20 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	RSPO3	R-spondin 3. (319 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1149 aa)
	LGR4	Leucine rich repeat containing G protein-coupled receptor 4. (885 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (927 aa)
	LRP5	Uncharacterized protein. (471 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1603 aa)
	RNF43	RING-type domain-containing protein. (833 aa)
	LRTM1	Leucine rich repeats and transmembrane domains 1. (345 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (837 aa)
	RSPO1	R-spondin 1. (260 aa)
	ZNRF3	Zinc and ring finger 3. (862 aa)
	ENSAPLP00000023360	Uncharacterized protein. (359 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	FZD6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (890 aa)
	RSPO2	R-spondin 2. (247 aa)
	FZD8	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (682 aa)
	FZD4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
	FZD5	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (550 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000023360	ENSAPLP00000023897	ENSAPLP00000023360	ENSAPLP00000023897	Uncharacterized protein.	Uncharacterized protein.	0.527
ENSAPLP00000023360	LGR4	ENSAPLP00000023360	ENSAPLP00000002700	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 4.	0.749
ENSAPLP00000023360	LGR5	ENSAPLP00000023360	ENSAPLP00000015605	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 5.	0.655
ENSAPLP00000023360	LGR6	ENSAPLP00000023360	ENSAPLP00000006355	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 6.	0.557
ENSAPLP00000023360	RNF43	ENSAPLP00000023360	ENSAPLP00000012328	Uncharacterized protein.	RING-type domain-containing protein.	0.664
ENSAPLP00000023360	RPS27A	ENSAPLP00000023360	ENSAPLP00000004982	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.527
ENSAPLP00000023360	RSPO1	ENSAPLP00000023360	ENSAPLP00000018841	Uncharacterized protein.	R-spondin 1.	0.552
ENSAPLP00000023360	RSPO2	ENSAPLP00000023360	ENSAPLP00000029250	Uncharacterized protein.	R-spondin 2.	0.568
ENSAPLP00000023360	RSPO3	ENSAPLP00000023360	ENSAPLP00000001075	Uncharacterized protein.	R-spondin 3.	0.435
ENSAPLP00000023360	ZNRF3	ENSAPLP00000023360	ENSAPLP00000020653	Uncharacterized protein.	Zinc and ring finger 3.	0.524
ENSAPLP00000023897	ENSAPLP00000023360	ENSAPLP00000023897	ENSAPLP00000023360	Uncharacterized protein.	Uncharacterized protein.	0.527
ENSAPLP00000023897	FZD4	ENSAPLP00000023897	ENSAPLP00000031545	Uncharacterized protein.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.600
ENSAPLP00000023897	FZD5	ENSAPLP00000023897	ENSAPLP00000032188	Uncharacterized protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family.	0.485
ENSAPLP00000023897	FZD6	ENSAPLP00000023897	ENSAPLP00000028956	Uncharacterized protein.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.618
ENSAPLP00000023897	FZD8	ENSAPLP00000023897	ENSAPLP00000030062	Uncharacterized protein.	Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family.	0.485
ENSAPLP00000023897	LGR4	ENSAPLP00000023897	ENSAPLP00000002700	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 4.	0.521
ENSAPLP00000023897	LGR5	ENSAPLP00000023897	ENSAPLP00000015605	Uncharacterized protein.	Leucine rich repeat containing G protein-coupled receptor 5.	0.468
ENSAPLP00000023897	LRTM1	ENSAPLP00000023897	ENSAPLP00000012747	Uncharacterized protein.	Leucine rich repeats and transmembrane domains 1.	0.433
ENSAPLP00000023897	RNF43	ENSAPLP00000023897	ENSAPLP00000012328	Uncharacterized protein.	RING-type domain-containing protein.	0.641
ENSAPLP00000023897	RPS27A	ENSAPLP00000023897	ENSAPLP00000004982	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.997