STRINGSTRING
ENSAPLP00000016895 ENSAPLP00000016895 FGF22 FGF22 U3J954_ANAPP U3J954_ANAPP KRAS KRAS PTPN11 PTPN11 BRAF BRAF FGFR1 FGFR1 CBL CBL FRS2 FRS2 PIK3CA PIK3CA HRAS HRAS SPRY2 SPRY2 FGF9 FGF9 SOS1 SOS1 FGF18 FGF18 FNDC3A FNDC3A NRAS NRAS SHC1 SHC1 U3IKP8_ANAPP U3IKP8_ANAPP FGF2 FGF2 FGF1 FGF1 RPS27A RPS27A FGF3 FGF3 FGF17 FGF17 FGF6 FGF6 FGF23 FGF23 FLRT2 FLRT2 GRB2 GRB2 SPRED1 SPRED1 SPRED2 SPRED2 FGF20 FGF20 ENSAPLP00000029488 ENSAPLP00000029488 FNDC3B FNDC3B GAB1 GAB1 FGF8 FGF8 FRS3 FRS3 MKNK1 MKNK1 ANOS1 ANOS1 FLRT3 FLRT3 ENSAPLP00000023897 ENSAPLP00000023897 MKNK2 MKNK2 FGF10 FGF10 CSDE1 CSDE1 FGFRL1 FGFRL1 PIK3R1 PIK3R1 FGF4 FGF4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSAPLP00000016895Uncharacterized protein. (72 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (367 aa)
U3J954_ANAPPTyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (660 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (755 aa)
FGFR1Fibroblast growth factor receptor. (813 aa)
CBLCbl proto-oncogene. (814 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
SPRY2Sprouty RTK signaling antagonist 2. (309 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1323 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (276 aa)
FNDC3AFibronectin type III domain containing 3A. (1175 aa)
NRASUncharacterized protein. (189 aa)
SHC1SHC adaptor protein 1. (616 aa)
U3IKP8_ANAPPUncharacterized protein. (1110 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (105 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (182 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (270 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (662 aa)
GRB2Growth factor receptor bound protein 2. (203 aa)
SPRED1Sprouty related EVH1 domain containing 1. (414 aa)
SPRED2Sprouty related EVH1 domain containing 2. (450 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (368 aa)
ENSAPLP00000029488Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (502 aa)
FNDC3BFibronectin type III domain containing 3B. (1169 aa)
GAB1GRB2 associated binding protein 1. (777 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (200 aa)
FRS3Fibroblast growth factor receptor substrate 3. (497 aa)
MKNK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (438 aa)
ANOS1Anosmin 1. (700 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (647 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
MKNK2MAPK interacting serine/threonine kinase 2. (286 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
CSDE1Cold shock domain containing E1. (796 aa)
FGFRL1Fibroblast growth factor receptor like 1. (526 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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