(74 nodes) Infectious disease network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KPNA4	Importin subunit alpha; Belongs to the importin alpha family. (521 aa)
	SIGMAR1	Sigma non-opioid intracellular receptor 1. (213 aa)
	KPNA3	Importin subunit alpha; Belongs to the importin alpha family. (523 aa)
	ZDHHC1	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (504 aa)
	EDEM2	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (463 aa)
	LARP1B	La ribonucleoprotein domain family member 1B. (751 aa)
	CHMP1B	Charged multivesicular body protein 1B. (196 aa)
	TGFBRAP1	CNH domain-containing protein. (522 aa)
	PSIP1	PC4 and SFRS1 interacting protein 1. (534 aa)
	ZDHHC3	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (299 aa)
	U3J0X8_ANAPP	Uncharacterized protein. (166 aa)
	IPO5	Importin 5. (1069 aa)
	CNBP	Uncharacterized protein. (170 aa)
	CORO2A	Coronin; Belongs to the WD repeat coronin family. (522 aa)
	SV2B	Synaptic vesicle glycoprotein 2B. (705 aa)
	ANTXR2	ANTXR cell adhesion molecule 2. (308 aa)
	IL10	Interleukin 10. (177 aa)
	VPS39	VPS39 subunit of HOPS complex. (841 aa)
	VPS18	VPS18 core subunit of CORVET and HOPS complexes. (1047 aa)
	ANTXR1	ANTXR cell adhesion molecule 1. (522 aa)
	MAN1B1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (646 aa)
	CEBPD	CCAAT enhancer binding protein delta. (353 aa)
	IL17D	Interleukin 17D. (207 aa)
	STT3B	STT3 oligosaccharyltransferase complex catalytic subunit B. (909 aa)
	RCAN2	Regulator of calcineurin 2. (533 aa)
	ENSAPLP00000019441	Poly [ADP-ribose] polymerase. (1828 aa)
	ENSAPLP00000019682	Uncharacterized protein. (861 aa)
	WIPF3	WAS/WASL interacting protein family member 3. (509 aa)
	DAD1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (257 aa)
	MOGS	Mannosyl-oligosaccharide glucosidase. (744 aa)
	CORO6	Coronin; Belongs to the WD repeat coronin family. (256 aa)
	VPS33B	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (1138 aa)
	GANAB	Glucosidase II alpha subunit; Belongs to the glycosyl hydrolase 31 family. (561 aa)
	ENSAPLP00000023451	Vps39_2 domain-containing protein. (300 aa)
	RBM43	RRM domain-containing protein. (526 aa)
	RCAN3	RCAN family member 3. (283 aa)
	GRSF1	G-rich RNA sequence binding factor 1. (413 aa)
	ENSAPLP00000024387	Uncharacterized protein. (341 aa)
	ENSAPLP00000024220	Ig-like domain-containing protein. (305 aa)
	RCAN1	Regulator of calcineurin 1. (274 aa)
	ANTXRL	ANTXR like. (557 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (499 aa)
	IL-17	Uncharacterized protein. (191 aa)
	ACP1	Acid phosphatase 1. (149 aa)
	CORO2B	Coronin; Belongs to the WD repeat coronin family. (173 aa)
	ENSAPLP00000029002	Uncharacterized protein. (154 aa)
	CORO1C	Coronin 1C. (179 aa)
	SRPK2	SRSF protein kinase 2. (738 aa)
	PACS2	Phosphofurin acidic cluster sorting protein 2. (928 aa)
	ENSAPLP00000030931	Uncharacterized protein. (627 aa)
	ENSAPLP00000030943	Poly [ADP-ribose] polymerase. (1906 aa)
	ENSAPLP00000031423	Uncharacterized protein. (703 aa)
	G3BP1	G3BP stress granule assembly factor 1. (486 aa)
	U3I0K3_ANAPP	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (102 aa)
	STT3A	STT3 oligosaccharyltransferase complex catalytic subunit A. (550 aa)
	MPDZ	Multiple PDZ domain crumbs cell polarity complex component. (2051 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (722 aa)
	ENSAPLP00000024730	Uncharacterized protein. (65 aa)
