STRINGSTRING
ENSAPLP00000024263 ENSAPLP00000024263 USP14 USP14 TLR5 TLR5 DNM1 DNM1 TIRAP TIRAP TLR6 TLR6 UNC93A UNC93A S100Z S100Z VWC2 VWC2 NKIRAS2 NKIRAS2 TAB3 TAB3 IRAK2 IRAK2 U3I8J0_ANAPP U3I8J0_ANAPP TLR7 TLR7 MAPK11 MAPK11 FGG FGG CD36 CD36 CD180 CD180 DNM3 DNM3 LY96 LY96 CREB5 CREB5 FADD FADD RPS27A RPS27A BIRC2 BIRC2 U3ICY7_ANAPP U3ICY7_ANAPP NKIRAS1 NKIRAS1 U3ID78_ANAPP U3ID78_ANAPP MAPK10 MAPK10 U3IEF6_ANAPP U3IEF6_ANAPP MAPK1 MAPK1 ITGAE ITGAE TRAF5 TRAF5 CREB1 CREB1 PPP4R1 PPP4R1 LRRC34 LRRC34 TANK TANK LGMN LGMN LRRC31 LRRC31 MAP3K20-2 MAP3K20-2 TBK1 TBK1 DUSP7 DUSP7 TLR3 TLR3 FOSL2 FOSL2 MAP3K8 MAP3K8 TLR-15 TLR-15 FBXW11 FBXW11 U3IR36_ANAPP U3IR36_ANAPP BPIFC BPIFC U3IS47_ANAPP U3IS47_ANAPP PLCG2 PLCG2 RPS6KA2 RPS6KA2 TLR2 TLR2 PPP4R4 PPP4R4 APOB APOB ATF1 ATF1 TLR4 TLR4 UNC93B1 UNC93B1 CTSK CTSK LRRC74A LRRC74A MAP2K4 MAP2K4 MAPK9 MAPK9 MAP3K20 MAP3K20 RPS6KA3 RPS6KA3 CTSL CTSL U3J3X4_ANAPP U3J3X4_ANAPP IKBKE IKBKE CASP8 CASP8 ITGB2 ITGB2 GSDME GSDME SKP1 SKP1 PTPN11 PTPN11 MAPKAPK2 MAPKAPK2 RIPK1 RIPK1 VWC2L VWC2L U3J954_ANAPP U3J954_ANAPP BIRC7 BIRC7 TAB1 TAB1 MBL2 MBL2 NFKB2 NFKB2 ENSAPLP00000017377 ENSAPLP00000017377 MAP2K3 MAP2K3 NLRC5 NLRC5 NFKB1 NFKB1 MAPK8 MAPK8 LRRC14 LRRC14 KXD1 KXD1 ENSAPLP00000018736 ENSAPLP00000018736 ENSAPLP00000018963 ENSAPLP00000018963 HSP90B1 HSP90B1 LY86 LY86 MAPK14 MAPK14 ENSAPLP00000019803 ENSAPLP00000019803 ATF2 ATF2 LRRC45 LRRC45 CUL1 CUL1 MAPKAPK3 MAPKAPK3 DUSP6 DUSP6 RPS6KA1 RPS6KA1 UBE2V1 UBE2V1 CCDC71L CCDC71L FOS FOS RELCH RELCH ENSAPLP00000023270 ENSAPLP00000023270 ENSAPLP00000023485 ENSAPLP00000023485 ATF7 ATF7 HMGB1 HMGB1 ENSAPLP00000023897 ENSAPLP00000023897 NOD1 NOD1 MAP3K7 MAP3K7 TRAF2 TRAF2 MAP3K1 MAP3K1 PTPN4 PTPN4 UBE2D2 UBE2D2 VRK3 VRK3 ENSAPLP00000026426 ENSAPLP00000026426 IRF7 IRF7 EEA1 EEA1 TRAF6 TRAF6 TAB2 TAB2 TRAF3 TRAF3 MAP2K6 MAP2K6 CTSB CTSB TMEM189 TMEM189 IKBKB IKBKB MAPK15 MAPK15 TICAM1 TICAM1 UBE2D3 UBE2D3 ENSAPLP00000031408 ENSAPLP00000031408 CNPY3 CNPY3 N4BP1 N4BP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSAPLP00000024263Uncharacterized protein. (1803 aa)
USP14Ubiquitin carboxyl-terminal hydrolase. (495 aa)
TLR5TIR domain-containing protein; Belongs to the Toll-like receptor family. (878 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (804 aa)
TIRAPTIR domain containing adaptor protein. (219 aa)
TLR6Toll like receptor 6; Belongs to the Toll-like receptor family. (818 aa)
UNC93AUnc-93 homolog A. (466 aa)
S100ZProtein S100; Belongs to the S-100 family. (99 aa)
VWC2Von Willebrand factor C domain containing 2. (331 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (191 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (630 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (731 aa)
U3I8J0_ANAPPUncharacterized protein. (1873 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
FGGFibrinogen gamma chain. (437 aa)
CD36CD36 molecule; Belongs to the CD36 family. (471 aa)
CD180CD180 molecule. (660 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (842 aa)
LY96Lymphocyte antigen 96. (155 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (501 aa)
FADDUncharacterized protein. (195 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
BIRC2Uncharacterized protein. (611 aa)
U3ICY7_ANAPPC-type lectin domain-containing protein. (199 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (191 aa)
U3ID78_ANAPPC-type lectin domain-containing protein. (200 aa)
MAPK10Mitogen-activated protein kinase. (384 aa)
U3IEF6_ANAPPUncharacterized protein. (1063 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
ITGAEIntegrin subunit alpha E; Belongs to the integrin alpha chain family. (1391 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (957 aa)
LRRC34Leucine rich repeat containing 34. (418 aa)
TANKTRAF family member associated NFKB activator. (481 aa)
LGMNLegumain. (431 aa)
LRRC31Leucine rich repeat containing 31. (582 aa)
MAP3K20-2SAM domain-containing protein. (549 aa)
TBK1TANK binding kinase 1. (600 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (914 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (323 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (487 aa)
TLR-15TIR domain-containing protein. (863 aa)
