STRINGSTRING
PDPK1 PDPK1 TP53RK TP53RK BRPF3 BRPF3 ING2 ING2 CDK3 CDK3 RMI1 RMI1 DYRK2 DYRK2 ZNF385C ZNF385C MAPKAP1 MAPKAP1 C28H17orf113 C28H17orf113 ZNF385B ZNF385B TP73 TP73 PIP4K2B PIP4K2B MAPK11 MAPK11 PIP4K2A PIP4K2A CCNA2 CCNA2 RPS27A RPS27A KAT6A KAT6A NBN NBN BLM BLM TBPL2 TBPL2 STK11 STK11 MEAF6 MEAF6 PPP1R13B PPP1R13B MTOR MTOR HIPK3 HIPK3 TBPL1 TBPL1 TP53INP1 TP53INP1 CDCA7 CDCA7 MEIOB MEIOB CCNA1 CCNA1 TAF10 TAF10 TAF3 TAF3 U3IR80_ANAPP U3IR80_ANAPP SUPT16H SUPT16H CDK1 CDK1 SMYD2 SMYD2 MDM2 MDM2 RBBP4 RBBP4 AKT3 AKT3 TP53BP2 TP53BP2 RBBP7 RBBP7 PIP4P2 PIP4P2 TBP TBP MDM4 MDM4 ATM ATM PRR5 PRR5 BRD7 BRD7 U3J214_ANAPP U3J214_ANAPP L3MBTL1 L3MBTL1 PIN1 PIN1 TDRD3 TDRD3 CHEK1 CHEK1 DYRK3 DYRK3 SSRP1 SSRP1 BRD1 BRD1 U3J9M0_ANAPP U3J9M0_ANAPP AKT1 AKT1 ENSAPLP00000016792 ENSAPLP00000016792 NOC2L NOC2L SGK1 SGK1 DYRK4 DYRK4 TAF2 TAF2 ENSAPLP00000018416 ENSAPLP00000018416 L3MBTL3 L3MBTL3 KXD1 KXD1 TAF9 TAF9 ENSAPLP00000021357 ENSAPLP00000021357 USP7 USP7 MRE11 MRE11 RECQL4 RECQL4 BRPF1 BRPF1 PRDM1 PRDM1 CSNK2A1 CSNK2A1 POU4F2 POU4F2 MLST8 MLST8 JMY JMY ENSAPLP00000023897 ENSAPLP00000023897 HIPK1 HIPK1 ENSAPLP00000024303 ENSAPLP00000024303 ENSAPLP00000024311 ENSAPLP00000024311 ENSAPLP00000024647 ENSAPLP00000024647 ENSAPLP00000024889 ENSAPLP00000024889 ENSAPLP00000024985 ENSAPLP00000024985 TXNDC11 TXNDC11 TP53INP2 TP53INP2 ENSAPLP00000026542 ENSAPLP00000026542 BANP BANP ENSAPLP00000026602 ENSAPLP00000026602 SETD9 SETD9 ENSAPLP00000027504 ENSAPLP00000027504 RICTOR RICTOR CCNG1 CCNG1 MAP2K6 MAP2K6 SUPT16H-2 SUPT16H-2 ENSAPLP00000029010 ENSAPLP00000029010 SLF1 SLF1 NUAK2 NUAK2 ENSAPLP00000030500 ENSAPLP00000030500 ENSAPLP00000030796 ENSAPLP00000030796 TAF5L TAF5L PHF20 PHF20 POU4F3 POU4F3 NUAK1 NUAK1 ING1 ING1 CSNK2A2 CSNK2A2 EXD2 EXD2 TP63 TP63 HIPK4 HIPK4 PWWP2A PWWP2A ENSAPLP00000032660 ENSAPLP00000032660
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
TP53RKTP53 regulating kinase. (276 aa)
BRPF3Bromodomain and PHD finger containing 3. (1182 aa)
ING2Inhibitor of growth protein. (246 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
RMI1RecQ mediated genome instability 1. (619 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (597 aa)
ZNF385CZinc finger protein 385C. (451 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
C28H17orf113Uncharacterized protein. (683 aa)
ZNF385BZinc finger protein 385B. (485 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (656 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (357 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (365 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (390 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2010 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (748 aa)
BLMBLM RecQ like helicase. (1302 aa)
TBPL2TATA-box binding protein like 2. (326 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (440 aa)
MEAF6MYST/Esa1 associated factor 6. (183 aa)
PPP1R13BProtein phosphatase 1 regulatory subunit 13B. (1186 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)
HIPK3Homeodomain interacting protein kinase 3. (1151 aa)
TBPL1TATA-box binding protein like 1. (183 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (237 aa)
CDCA7Cell division cycle associated 7. (239 aa)
MEIOBMeiosis specific with OB-fold. (476 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (339 aa)
TAF10TATA-box binding protein associated factor 10. (175 aa)
TAF3TATA-box binding protein associated factor 3. (926 aa)
U3IR80_ANAPPBromo domain-containing protein. (204 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (635 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
SMYD2SET and MYND domain containing 2. (547 aa)
MDM2Uncharacterized protein. (423 aa)
RBBP4RB binding protein 4, chromatin remodeling factor. (429 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
