77 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNG5	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (176 aa)
	SESTD1	SEC14 and spectrin domain containing 1. (695 aa)
	ADRA1D	Adrenoceptor alpha 1D; Belongs to the G-protein coupled receptor 1 family. (270 aa)
	GNB3	G protein subunit beta 3. (331 aa)
	GNA12	G protein subunit alpha 12. (385 aa)
	ARHGEF9	Cdc42 guanine nucleotide exchange factor 9. (513 aa)
	PLXNB2	Plexin B2. (1845 aa)
	GNG4	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
	KALRN	Kalirin RhoGEF kinase. (2922 aa)
	RASGRF2	Ras protein specific guanine nucleotide releasing factor 2. (1238 aa)
	ITSN1	Intersectin 1. (1712 aa)
	ADRA1A	Adrenoceptor alpha 1A. (442 aa)
	MCF2L2	MCF.2 cell line derived transforming sequence-like 2. (836 aa)
	ARHGEF17	Uncharacterized protein. (672 aa)
	PLXNB1	Plexin B1. (2107 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor. (2201 aa)
	U3IRT3_ANAPP	TGc domain-containing protein. (653 aa)
	ARHGEF37	Rho guanine nucleotide exchange factor 37. (686 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1323 aa)
	ARHGEF38	Rho guanine nucleotide exchange factor 38. (882 aa)
	ARHGEF11	RGS domain-containing protein. (576 aa)
	GNB1	G protein subunit beta 1. (372 aa)
	ARHGEF33	Rho guanine nucleotide exchange factor 33. (825 aa)
	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor 6. (731 aa)
	GNG13	G protein subunit gamma 13. (67 aa)
	GNB4	G protein subunit beta 4. (343 aa)
	ARHGEF26	Rho guanine nucleotide exchange factor 26. (843 aa)
	GNGT2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
	U3J0U5_ANAPP	DH domain-containing protein. (376 aa)
	NGEF	Uncharacterized protein. (741 aa)
	RHOA	Ras homolog family member A. (193 aa)
	ARHGEF12	Rho guanine nucleotide exchange factor 12. (1548 aa)
	FGD3	FYVE, RhoGEF and PH domain containing 3. (712 aa)
	ARHGEF18	Uncharacterized protein. (1015 aa)
	GNB5	G protein subunit beta 5. (401 aa)
	ADRA1B	Adrenoceptor alpha 1B. (521 aa)
	NET1	Neuroepithelial cell transforming 1. (591 aa)
	ARHGEF5	Uncharacterized protein. (1542 aa)
	ENSAPLP00000018970	TGc domain-containing protein. (695 aa)
	ARHGEF39	Rho guanine nucleotide exchange factor 39. (437 aa)
	RHOC	Uncharacterized protein. (280 aa)
	ECT2	Epithelial cell transforming 2. (914 aa)
	ENSAPLP00000019469	Uncharacterized protein. (318 aa)
	RHOB	Ras homolog family member B. (196 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1432 aa)
	AKAP13	A-kinase anchoring protein 13. (2774 aa)
	ENSAPLP00000022326	Uncharacterized protein. (263 aa)
	GNG11	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	SOS2	SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
	ARHGEF4	Uncharacterized protein. (2294 aa)
	TIAM2	T cell lymphoma invasion and metastasis 2. (1724 aa)
	ENSAPLP00000023562	Protein kinase domain-containing protein. (98 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (854 aa)
	MCF2L	MCF.2 cell line derived transforming sequence like. (1189 aa)
	OBSL1	Obscurin like 1. (2172 aa)
	ABR	Rho-GAP domain-containing protein. (155 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	ENSAPLP00000025444	DH domain-containing protein. (1335 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (790 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
	ENSAPLP00000025878	Uncharacterized protein. (339 aa)