	PATJ	Uncharacterized protein. (640 aa)
	PDZD3	PDZ domain containing 3. (467 aa)
	SRPK1	SRSF protein kinase 1. (664 aa)
	CRBN	Cereblon. (446 aa)
	RANBP1	RAN binding protein 1. (209 aa)
	SV2A	Synaptic vesicle glycoprotein 2A. (404 aa)
	RPN1	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (592 aa)
	SV2C	Synaptic vesicle glycoprotein 2C. (727 aa)
	U3I9Z4_ANAPP	Ig-like domain-containing protein. (379 aa)
	RPN2	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (558 aa)
	CHMP1A	Charged multivesicular body protein 1A. (195 aa)
	IL18	Interleukin-18. (197 aa)
	VPS33A	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (612 aa)
	LARP1	La ribonucleoprotein domain family member 1. (1084 aa)
	PRKX	Uncharacterized protein. (345 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (929 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACP1	RCAN1	ENSAPLP00000027151	ENSAPLP00000025705	Acid phosphatase 1.	Regulator of calcineurin 1.	0.546
ANTXRL	CHMP1B	ENSAPLP00000026534	ENSAPLP00000010429	ANTXR like.	Charged multivesicular body protein 1B.	0.614
ANTXRL	CRBN	ENSAPLP00000026534	ENSAPLP00000003416	ANTXR like.	Cereblon.	0.501
CHMP1B	ANTXRL	ENSAPLP00000010429	ENSAPLP00000026534	Charged multivesicular body protein 1B.	ANTXR like.	0.614
CORO1C	CORO2B	ENSAPLP00000029629	ENSAPLP00000028628	Coronin 1C.	Coronin; Belongs to the WD repeat coronin family.	0.870
CORO1C	CORO6	ENSAPLP00000029629	ENSAPLP00000021481	Coronin 1C.	Coronin; Belongs to the WD repeat coronin family.	0.911
CORO2B	CORO1C	ENSAPLP00000028628	ENSAPLP00000029629	Coronin; Belongs to the WD repeat coronin family.	Coronin 1C.	0.870
CORO2B	ENSAPLP00000024387	ENSAPLP00000028628	ENSAPLP00000024387	Coronin; Belongs to the WD repeat coronin family.	Uncharacterized protein.	0.900
CORO6	CORO1C	ENSAPLP00000021481	ENSAPLP00000029629	Coronin; Belongs to the WD repeat coronin family.	Coronin 1C.	0.911
CORO6	ENSAPLP00000024387	ENSAPLP00000021481	ENSAPLP00000024387	Coronin; Belongs to the WD repeat coronin family.	Uncharacterized protein.	0.871
CRBN	ANTXRL	ENSAPLP00000003416	ENSAPLP00000026534	Cereblon.	ANTXR like.	0.501
DAD1	RPN1	ENSAPLP00000020877	ENSAPLP00000003935	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.994
DAD1	RPN2	ENSAPLP00000020877	ENSAPLP00000004514	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.995
DAD1	STT3A	ENSAPLP00000020877	ENSAPLP00000032108	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	STT3 oligosaccharyltransferase complex catalytic subunit A.	0.989
DAD1	STT3B	ENSAPLP00000020877	ENSAPLP00000017553	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	STT3 oligosaccharyltransferase complex catalytic subunit B.	0.983
DAD1	ZDHHC3	ENSAPLP00000020877	ENSAPLP00000012220	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...]	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.	0.521
EDEM2	RPN1	ENSAPLP00000009443	ENSAPLP00000003935	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]	0.436
ENSAPLP00000023451	TGFBRAP1	ENSAPLP00000023451	ENSAPLP00000011503	Vps39_2 domain-containing protein.	CNH domain-containing protein.	0.900
ENSAPLP00000023451	VPS11	ENSAPLP00000023451	ENSAPLP00000007398	Vps39_2 domain-containing protein.	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family.	0.923
ENSAPLP00000023451	VPS18	ENSAPLP00000023451	ENSAPLP00000015915	Vps39_2 domain-containing protein.	VPS18 core subunit of CORVET and HOPS complexes.	0.921