(35 nodes) Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7. (644 aa)
	ENSAPLP00000032387	Uncharacterized protein. (69 aa)
	PSTPIP2	Proline-serine-threonine phosphatase interacting protein 2. (319 aa)
	PSTPIP1	Proline-serine-threonine phosphatase interacting protein 1. (406 aa)
	ENSAPLP00000029820	RING-type domain-containing protein. (132 aa)
	TMEM189	TMEM189_B_dmain domain-containing protein. (411 aa)
	MAP2K6	Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (425 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (706 aa)
	BCL2L1	BCL2 like 1. (238 aa)
	ENSAPLP00000025287	Uncharacterized protein. (735 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (951 aa)
	UBE2V1	Ubiquitin conjugating enzyme E2 V1. (149 aa)
	ARRDC2	Arrestin_C domain-containing protein. (111 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	ENSAPLP00000018304	NDK domain-containing protein. (116 aa)
	ENSAPLP00000016785	Thioredoxin domain-containing protein. (258 aa)
	TAB1	TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (531 aa)
	BIRC7	Baculoviral IAP repeat containing 7. (440 aa)
	PANX1	Pannexin; Structural component of the gap junctions and the hemichannels. (576 aa)
	ARRDC1	Arrestin domain containing 1. (421 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (452 aa)
	ARRDC3	Arrestin domain containing 3. (414 aa)
	ARRDC4	Arrestin domain containing 4. (434 aa)
	U3IRD8_ANAPP	Uncharacterized protein. (934 aa)
	RNH1	Ribonuclease/angiogenin inhibitor 1. (436 aa)
	TXN	Thioredoxin; Belongs to the thioredoxin family. (105 aa)
	MAP3K20-2	SAM domain-containing protein. (549 aa)
	SUGT1	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (336 aa)
	TXNIP	Thioredoxin interacting protein. (390 aa)
	BIRC2	Uncharacterized protein. (611 aa)
	CASP2	Caspase 2; Belongs to the peptidase C14A family. (426 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	U3I785_ANAPP	Thioredoxin domain-containing protein. (145 aa)
	TAB3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (630 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (575 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRDC1	ENSAPLP00000016785	ENSAPLP00000013909	ENSAPLP00000016785	Arrestin domain containing 1.	Thioredoxin domain-containing protein.	0.495
ARRDC1	ENSAPLP00000018304	ENSAPLP00000013909	ENSAPLP00000018304	Arrestin domain containing 1.	NDK domain-containing protein.	0.495
ARRDC1	ENSAPLP00000025287	ENSAPLP00000013909	ENSAPLP00000025287	Arrestin domain containing 1.	Uncharacterized protein.	0.468
ARRDC1	TXN	ENSAPLP00000013909	ENSAPLP00000008437	Arrestin domain containing 1.	Thioredoxin; Belongs to the thioredoxin family.	0.706
ARRDC1	U3I785_ANAPP	ENSAPLP00000013909	ENSAPLP00000003106	Arrestin domain containing 1.	Thioredoxin domain-containing protein.	0.468
ARRDC1	U3IRD8_ANAPP	ENSAPLP00000013909	ENSAPLP00000009811	Arrestin domain containing 1.	Uncharacterized protein.	0.491
ARRDC2	ENSAPLP00000016785	ENSAPLP00000020343	ENSAPLP00000016785	Arrestin_C domain-containing protein.	Thioredoxin domain-containing protein.	0.495
ARRDC2	ENSAPLP00000018304	ENSAPLP00000020343	ENSAPLP00000018304	Arrestin_C domain-containing protein.	NDK domain-containing protein.	0.495
ARRDC2	ENSAPLP00000025287	ENSAPLP00000020343	ENSAPLP00000025287	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.468
ARRDC2	TXN	ENSAPLP00000020343	ENSAPLP00000008437	Arrestin_C domain-containing protein.	Thioredoxin; Belongs to the thioredoxin family.	0.706
ARRDC2	U3I785_ANAPP	ENSAPLP00000020343	ENSAPLP00000003106	Arrestin_C domain-containing protein.	Thioredoxin domain-containing protein.	0.468
ARRDC2	U3IRD8_ANAPP	ENSAPLP00000020343	ENSAPLP00000009811	Arrestin_C domain-containing protein.	Uncharacterized protein.	0.491
ARRDC3	ENSAPLP00000016785	ENSAPLP00000013151	ENSAPLP00000016785	Arrestin domain containing 3.	Thioredoxin domain-containing protein.	0.495
ARRDC3	ENSAPLP00000018304	ENSAPLP00000013151	ENSAPLP00000018304	Arrestin domain containing 3.	NDK domain-containing protein.	0.495
ARRDC3	ENSAPLP00000025287	ENSAPLP00000013151	ENSAPLP00000025287	Arrestin domain containing 3.	Uncharacterized protein.	0.468
ARRDC3	TXN	ENSAPLP00000013151	ENSAPLP00000008437	Arrestin domain containing 3.	Thioredoxin; Belongs to the thioredoxin family.	0.706
ARRDC3	U3I785_ANAPP	ENSAPLP00000013151	ENSAPLP00000003106	Arrestin domain containing 3.	Thioredoxin domain-containing protein.	0.468
ARRDC3	U3IRD8_ANAPP	ENSAPLP00000013151	ENSAPLP00000009811	Arrestin domain containing 3.	Uncharacterized protein.	0.491
ARRDC4	ENSAPLP00000016785	ENSAPLP00000009896	ENSAPLP00000016785	Arrestin domain containing 4.	Thioredoxin domain-containing protein.	0.495
ARRDC4	ENSAPLP00000018304	ENSAPLP00000009896	ENSAPLP00000018304	Arrestin domain containing 4.	NDK domain-containing protein.	0.495