FBXW11F-box and WD repeat domain containing 11. (563 aa)
U3IR36_ANAPPS_100 domain-containing protein; Belongs to the S-100 family. (103 aa)
BPIFCBPI fold containing family C. (459 aa)
U3IS47_ANAPPUncharacterized protein. (355 aa)
PLCG2Phosphoinositide phospholipase C. (1086 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (888 aa)
APOBApolipoprotein B. (4563 aa)
ATF1Activating transcription factor 1. (318 aa)
TLR4Toll like receptor 4. (843 aa)
UNC93B1Uncharacterized protein. (654 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (311 aa)
LRRC74ALeucine rich repeat containing 74A. (481 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (409 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (452 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (711 aa)
CTSLUncharacterized protein; Belongs to the peptidase C1 family. (338 aa)
U3J3X4_ANAPPLRRCT domain-containing protein. (553 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (725 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (466 aa)
ITGB2Integrin beta. (773 aa)
GSDMEGasdermin E. (499 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
MAPKAPK2MAPK activated protein kinase 2. (397 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (229 aa)
U3J954_ANAPPTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (660 aa)
BIRC7Baculoviral IAP repeat containing 7. (440 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (531 aa)
MBL2Mannose binding lectin 2. (256 aa)
NFKB2Nuclear factor kappa B subunit 2. (845 aa)
ENSAPLP00000017377EF-hand domain-containing protein; Belongs to the S-100 family. (127 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (348 aa)
NLRC5NLR family CARD domain containing 5. (1891 aa)
NFKB1Nuclear factor kappa B subunit 1. (998 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
LRRC14Uncharacterized protein. (491 aa)
KXD1KxDL motif containing 1. (353 aa)
ENSAPLP00000018736WRNPLPNID domain-containing protein. (1006 aa)
ENSAPLP00000018963TIR domain-containing protein. (795 aa)
HSP90B1Heat shock protein 90 beta family member 1. (816 aa)
LY86Lymphocyte antigen 86. (161 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ENSAPLP00000019803Protein kinase domain-containing protein. (334 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (487 aa)
LRRC45Leucine rich repeat containing 45. (1126 aa)
CUL1Cullin 1; Belongs to the cullin family. (768 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (387 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa)
RPS6KA1Non-specific serine/threonine protein kinase. (892 aa)
UBE2V1Ubiquitin conjugating enzyme E2 V1. (149 aa)
CCDC71LCoiled-coil domain containing 71 like. (453 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (369 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1089 aa)
ENSAPLP00000023270Uncharacterized protein. (1671 aa)
ENSAPLP00000023485BPI2 domain-containing protein. (268 aa)
ATF7C2H2-type domain-containing protein. (114 aa)
HMGB1High mobility group box 1. (281 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (951 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (644 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1525 aa)
PTPN4Tyrosine-protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. (967 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
VRK3Uncharacterized protein. (597 aa)
ENSAPLP00000026426Protein kinase domain-containing protein. (144 aa)
IRF7Interferon regulatory factor 7. (523 aa)
EEA1Early endosome antigen 1. (1452 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (706 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (425 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (621 aa)
TMEM189TMEM189_B_dmain domain-containing protein. (411 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
MAPK15Mitogen-activated protein kinase. (604 aa)
TICAM1TRIF-NTD domain-containing protein. (507 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
ENSAPLP00000031408TIR domain-containing protein. (102 aa)
CNPY3Canopy FGF signaling regulator 3. (609 aa)
N4BP1NEDD4 binding protein 1. (931 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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