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| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (506 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (463 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | CCND1 | Cyclin_C domain-containing protein. (153 aa) |
| | CABLES2 | Cdk5 and Abl enzyme substrate 2. (534 aa) |
| | ENSAPLP00000018736 | WRNPLPNID domain-containing protein. (1006 aa) |
| | KXD1 | KxDL motif containing 1. (353 aa) |
| | SKP2 | S-phase kinase associated protein 2. (671 aa) |
| | E2F4 | E2F_TDP domain-containing protein. (97 aa) |
| | ENSAPLP00000016792 | Protein kinase domain-containing protein. (206 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (830 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | E2F5 | E2F transcription factor 5. (359 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (376 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | TM4SF19 | Uncharacterized protein. (258 aa) |
| | RBBP8NL | RBBP8 N-terminal like. (681 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (112 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (191 aa) |
| | TFDP1 | Transcription factor. (412 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (945 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (384 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (559 aa) |
| | WEE2 | Wee1-like protein kinase. (605 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (83 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (810 aa) |
| | GMNN | Uncharacterized protein. (407 aa) |
| | PPP2R3B | Uncharacterized protein. (580 aa) |
| | PSMB1 | Proteasome subunit beta. (238 aa) |
| | E2F1 | E2F transcription factor 1. (388 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (430 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (756 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (888 aa) |
| | ORC3 | Origin recognition complex subunit 3. (682 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (457 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2285 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (663 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (255 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (339 aa) |
| | FNDC3A | Fibronectin type III domain containing 3A. (1175 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (270 aa) |
| | POLA1 | DNA polymerase. (1490 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (392 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (820 aa) |
| | MEIOB | Meiosis specific with OB-fold. (476 aa) |
| | CDC25A | Cell division cycle 25A. (434 aa) |
| | U3IKP8_ANAPP | Uncharacterized protein. (1110 aa) |
| | MNAT1 | MNAT1 component of CDK activating kinase. (336 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (422 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (828 aa) |
| | PSMA1 | Proteasome subunit alpha type. (259 aa) |
| | RB1 | RB transcriptional corepressor 1. (855 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (405 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (957 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (833 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (353 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (300 aa) |
| | LYN | Tyrosine-protein kinase. (535 aa) |
| | E2F3 | E2F_CC-MB domain-containing protein. (226 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (323 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | MYBL2 | MYB proto-oncogene like 2. (723 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (390 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (889 aa) |
| | DBF4 | DBF4 zinc finger. (705 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (869 aa) |
| | PSMB3 | Proteasome subunit beta 3. (172 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (508 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (861 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (389 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (344 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PPP2R3A | EF-hand domain-containing protein. (1090 aa) |
| | RPA2 | Replication protein A2. (269 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | U3I2I6_ANAPP | Protein kinase domain-containing protein. (184 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (343 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1176 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa) |
| | PSMA2 | Proteasome endopeptidase complex. (475 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (150 aa) |
| | CDKN1C | Uncharacterized protein. (311 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (57 aa) |
| | CDC45 | Cell division cycle 45. (566 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (768 aa) |
| | PSMA5 | Proteasome subunit alpha 5. (169 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (371 aa) |
| | ENSAPLP00000021459 | Uncharacterized protein. (188 aa) |
| | ENSAPLP00000021506 | PDZ domain-containing protein. (214 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (187 aa) |
| | PRR5L | Proline rich 5 like. (366 aa) |
| | CDC7 | Uncharacterized protein. (166 aa) |
| | E2F2 | E2F transcription factor 2. (369 aa) |
| | ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase. (610 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | ENSAPLP00000023122 | AAA domain-containing protein; Belongs to the AAA ATPase family. (345 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1089 aa) |
| | PSME3 | Proteasome activator subunit 3. (247 aa) |
| | LIN54-2 | Uncharacterized protein. (59 aa) |
| | ENSAPLP00000023897 | Uncharacterized protein. (208 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (409 aa) |
| | ENSAPLP00000025322 | ANK_REP_REGION domain-containing protein. (136 aa) |
| | ENSAPLP00000025869 | ANK_REP_REGION domain-containing protein. (142 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (123 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1172 aa) |
| | ORC5 | Origin recognition complex subunit 5. (447 aa) |
| | ENSAPLP00000027614 | E2F_TDP domain-containing protein. (71 aa) |
| | WEE1 | WEE1 G2 checkpoint kinase. (283 aa) |
| | ENSAPLP00000028185 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (269 aa) |
| | ENSAPLP00000029327 | AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa) |
| | FNDC3B | Fibronectin type III domain containing 3B. (1169 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (362 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (608 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (948 aa) |
| | CCND3 | Cyclin_C domain-containing protein; Belongs to the cyclin family. (321 aa) |
| | POLE3 | CBFD_NFYB_HMF domain-containing protein. (143 aa) |
| | CDKN1A-2 | Uncharacterized protein. (182 aa) |
| | ENSAPLP00000031424 | Cyclin N-terminal domain-containing protein. (67 aa) |
| | ENSAPLP00000031212 | SH2 domain-containing protein. (71 aa) |
| | RPA3 | Replication protein A3. (132 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (685 aa) |
| | ENSAPLP00000030611 | Uncharacterized protein. (159 aa) |
| | ENSAPLP00000030500 | Protein kinase domain-containing protein. (80 aa) |
| | ENSAPLP00000030173 | Uncharacterized protein. (328 aa) |
| | ORC6 | Uncharacterized protein. (139 aa) |
| | ENSAPLP00000029691 | CYCLIN domain-containing protein; Belongs to the cyclin family. (189 aa) |
| | TFDP2 | Transcription factor Dp-2. (457 aa) |
