STRINGSTRING
GNG7 GNG7 FZD6 FZD6 PRICKLE4 PRICKLE4 GNG12 GNG12 GNB3 GNB3 FZD8 FZD8 TCF7L2 TCF7L2 WDR92 WDR92 FZD4 FZD4 GNG10 GNG10 CLTC CLTC FZD5 FZD5 TCF7 TCF7 ENSAPLP00000032903 ENSAPLP00000032903 GNG5 GNG5 FZD7 FZD7 FHDC1 FHDC1 FZD2 FZD2 PLCB2 PLCB2 NLK NLK PRICKLE1 PRICKLE1 PPP3CB PPP3CB GNG4 GNG4 FZD1 FZD1 AP2M1 AP2M1 LEF1 LEF1 NFAT5 NFAT5 PSMA1 PSMA1 MAP3K20-2 MAP3K20-2 U3ILH3_ANAPP U3ILH3_ANAPP PSME4 PSME4 WNT11 WNT11 PDE6B PDE6B GNB1 GNB1 GNG13 GNG13 WNT5A WNT5A GNB4 GNB4 GNGT2 GNGT2 PLCB1 PLCB1 PSMA7 PSMA7 CTNNB1 CTNNB1 PSMD1 PSMD1 MAP3K20 MAP3K20 PDE6C PDE6C FZD3 FZD3 PSMD10 PSMD10 PDE6G PDE6G PSMC1 PSMC1 ENSAPLP00000016947 ENSAPLP00000016947 GNB5 GNB5 AP2A2 AP2A2 SYNPO SYNPO PPP3CC PPP3CC PPP3CA PPP3CA KXD1 KXD1 CLTA CLTA ENSAPLP00000019563 ENSAPLP00000019563 AP2B1 AP2B1 PDE6H PDE6H ENSAPLP00000021459 ENSAPLP00000021459 TCF7L1 TCF7L1 GNG11 GNG11 ROR2 ROR2 ENSAPLP00000024089 ENSAPLP00000024089 MAP3K7 MAP3K7 NFATC1 NFATC1 PRICKLE2 PRICKLE2 ROR1 ROR1 GNG2 GNG2 ENSAPLP00000026079 ENSAPLP00000026079 WNT1 WNT1 PPP3R1 PPP3R1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (890 aa)
PRICKLE4Uncharacterized protein. (283 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNB3G protein subunit beta 3. (331 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (682 aa)
TCF7L2Transcription factor 7 like 2. (574 aa)
WDR92WD repeat domain 92. (361 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1676 aa)
FZD5Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)
TCF7Transcription factor 7. (439 aa)
ENSAPLP00000032903HMG box domain-containing protein. (180 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (176 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (573 aa)
FHDC1FH2 domain containing 1. (1138 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
NLKMitogen-activated protein kinase. (435 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
PPP3CBSerine/threonine-protein phosphatase. (510 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (556 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (429 aa)
LEF1Uncharacterized protein. (415 aa)
NFAT5Nuclear factor of activated T cells 5. (1462 aa)
PSMA1Proteasome subunit alpha type. (259 aa)
MAP3K20-2SAM domain-containing protein. (549 aa)
U3ILH3_ANAPPProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
PSME4BLM10_mid domain-containing protein. (581 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
PDE6BPhosphodiesterase. (836 aa)
GNB1G protein subunit beta 1. (372 aa)
GNG13G protein subunit gamma 13. (67 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
GNB4G protein subunit beta 4. (343 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1082 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
CTNNB1Catenin beta 1. (781 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (945 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (452 aa)
PDE6CPhosphodiesterase. (863 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (191 aa)
PDE6GPhosphodiesterase 6G. (87 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
ENSAPLP00000016947FH2 domain-containing protein. (278 aa)
GNB5G protein subunit beta 5. (401 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
SYNPOSynaptopodin. (1131 aa)
PPP3CCSerine/threonine-protein phosphatase. (507 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
KXD1KxDL motif containing 1. (353 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (247 aa)
ENSAPLP00000019563annotation not available (178 aa)
AP2B1AP complex subunit beta. (951 aa)
PDE6HPhosphodiesterase 6H. (85 aa)
ENSAPLP00000021459Uncharacterized protein. (188 aa)
TCF7L1Uncharacterized protein. (415 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa)
ENSAPLP00000024089Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (163 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (644 aa)
NFATC1Nuclear factor of activated T cells 1. (907 aa)
PRICKLE2Prickle planar cell polarity protein 2. (881 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (942 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
ENSAPLP00000026079DUF3437 domain-containing protein. (220 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (508 aa)
PPP3R1Uncharacterized protein. (170 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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