69 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U3I327_ANAPP	MHC_II_beta domain-containing protein. (97 aa)
	ZAP70	Tyrosine-protein kinase. (607 aa)
	BCL10	CARD domain-containing protein. (316 aa)
	PIK3CB	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	CARD11	Caspase recruitment domain family member 11. (1187 aa)
	PAG1	Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (427 aa)
	U3IB91_ANAPP	MHC_II_beta domain-containing protein. (118 aa)
	U3IBD7_ANAPP	MHC_II_beta domain-containing protein. (126 aa)
	U3IBK2_ANAPP	Uncharacterized protein. (566 aa)
	HLA-DRA	Major histocompatibility complex, class II, DR alpha. (255 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	U3IGS0_ANAPP	Protein kinase domain-containing protein. (282 aa)
	RIPK2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (552 aa)
	PLCG1	Phosphoinositide phospholipase C. (502 aa)
	U3IJ46_ANAPP	Ig-like domain-containing protein. (180 aa)
	U3IJ66_ANAPP	Ig-like domain-containing protein. (203 aa)
	PSMA1	Proteasome subunit alpha type. (259 aa)
	MAP3K20-2	SAM domain-containing protein. (549 aa)
	PSME4	BLM10_mid domain-containing protein. (581 aa)
	FYB1	FYN binding protein 1. (706 aa)
	U3IN59_ANAPP	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1295 aa)
	GRAP2	GRB2 related adaptor protein 2. (323 aa)
	FBXW11	F-box and WD repeat domain containing 11. (563 aa)
	MALT1	MALT1 paracaspase. (816 aa)
	U3ISR2_ANAPP	Ig_4 domain-containing protein. (316 aa)
	CD3E	CD3e molecule. (187 aa)
	PLCG2	Phosphoinositide phospholipase C. (1086 aa)
	PIK3R2	Uncharacterized protein. (731 aa)
	PTPN22	Protein tyrosine phosphatase non-receptor type 22. (803 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	TRAT1	T cell receptor associated transmembrane adaptor 1. (151 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (945 aa)
	MAP3K20	Mitogen-activated protein kinase kinase kinase 20. (452 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (191 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
	PAK2	CRIB domain-containing protein. (161 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (556 aa)
	ENSAPLP00000017028	Uncharacterized protein. (118 aa)
	ENSAPLP00000017596	MHC_II_beta domain-containing protein. (133 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	CD4	Ig-like domain-containing protein. (264 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (998 aa)
	ENSAPLP00000018531	DUF1968 domain-containing protein. (178 aa)
	KXD1	KxDL motif containing 1. (353 aa)
	PAK1	CRIB domain-containing protein. (170 aa)
	ENSAPLP00000020183	Phosphoinositide phospholipase C. (424 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (768 aa)
	ENSAPLP00000021459	Uncharacterized protein. (188 aa)
	UBE2V1	Ubiquitin conjugating enzyme E2 V1. (149 aa)
	CCDC71L	Coiled-coil domain containing 71 like. (453 aa)
	INPP5D	SH2 domain-containing protein. (1260 aa)
	ENSAPLP00000022617	Uncharacterized protein. (721 aa)
	ENSAPLP00000022634	MHC_II_beta domain-containing protein. (123 aa)
	U3IJ33_ANAPP	Uncharacterized protein. (143 aa)
	PAK3	Non-specific serine/threonine protein kinase. (562 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7. (644 aa)
	SPNS3	Sphingolipid transporter 3 (putative). (526 aa)
	ENSAPLP00000026079	DUF3437 domain-containing protein. (220 aa)
	ENSAPLP00000026803	Ig-like domain-containing protein. (135 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	ENSAPLP00000027970	MHC_II_beta domain-containing protein. (146 aa)
	CD247	CD247 molecule. (167 aa)
	TAB2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (706 aa)
	ENSAPLP00000029181	Ig-like domain-containing protein. (158 aa)
	ENSAPLP00000030900	Ig-like domain-containing protein. (174 aa)
	CDC34	Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (94 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL10	CARD11	ENSAPLP00000002985	ENSAPLP00000003269	CARD domain-containing protein.	Caspase recruitment domain family member 11.	0.948
BCL10	ENSAPLP00000022617	ENSAPLP00000002985	ENSAPLP00000022617	CARD domain-containing protein.	Uncharacterized protein.	0.994
BCL10	ENSAPLP00000023897	ENSAPLP00000002985	ENSAPLP00000023897	CARD domain-containing protein.	Uncharacterized protein.	0.430
BCL10	MALT1	ENSAPLP00000002985	ENSAPLP00000009828	CARD domain-containing protein.	MALT1 paracaspase.	0.999
BCL10	MAP3K20	ENSAPLP00000002985	ENSAPLP00000013782	CARD domain-containing protein.	Mitogen-activated protein kinase kinase kinase 20.	0.455
BCL10	MAP3K20-2	ENSAPLP00000002985	ENSAPLP00000008016	CARD domain-containing protein.	SAM domain-containing protein.	0.455
BCL10	MAP3K7	ENSAPLP00000002985	ENSAPLP00000024103	CARD domain-containing protein.	Mitogen-activated protein kinase kinase kinase 7.	0.600
BCL10	NFKB1	ENSAPLP00000002985	ENSAPLP00000018425	CARD domain-containing protein.	Nuclear factor kappa B subunit 1.	0.443
BCL10	RIPK2	ENSAPLP00000002985	ENSAPLP00000006481	CARD domain-containing protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.517
BCL10	RPS27A	ENSAPLP00000002985	ENSAPLP00000004982	CARD domain-containing protein.	Ubiquitin-like domain-containing protein.	0.471
BCL10	TAB2	ENSAPLP00000002985	ENSAPLP00000028451	CARD domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.631
BCL10	TRAF6	ENSAPLP00000002985	ENSAPLP00000027926	CARD domain-containing protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.789
BCL10	UBE2V1	ENSAPLP00000002985	ENSAPLP00000021756	CARD domain-containing protein.	Ubiquitin conjugating enzyme E2 V1.	0.897
BCL10	ZAP70	ENSAPLP00000002985	ENSAPLP00000001899	CARD domain-containing protein.	Tyrosine-protein kinase.	0.420
CARD11	BCL10	ENSAPLP00000003269	ENSAPLP00000002985	Caspase recruitment domain family member 11.	CARD domain-containing protein.	0.948
CARD11	ENSAPLP00000022617	ENSAPLP00000003269	ENSAPLP00000022617	Caspase recruitment domain family member 11.	Uncharacterized protein.	0.854
CARD11	MALT1	ENSAPLP00000003269	ENSAPLP00000009828	Caspase recruitment domain family member 11.	MALT1 paracaspase.	0.980
CARD11	MAP3K20	ENSAPLP00000003269	ENSAPLP00000013782	Caspase recruitment domain family member 11.	Mitogen-activated protein kinase kinase kinase 20.	0.546
CARD11	MAP3K20-2	ENSAPLP00000003269	ENSAPLP00000008016	Caspase recruitment domain family member 11.	SAM domain-containing protein.	0.546
CARD11	MAP3K7	ENSAPLP00000003269	ENSAPLP00000024103	Caspase recruitment domain family member 11.	Mitogen-activated protein kinase kinase kinase 7.	0.802