STRINGSTRING
SPRED1 SPRED1 PTBP2 PTBP2 SPRED2 SPRED2 FGFR2 FGFR2 POLR2E POLR2E FGF20 FGF20 ENSAPLP00000029569 ENSAPLP00000029569 ENSAPLP00000029488 ENSAPLP00000029488 POLR2H POLR2H FNDC3B FNDC3B FGFBP3 FGFBP3 ENSAPLP00000028132 ENSAPLP00000028132 POLR2D POLR2D GAB1 GAB1 FGF8 FGF8 FGFR4 FGFR4 PTBP1 PTBP1 FRS3 FRS3 MKNK1 MKNK1 ANOS1 ANOS1 FLRT3 FLRT3 ENSAPLP00000023897 ENSAPLP00000023897 POLR2L POLR2L MKNK2 MKNK2 FGF10 FGF10 ESRP2 ESRP2 CSDE1 CSDE1 POLR2B POLR2B FGFRL1 FGFRL1 RBFOX2 RBFOX2 PIK3R1 PIK3R1 FGF4 FGF4 POLR2K POLR2K ENSAPLP00000016895 ENSAPLP00000016895 FGF22 FGF22 NCBP1 NCBP1 U3J954_ANAPP U3J954_ANAPP KRAS KRAS PTPN11 PTPN11 BRAF BRAF POLR2F POLR2F U3J4B9_ANAPP U3J4B9_ANAPP FGFR1 FGFR1 ESRP1 ESRP1 U3J269_ANAPP U3J269_ANAPP GALNT3 GALNT3 CBL CBL U3IKP8_ANAPP U3IKP8_ANAPP SHC1 SHC1 TIAL1 TIAL1 NRAS NRAS FNDC3A FNDC3A TIA1 TIA1 FGF18 FGF18 STIL STIL HNRNPM HNRNPM SOS1 SOS1 FGF9 FGF9 KLB KLB SPRY2 SPRY2 HRAS HRAS PIK3CA PIK3CA FRS2 FRS2 FGF7 FGF7 FGF19 FGF19 POLR2J POLR2J FGF6 FGF6 FGF23 FGF23 FGFBP1 FGFBP1 FLRT2 FLRT2 FGF17 FGF17 FGF3 FGF3 GTF2F2 GTF2F2 PTBP3 PTBP3 RPS27A RPS27A POLR2C POLR2C FGF16 FGF16 FGF1 FGF1 FGF2 FGF2 FGFR3 FGFR3 GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPRED1Sprouty related EVH1 domain containing 1. (414 aa)
PTBP2Polypyrimidine tract binding protein 2. (578 aa)
SPRED2Sprouty related EVH1 domain containing 2. (450 aa)
FGFR2Fibroblast growth factor receptor. (843 aa)
POLR2ERNA polymerase II subunit E. (458 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (368 aa)
ENSAPLP00000029569Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (294 aa)
ENSAPLP00000029488Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (502 aa)
POLR2HRNA polymerase II subunit H. (95 aa)
FNDC3BFibronectin type III domain containing 3B. (1169 aa)
FGFBP3Fibroblast growth factor binding protein 3. (301 aa)
ENSAPLP00000028132Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (393 aa)
POLR2DRPOL4c domain-containing protein. (188 aa)
GAB1GRB2 associated binding protein 1. (777 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
FGFR4Fibroblast growth factor receptor. (910 aa)
PTBP1Polypyrimidine tract binding protein 1. (557 aa)
FRS3Fibroblast growth factor receptor substrate 3. (497 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (438 aa)
ANOS1Anosmin 1. (700 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (647 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
MKNK2MAPK interacting serine/threonine kinase 2. (286 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
ESRP2Epithelial splicing regulatory protein 2. (728 aa)
CSDE1Cold shock domain containing E1. (796 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1583 aa)
FGFRL1Fibroblast growth factor receptor like 1. (526 aa)
RBFOX2RNA binding fox-1 homolog 2. (490 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
ENSAPLP00000016895Uncharacterized protein. (72 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (367 aa)
NCBP1Nuclear cap binding protein subunit 1. (793 aa)
U3J954_ANAPPTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (660 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (755 aa)
POLR2FRNA polymerase II subunit F. (291 aa)
U3J4B9_ANAPPNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
FGFR1Fibroblast growth factor receptor. (813 aa)
ESRP1Epithelial splicing regulatory protein 1. (610 aa)
U3J269_ANAPPNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (195 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (632 aa)
CBLCbl proto-oncogene. (814 aa)
U3IKP8_ANAPPUncharacterized protein. (1110 aa)
SHC1SHC adaptor protein 1. (616 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (350 aa)
NRASUncharacterized protein. (189 aa)
FNDC3AFibronectin type III domain containing 3A. (1175 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (383 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (276 aa)
STILSTIL centriolar assembly protein. (1301 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (685 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1323 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
KLBKlotho beta. (1006 aa)
SPRY2Sprouty RTK signaling antagonist 2. (309 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (226 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (182 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (270 aa)
FGFBP1Fibroblast growth factor binding protein 1. (211 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (662 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (262 aa)
PTBP3Polypyrimidine tract binding protein 3. (551 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (230 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (105 aa)
FGFR3Fibroblast growth factor receptor. (833 aa)
GRB2Growth factor receptor bound protein 2. (203 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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