TP53BP2Tumor protein p53 binding protein 2. (1151 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (424 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
TBPTATA-box binding protein. (302 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (475 aa)
ATMNon-specific serine/threonine protein kinase. (2967 aa)
PRR5Proline rich 5. (413 aa)
BRD7Bromodomain containing 7. (711 aa)
U3J214_ANAPPInhibitor of growth protein. (227 aa)
L3MBTL1SAM domain-containing protein. (882 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (149 aa)
TDRD3Tudor domain containing 3. (741 aa)
CHEK1Checkpoint kinase 1. (435 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (575 aa)
SSRP1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (608 aa)
BRD1Bromodomain containing 1. (1167 aa)
U3J9M0_ANAPPUncharacterized protein. (824 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ENSAPLP00000016792Protein kinase domain-containing protein. (206 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (831 aa)
SGK1Non-specific serine/threonine protein kinase. (526 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (551 aa)
TAF2TATA-box binding protein associated factor 2. (1200 aa)
ENSAPLP00000018416POU domain protein. (376 aa)
L3MBTL3L3MBTL histone methyl-lysine binding protein 3. (909 aa)
KXD1KxDL motif containing 1. (353 aa)
TAF9TATA-box binding protein associated factor 9. (255 aa)
ENSAPLP00000021357Uncharacterized protein. (76 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1083 aa)
MRE11MRE11 homolog, double strand break repair nuclease. (230 aa)
RECQL4RecQ like helicase 4. (693 aa)
BRPF1Uncharacterized protein. (514 aa)
PRDM1PR/SET domain 1. (871 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa)
POU4F2POU domain protein. (411 aa)
MLST8MTOR associated protein, LST8 homolog. (355 aa)
JMYJunction mediating and regulatory protein, p53 cofactor. (895 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
HIPK1Homeodomain interacting protein kinase 1. (1608 aa)
ENSAPLP00000024303RING-type domain-containing protein. (385 aa)
ENSAPLP00000024311Uncharacterized protein. (145 aa)
ENSAPLP00000024647Uncharacterized protein. (520 aa)
ENSAPLP00000024889Uncharacterized protein. (222 aa)
ENSAPLP00000024985FOXP-CC domain-containing protein. (311 aa)
TXNDC11Thioredoxin domain-containing protein. (339 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (263 aa)
ENSAPLP00000026542SWIB domain-containing protein. (67 aa)
BANPBTG3 associated nuclear protein. (531 aa)
ENSAPLP00000026602Uncharacterized protein. (295 aa)
SETD9SET domain containing 9. (341 aa)
ENSAPLP00000027504SH3 domain-containing protein. (249 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1713 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (299 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (425 aa)
SUPT16H-2Uncharacterized protein. (87 aa)
ENSAPLP00000029010Uncharacterized protein. (366 aa)
SLF1SMC5-SMC6 complex localization factor 1. (940 aa)
NUAK2NUAK family kinase 2. (642 aa)
ENSAPLP00000030500Protein kinase domain-containing protein. (80 aa)
ENSAPLP00000030796Uncharacterized protein. (1090 aa)
TAF5LTATA-box binding protein associated factor 5 like. (589 aa)
PHF20PHD finger protein 20. (1059 aa)
POU4F3POU class 4 homeobox 3. (304 aa)
NUAK1NUAK family kinase 1. (687 aa)
ING1Inhibitor of growth protein. (387 aa)
CSNK2A2Casein kinase 2 alpha 2. (396 aa)
EXD2Exonuclease 3'-5' domain containing 2. (767 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
HIPK4Homeodomain interacting protein kinase 4. (561 aa)
PWWP2APWWP domain-containing protein. (208 aa)
ENSAPLP00000032660PWWP domain-containing protein. (141 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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