12 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1149 aa)
	EGFR	Receptor protein-tyrosine kinase. (1219 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	NRG2	Neuregulin 2. (540 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSAPLP00000016792	Protein kinase domain-containing protein. (206 aa)
	NRG1	Neuregulin 1. (685 aa)
	ENSAPLP00000017981	Receptor protein-tyrosine kinase. (513 aa)
	RNF41	Ring finger protein 41. (317 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	ENSAPLP00000030500	Protein kinase domain-containing protein. (80 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT3	ENSAPLP00000016229	ENSAPLP00000011266	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	USP8	ENSAPLP00000016229	ENSAPLP00000001332	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.531
AKT3	AKT1	ENSAPLP00000011266	ENSAPLP00000016229	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT3	USP8	ENSAPLP00000011266	ENSAPLP00000001332	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.521
EGFR	ENSAPLP00000023897	ENSAPLP00000002564	ENSAPLP00000023897	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.604
EGFR	NRG1	ENSAPLP00000002564	ENSAPLP00000017779	Receptor protein-tyrosine kinase.	Neuregulin 1.	0.880
EGFR	NRG2	ENSAPLP00000002564	ENSAPLP00000014937	Receptor protein-tyrosine kinase.	Neuregulin 2.	0.759
EGFR	RNF41	ENSAPLP00000002564	ENSAPLP00000023694	Receptor protein-tyrosine kinase.	Ring finger protein 41.	0.697
EGFR	RPS27A	ENSAPLP00000002564	ENSAPLP00000004982	Receptor protein-tyrosine kinase.	Ubiquitin-like domain-containing protein.	0.452
ENSAPLP00000016792	ENSAPLP00000030500	ENSAPLP00000016792	ENSAPLP00000030500	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.699
ENSAPLP00000016792	USP8	ENSAPLP00000016792	ENSAPLP00000001332	Protein kinase domain-containing protein.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.531
ENSAPLP00000017981	ENSAPLP00000023897	ENSAPLP00000017981	ENSAPLP00000023897	Receptor protein-tyrosine kinase.	Uncharacterized protein.	0.604
ENSAPLP00000017981	NRG1	ENSAPLP00000017981	ENSAPLP00000017779	Receptor protein-tyrosine kinase.	Neuregulin 1.	0.880
ENSAPLP00000017981	NRG2	ENSAPLP00000017981	ENSAPLP00000014937	Receptor protein-tyrosine kinase.	Neuregulin 2.	0.759
ENSAPLP00000017981	RNF41	ENSAPLP00000017981	ENSAPLP00000023694	Receptor protein-tyrosine kinase.	Ring finger protein 41.	0.697
ENSAPLP00000017981	RPS27A	ENSAPLP00000017981	ENSAPLP00000004982	Receptor protein-tyrosine kinase.	Ubiquitin-like domain-containing protein.	0.452
ENSAPLP00000023897	EGFR	ENSAPLP00000023897	ENSAPLP00000002564	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.604
ENSAPLP00000023897	ENSAPLP00000017981	ENSAPLP00000023897	ENSAPLP00000017981	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.604
ENSAPLP00000023897	NRG1	ENSAPLP00000023897	ENSAPLP00000017779	Uncharacterized protein.	Neuregulin 1.	0.539
ENSAPLP00000023897	NRG2	ENSAPLP00000023897	ENSAPLP00000014937	Uncharacterized protein.	Neuregulin 2.	0.539