(14 nodes) Apoptosis induced DNA fragmentation network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U3HZQ3_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (268 aa)
	HMGB2	High mobility group box 2. (207 aa)
	DFFB	DNA fragmentation factor subunit beta. (332 aa)
	KPNA1	Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
	DFFA	DNA fragmentation factor subunit alpha. (311 aa)
	KPNB1	Karyopherin subunit beta 1. (907 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (306 aa)
	HMGB3	High mobility group box 3. (341 aa)
	ENSAPLP00000020297	H15 domain-containing protein. (218 aa)
	ENSAPLP00000021206	DUF4203 domain-containing protein. (110 aa)
	HMGB1	High mobility group box 1. (281 aa)
	ENSAPLP00000030759	DUF4203 domain-containing protein. (244 aa)
	ENSAPLP00000031055	H15 domain-containing protein. (218 aa)
	H1-0	H1 histone family member 0. (194 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	DFFB	ENSAPLP00000015062	ENSAPLP00000002914	Caspase 3; Belongs to the peptidase C14A family.	DNA fragmentation factor subunit beta.	0.827
CASP3	KPNA1	ENSAPLP00000015062	ENSAPLP00000004462	Caspase 3; Belongs to the peptidase C14A family.	Importin subunit alpha; Belongs to the importin alpha family.	0.424
DFFB	CASP3	ENSAPLP00000002914	ENSAPLP00000015062	DNA fragmentation factor subunit beta.	Caspase 3; Belongs to the peptidase C14A family.	0.827
DFFB	ENSAPLP00000020297	ENSAPLP00000002914	ENSAPLP00000020297	DNA fragmentation factor subunit beta.	H15 domain-containing protein.	0.441
DFFB	ENSAPLP00000031055	ENSAPLP00000002914	ENSAPLP00000031055	DNA fragmentation factor subunit beta.	H15 domain-containing protein.	0.441
DFFB	H1-0	ENSAPLP00000002914	ENSAPLP00000031537	DNA fragmentation factor subunit beta.	H1 histone family member 0.	0.739
DFFB	U3HZQ3_ANAPP	ENSAPLP00000002914	ENSAPLP00000000473	DNA fragmentation factor subunit beta.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.709
ENSAPLP00000020297	DFFB	ENSAPLP00000020297	ENSAPLP00000002914	H15 domain-containing protein.	DNA fragmentation factor subunit beta.	0.441
ENSAPLP00000020297	H1-0	ENSAPLP00000020297	ENSAPLP00000031537	H15 domain-containing protein.	H1 histone family member 0.	0.451
ENSAPLP00000020297	KPNB1	ENSAPLP00000020297	ENSAPLP00000009979	H15 domain-containing protein.	Karyopherin subunit beta 1.	0.435
ENSAPLP00000031055	DFFB	ENSAPLP00000031055	ENSAPLP00000002914	H15 domain-containing protein.	DNA fragmentation factor subunit beta.	0.441
ENSAPLP00000031055	H1-0	ENSAPLP00000031055	ENSAPLP00000031537	H15 domain-containing protein.	H1 histone family member 0.	0.451
ENSAPLP00000031055	KPNB1	ENSAPLP00000031055	ENSAPLP00000009979	H15 domain-containing protein.	Karyopherin subunit beta 1.	0.435
H1-0	DFFB	ENSAPLP00000031537	ENSAPLP00000002914	H1 histone family member 0.	DNA fragmentation factor subunit beta.	0.739
H1-0	ENSAPLP00000020297	ENSAPLP00000031537	ENSAPLP00000020297	H1 histone family member 0.	H15 domain-containing protein.	0.451
H1-0	ENSAPLP00000031055	ENSAPLP00000031537	ENSAPLP00000031055	H1 histone family member 0.	H15 domain-containing protein.	0.451
H1-0	HMGB1	ENSAPLP00000031537	ENSAPLP00000023852	H1 histone family member 0.	High mobility group box 1.	0.421
H1-0	HMGB2	ENSAPLP00000031537	ENSAPLP00000002762	H1 histone family member 0.	High mobility group box 2.	0.421
H1-0	HMGB3	ENSAPLP00000031537	ENSAPLP00000016440	H1 histone family member 0.	High mobility group box 3.	0.421
H1-0	KPNB1	ENSAPLP00000031537	ENSAPLP00000009979	H1 histone family member 0.	Karyopherin subunit beta 1.	0.807