83 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRIO	Trio Rho guanine nucleotide exchange factor. (2201 aa)
	KXD1	KxDL motif containing 1. (353 aa)
	ARHGEF5	Uncharacterized protein. (1542 aa)
	NET1	Neuroepithelial cell transforming 1. (591 aa)
	MAPK8	Mitogen-activated protein kinase. (384 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (998 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
	NGF	Nerve growth factor; Belongs to the NGF-beta family. (293 aa)
	ARHGEF39	Rho guanine nucleotide exchange factor 39. (437 aa)
	ARHGEF18	Uncharacterized protein. (1015 aa)
	FGD3	FYVE, RhoGEF and PH domain containing 3. (712 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1548 aa)
	NCSTN	Nicastrin. (719 aa)
	NGEF	Uncharacterized protein. (741 aa)
	U3J0U5_ANAPP	DH domain-containing protein. (376 aa)
	ARHGEF26	Rho guanine nucleotide exchange factor 26. (843 aa)
	GSAP	Gamma-secretase activating protein. (846 aa)
	ECT2	Epithelial cell transforming 2. (914 aa)
	ENSAPLP00000019469	Uncharacterized protein. (318 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1432 aa)
	AKAP13	A-kinase anchoring protein 13. (2774 aa)
	LINGO1	Leucine rich repeat and Ig domain containing 1. (792 aa)
	NGFR	Uncharacterized protein. (181 aa)
	CCDC71L	Coiled-coil domain containing 71 like. (453 aa)
	ENSAPLP00000022326	Uncharacterized protein. (263 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
	ARHGEF4	Uncharacterized protein. (2294 aa)
	TIAM2	T cell lymphoma invasion and metastasis 2. (1724 aa)
	ENSAPLP00000023562	Protein kinase domain-containing protein. (98 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (854 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	MCF2L	MCF.2 cell line derived transforming sequence like. (1189 aa)
	OBSL1	Obscurin like 1. (2172 aa)
	ENSAPLP00000024412	Death domain-containing protein. (197 aa)
	ABR	Rho-GAP domain-containing protein. (155 aa)
	ENSAPLP00000024578	Uncharacterized protein. (635 aa)
	ENSAPLP00000025444	DH domain-containing protein. (1335 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (790 aa)
	ENSAPLP00000025878	Uncharacterized protein. (339 aa)
	ARHGEF33	Rho guanine nucleotide exchange factor 33. (825 aa)
	VAV1	Calponin-homology (CH) domain-containing protein. (81 aa)
	FGD2	FYVE, RhoGEF and PH domain containing 2. (624 aa)
	TGM6	Transglutaminase 6. (713 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	MCF2	MCF.2 cell line derived transforming sequence. (1149 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
	SQSTM1	Uncharacterized protein. (77 aa)
	FGD4	FYVE, RhoGEF and PH domain containing 4. (1113 aa)
	ITGB3BP	Integrin subunit beta 3 binding protein. (192 aa)
	ENSAPLP00000029278	DH domain-containing protein. (269 aa)
	PSEN2	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
	ARHGEF3	Rho guanine nucleotide exchange factor 3. (673 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
	ENSAPLP00000030426	DH domain-containing protein. (255 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1662 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (843 aa)
	LINGO2	Leucine rich repeat and Ig domain containing 2. (606 aa)
	ARHGDIA	Rho GDP dissociation inhibitor alpha. (277 aa)
	PLEKHG5	Pleckstrin homology and RhoGEF domain containing G5. (489 aa)
	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor 6. (731 aa)
	ARHGEF17	Uncharacterized protein. (672 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
	MCF2L2	MCF.2 cell line derived transforming sequence-like 2. (836 aa)
	ADAM17	ADAM metallopeptidase domain 17. (836 aa)
