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| | TADA2B | Transcriptional adapter. (420 aa) |
| | RNF146 | Ring finger protein 146. (352 aa) |
| | ZFYVE19 | Zinc finger FYVE-type containing 19. (420 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (369 aa) |
| | U3I0H3_ANAPP | Uncharacterized protein. (55 aa) |
| | ADRB2 | Adrenoceptor beta 2. (402 aa) |
| | NPEPL1 | Aminopeptidase like 1. (523 aa) |
| | USP8 | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1149 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase. (961 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1143 aa) |
| | NRDC | Uncharacterized protein; Belongs to the peptidase M16 family. (1145 aa) |
| | USP46 | Ubiquitin carboxyl-terminal hydrolase. (381 aa) |
| | USP3 | Ubiquitin carboxyl-terminal hydrolase. (430 aa) |
| | ATXN7 | SCA7 domain-containing protein. (874 aa) |
| | USP5 | Ubiquitin carboxyl-terminal hydrolase. (822 aa) |
| | USP48 | Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (954 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (551 aa) |
| | KLHL18 | Kelch like family member 18. (581 aa) |
| | BECN1 | Uncharacterized protein. (452 aa) |
| | USP44 | Ubiquitinyl hydrolase 1. (494 aa) |
| | USP16 | Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (819 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | USP34 | Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3522 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (390 aa) |
| | USP12 | Ubiquitin specific peptidase 12; Belongs to the peptidase C19 family. (319 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | BIRC2 | Uncharacterized protein. (611 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (782 aa) |
| | USP37 | USP domain-containing protein; Belongs to the peptidase C19 family. (276 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | AXIN1 | Axin 1. (841 aa) |
| | VDAC3 | Voltage dependent anion channel 3. (296 aa) |
| | U3IFZ0_ANAPP | DNA_pol_B_thumb domain-containing protein. (54 aa) |
| | AR | Androgen receptor. (385 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (426 aa) |
| | WDR76 | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (596 aa) |
| | LAP3 | Leucine aminopeptidase 3. (519 aa) |
| | USP18 | USP domain-containing protein; Belongs to the peptidase C19 family. (414 aa) |
| | RNF123 | Ring finger protein 123. (1212 aa) |
| | USP19 | Ubiquitin specific peptidase 19. (1415 aa) |
| | USP32 | Uncharacterized protein; Belongs to the peptidase C19 family. (1593 aa) |
| | PSMA1 | Proteasome subunit alpha type. (259 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (515 aa) |
| | U3IL93_ANAPP | USP domain-containing protein; Belongs to the peptidase C19 family. (369 aa) |
| | MAP3K20-2 | SAM domain-containing protein. (549 aa) |
| | KLHL17 | Kelch like family member 17. (590 aa) |
| | PSME4 | BLM10_mid domain-containing protein. (581 aa) |
| | USP20 | Ubiquitin carboxyl-terminal hydrolase. (889 aa) |
| | U3IMS8_ANAPP | Uncharacterized protein; Belongs to the peptidase C19 family. (807 aa) |
| | U3IPC0_ANAPP | Uncharacterized protein; Belongs to the peptidase M16 family. (1004 aa) |
| | RNF13 | Ring finger protein 13. (381 aa) |
| | H2BE1 | Histone H2B; Belongs to the histone H2B family. (162 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (339 aa) |
| | SMURF2 | SMAD specific E3 ubiquitin protein ligase 2. (682 aa) |
| | TAF10 | TATA-box binding protein associated factor 10. (175 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | U3IRF0_ANAPP | Uncharacterized protein. (252 aa) |
| | CLSPN | Claspin. (1374 aa) |
| | CDC20 | Cell division cycle 20. (505 aa) |
| | IFIH1 | Interferon induced with helicase C domain 1. (1003 aa) |
| | AXIN2 | DIX domain-containing protein. (274 aa) |
| | TNKS2 | Poly [ADP-ribose] polymerase. (1109 aa) |
| | MDM2 | Uncharacterized protein. (423 aa) |
| | CFTR | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1548 aa) |
| | USP13 | Ubiquitin carboxyl-terminal hydrolase. (856 aa) |
| | ADRM1 | Adhesion regulating molecule 1. (405 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | VDAC2 | Voltage dependent anion channel 2. (296 aa) |
| | WDR48 | WD repeat domain 48. (678 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate. (726 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (475 aa) |
| | CCP110 | Centriolar coiled-coil protein 110. (994 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | WDR20 | WD repeat domain 20. (592 aa) |
