB2	Growth factor receptor bound protein 2. (203 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT3	ENSAPLP00000016229	ENSAPLP00000011266	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	ENSAPLP00000030173	ENSAPLP00000016229	ENSAPLP00000030173	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.432
AKT1	MATK	ENSAPLP00000016229	ENSAPLP00000002785	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.401
AKT1	PIK3CA	ENSAPLP00000016229	ENSAPLP00000012758	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.966
AKT1	PIK3R1	ENSAPLP00000016229	ENSAPLP00000017936	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 1.	0.944
AKT1	USP8	ENSAPLP00000016229	ENSAPLP00000001332	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.531
AKT1	YES1	ENSAPLP00000016229	ENSAPLP00000015074	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.462
AKT3	AKT1	ENSAPLP00000011266	ENSAPLP00000016229	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT3	MATK	ENSAPLP00000011266	ENSAPLP00000002785	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.401
AKT3	PIK3CA	ENSAPLP00000011266	ENSAPLP00000012758	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.976
AKT3	PIK3R1	ENSAPLP00000011266	ENSAPLP00000017936	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 1.	0.945
AKT3	USP8	ENSAPLP00000011266	ENSAPLP00000001332	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.521
AKT3	YES1	ENSAPLP00000011266	ENSAPLP00000015074	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.455
BTC	CSDE1	ENSAPLP00000027412	ENSAPLP00000021398	EGF-like domain-containing protein.	Cold shock domain containing E1.	0.405
BTC	EGF	ENSAPLP00000027412	ENSAPLP00000011666	EGF-like domain-containing protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.724
BTC	EGFR	ENSAPLP00000027412	ENSAPLP00000002564	EGF-like domain-containing protein.	Receptor protein-tyrosine kinase.	0.951
BTC	ENSAPLP00000017981	ENSAPLP00000027412	ENSAPLP00000017981	EGF-like domain-containing protein.	Receptor protein-tyrosine kinase.	0.539
BTC	ENSAPLP00000018348	ENSAPLP00000027412	ENSAPLP00000018348	EGF-like domain-containing protein.	Protein kinase domain-containing protein.	0.412
BTC	ENSAPLP00000030173	ENSAPLP00000027412	ENSAPLP00000030173	EGF-like domain-containing protein.	Uncharacterized protein.	0.440
BTC	ERBB4	ENSAPLP00000027412	ENSAPLP00000028809	EGF-like domain-containing protein.	Receptor protein-tyrosine kinase.	0.975