	ITSN1	Intersectin 1. (1712 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (552 aa)
	RASGRF2	Ras protein specific guanine nucleotide releasing factor 2. (1238 aa)
	KALRN	Kalirin RhoGEF kinase. (2922 aa)
	AATF	Apoptosis antagonizing transcription factor. (560 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	U3IBK2_ANAPP	Uncharacterized protein. (566 aa)
	CASP2	Caspase 2; Belongs to the peptidase C14A family. (426 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (513 aa)
	SESTD1	SEC14 and spectrin domain containing 1. (695 aa)
	OMG	Oligodendrocyte myelin glycoprotein. (428 aa)
	U3HZQ3_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (268 aa)
	ENSAPLP00000018970	TGc domain-containing protein. (695 aa)
	ARHGEF11	RGS domain-containing protein. (576 aa)
	ARHGEF38	Rho guanine nucleotide exchange factor 38. (882 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1323 aa)
	ARHGEF37	Rho guanine nucleotide exchange factor 37. (686 aa)
	U3IRT3_ANAPP	TGc domain-containing protein. (653 aa)
	PRDM4	PR/SET domain 4. (828 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AATF	RPS27A	ENSAPLP00000005950	ENSAPLP00000004982	Apoptosis antagonizing transcription factor.	Ubiquitin-like domain-containing protein.	0.527
ADAM17	ENSAPLP00000024412	ENSAPLP00000007402	ENSAPLP00000024412	ADAM metallopeptidase domain 17.	Death domain-containing protein.	0.607
ADAM17	NCSTN	ENSAPLP00000007402	ENSAPLP00000014633	ADAM metallopeptidase domain 17.	Nicastrin.	0.603
ADAM17	PSEN1	ENSAPLP00000007402	ENSAPLP00000018025	ADAM metallopeptidase domain 17.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.602
ADAM17	PSEN2	ENSAPLP00000007402	ENSAPLP00000029357	ADAM metallopeptidase domain 17.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.602
AKAP13	ECT2	ENSAPLP00000020842	ENSAPLP00000019266	A-kinase anchoring protein 13.	Epithelial cell transforming 2.	0.459
AKAP13	ITSN1	ENSAPLP00000020842	ENSAPLP00000006872	A-kinase anchoring protein 13.	Intersectin 1.	0.420
AKAP13	MCF2	ENSAPLP00000020842	ENSAPLP00000027948	A-kinase anchoring protein 13.	MCF.2 cell line derived transforming sequence.	0.416
ARHGDIA	ENSAPLP00000024412	ENSAPLP00000031946	ENSAPLP00000024412	Rho GDP dissociation inhibitor alpha.	Death domain-containing protein.	0.723
ARHGDIA	NGFR	ENSAPLP00000031946	ENSAPLP00000021925	Rho GDP dissociation inhibitor alpha.	Uncharacterized protein.	0.631
ARHGEF11	ARHGEF17	ENSAPLP00000010461	ENSAPLP00000008151	RGS domain-containing protein.	Uncharacterized protein.	0.455
ARHGEF11	ECT2	ENSAPLP00000010461	ENSAPLP00000019266	RGS domain-containing protein.	Epithelial cell transforming 2.	0.515
ARHGEF11	ENSAPLP00000030426	ENSAPLP00000010461	ENSAPLP00000030426	RGS domain-containing protein.	DH domain-containing protein.	0.925
ARHGEF11	ITSN1	ENSAPLP00000010461	ENSAPLP00000006872	RGS domain-containing protein.	Intersectin 1.	0.424
ARHGEF12	ARHGEF17	ENSAPLP00000014871	ENSAPLP00000008151	Rho guanine nucleotide exchange factor 12.	Uncharacterized protein.	0.455
ARHGEF12	ARHGEF18	ENSAPLP00000014871	ENSAPLP00000015636	Rho guanine nucleotide exchange factor 12.	Uncharacterized protein.	0.402
ARHGEF12	ARHGEF7	ENSAPLP00000014871	ENSAPLP00000031368	Rho guanine nucleotide exchange factor 12.	Rho guanine nucleotide exchange factor 7.	0.936
ARHGEF12	ECT2	ENSAPLP00000014871	ENSAPLP00000019266	Rho guanine nucleotide exchange factor 12.	Epithelial cell transforming 2.	0.515
ARHGEF12	ITSN1	ENSAPLP00000014871	ENSAPLP00000006872	Rho guanine nucleotide exchange factor 12.	Intersectin 1.	0.424
ARHGEF17	ARHGEF11	ENSAPLP00000008151	ENSAPLP00000010461	Uncharacterized protein.	RGS domain-containing protein.	0.455