	VAV1	Calponin-homology (CH) domain-containing protein. (81 aa)
	FGD2	FYVE, RhoGEF and PH domain containing 2. (624 aa)
	TGM6	Transglutaminase 6. (713 aa)
	MCF2	MCF.2 cell line derived transforming sequence. (1149 aa)
	GNG7	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
	FGD4	FYVE, RhoGEF and PH domain containing 4. (1113 aa)
	ENSAPLP00000029278	DH domain-containing protein. (269 aa)
	ARHGEF3	Rho guanine nucleotide exchange factor 3. (673 aa)
	ROCK2	Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1488 aa)
	GNG12	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
	ENSAPLP00000030426	DH domain-containing protein. (255 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1662 aa)
	ARHGEF7	Rho guanine nucleotide exchange factor 7. (843 aa)
	GNG10	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
	PLEKHG5	Pleckstrin homology and RhoGEF domain containing G5. (489 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABR	RHOA	ENSAPLP00000024448	ENSAPLP00000014536	Rho-GAP domain-containing protein.	Ras homolog family member A.	0.470
ABR	RHOB	ENSAPLP00000024448	ENSAPLP00000019696	Rho-GAP domain-containing protein.	Ras homolog family member B.	0.468
ABR	RHOC	ENSAPLP00000024448	ENSAPLP00000019250	Rho-GAP domain-containing protein.	Uncharacterized protein.	0.470
ADRA1A	ADRA1B	ENSAPLP00000007056	ENSAPLP00000017731	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1B.	0.417
ADRA1A	ADRA1D	ENSAPLP00000007056	ENSAPLP00000002578	Adrenoceptor alpha 1A.	Adrenoceptor alpha 1D; Belongs to the G-protein coupled receptor 1 family.	0.409
ADRA1A	ARHGEF11	ENSAPLP00000007056	ENSAPLP00000010461	Adrenoceptor alpha 1A.	RGS domain-containing protein.	0.421
ADRA1A	ARHGEF12	ENSAPLP00000007056	ENSAPLP00000014871	Adrenoceptor alpha 1A.	Rho guanine nucleotide exchange factor 12.	0.688
ADRA1A	ENSAPLP00000023562	ENSAPLP00000007056	ENSAPLP00000023562	Adrenoceptor alpha 1A.	Protein kinase domain-containing protein.	0.412
ADRA1A	ENSAPLP00000030426	ENSAPLP00000007056	ENSAPLP00000030426	Adrenoceptor alpha 1A.	DH domain-containing protein.	0.421
ADRA1A	GNA12	ENSAPLP00000007056	ENSAPLP00000003108	Adrenoceptor alpha 1A.	G protein subunit alpha 12.	0.605
ADRA1A	GNA13	ENSAPLP00000007056	ENSAPLP00000024986	Adrenoceptor alpha 1A.	G protein subunit alpha 13.	0.605
ADRA1A	GNB1	ENSAPLP00000007056	ENSAPLP00000010816	Adrenoceptor alpha 1A.	G protein subunit beta 1.	0.511
ADRA1A	GNB3	ENSAPLP00000007056	ENSAPLP00000002795	Adrenoceptor alpha 1A.	G protein subunit beta 3.	0.511
ADRA1A	GNB4	ENSAPLP00000007056	ENSAPLP00000012022	Adrenoceptor alpha 1A.	G protein subunit beta 4.	0.511
ADRA1A	GNB5	ENSAPLP00000007056	ENSAPLP00000016983	Adrenoceptor alpha 1A.	G protein subunit beta 5.	0.654
ADRA1A	GNG10	ENSAPLP00000007056	ENSAPLP00000031667	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.581
ADRA1A	GNG11	ENSAPLP00000007056	ENSAPLP00000022549	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.507
ADRA1A	GNG12	ENSAPLP00000007056	ENSAPLP00000029962	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.471
ADRA1A	GNG13	ENSAPLP00000007056	ENSAPLP00000011608	Adrenoceptor alpha 1A.	G protein subunit gamma 13.	0.581
ADRA1A	GNG2	ENSAPLP00000007056	ENSAPLP00000025803	Adrenoceptor alpha 1A.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.530