| | U3J1W2_ANAPP | Uncharacterized protein. (160 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (945 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (452 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (418 aa) |
| | RNF128 | Ring finger protein 128. (406 aa) |
| | SNX12 | Sorting nexin 12. (254 aa) |
| | FOXO4 | Forkhead box O4. (455 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (191 aa) |
| | USP4 | Ubiquitin carboxyl-terminal hydrolase. (956 aa) |
| | USP30 | Ubiquitin carboxyl-terminal hydrolase. (481 aa) |
| | DDX58 | DExD/H-box helicase 58. (880 aa) |
| | VDAC1 | Voltage dependent anion channel 1. (283 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (690 aa) |
| | USP28 | Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1129 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | UBLCP1 | Ubiquitin like domain containing CTD phosphatase 1. (340 aa) |
| | IDE | Insulin degrading enzyme; Belongs to the peptidase M16 family. (1049 aa) |
| | PSMC1 | Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (440 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (531 aa) |
| | UBFD1 | Ubiquitin family domain containing 1. (317 aa) |
| | ARRB1 | Arrestin beta 1. (217 aa) |
| | ENSAPLP00000017335 | UBP-type domain-containing protein. (61 aa) |
| | SKP2 | S-phase kinase associated protein 2. (671 aa) |
| | ENSAPLP00000017850 | Uncharacterized protein. (188 aa) |
| | USP25 | Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1014 aa) |
| | KXD1 | KxDL motif containing 1. (353 aa) |
| | ENSAPLP00000018852 | RING-type domain-containing protein. (93 aa) |
| | TOMM20 | Translocase of outer mitochondrial membrane 20. (209 aa) |
| | UFD1 | Ubiquitin recognition factor in ER associated degradation 1. (318 aa) |
| | USP21 | Ubiquitin specific peptidase 21. (329 aa) |
| | ENSAPLP00000020785 | RGS domain-containing protein. (143 aa) |
| | USP7 | Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1083 aa) |
| | ENSAPLP00000021459 | Uncharacterized protein. (188 aa) |
| | ENSAPLP00000022298 | USP domain-containing protein; Belongs to the peptidase C19 family. (417 aa) |
| | TADA3 | Transcriptional adaptor 3. (434 aa) |
| | ENSAPLP00000023122 | AAA domain-containing protein; Belongs to the AAA ATPase family. (345 aa) |
| | USP49 | Ubiquitin carboxyl-terminal hydrolase. (726 aa) |
| | USP10 | Ubiquitin carboxyl-terminal hydrolase. (799 aa) |
| | ENSAPLP00000023658 | RING-type domain-containing protein. (409 aa) |
| | ENSAPLP00000023897 | Uncharacterized protein. (208 aa) |
| | ATXN7L2 | Ataxin 7 like 2. (798 aa) |
| | ARR3 | Arrestin 3. (279 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7. (644 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa) |
| | USP33 | Ubiquitin carboxyl-terminal hydrolase. (931 aa) |
| | ENSAPLP00000024926 | HHH_8 domain-containing protein. (91 aa) |
| | TOMM70 | TPR_REGION domain-containing protein. (95 aa) |
| | USP24 | Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2622 aa) |
| | MUL1 | Mitochondrial E3 ubiquitin protein ligase 1. (175 aa) |
| | ENSAPLP00000026079 | DUF3437 domain-containing protein. (220 aa) |
| | ENSAPLP00000026294 | HHH_8 domain-containing protein. (101 aa) |
| | ENSAPLP00000026403 | PA domain-containing protein. (178 aa) |
| | ENSAPLP00000026542 | SWIB domain-containing protein. (67 aa) |
| | USP42 | USP domain-containing protein; Belongs to the peptidase C19 family. (249 aa) |
| | ATXN7L1 | Ataxin 7 like 1. (851 aa) |
| | ENSAPLP00000026997 | Uncharacterized protein; Belongs to the histone H2B family. (145 aa) |
| | USP22 | Ubiquitinyl hydrolase 1. (444 aa) |
| | CYLD | CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (970 aa) |
| | STAM2 | Signal transducing adaptor molecule 2. (537 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa) |
| | RCE1 | Ras converting CAAX endopeptidase 1. (228 aa) |
| | ENSAPLP00000028423 | Uncharacterized protein; Belongs to the histone H2B family. (122 aa) |
| | OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1. (129 aa) |
| | ENSAPLP00000029327 | AAA domain-containing protein; Belongs to the AAA ATPase family. (393 aa) |
| | MTFP1 | Mitochondrial fission process 1. (161 aa) |
| | MAT2B | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (339 aa) |
| | ENSAPLP00000029576 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | ENSAPLP00000029747 | RING-type domain-containing protein. (123 aa) |
| | ENSAPLP00000029886 | USP domain-containing protein; Belongs to the peptidase C19 family. (284 aa) |
| | USP2 | Ubiquitin specific peptidase 2; Belongs to the peptidase C19 family. (450 aa) |
| | ENSAPLP00000031586 | Arrestin_N domain-containing protein. (295 aa) |
| | ENSAPLP00000031650 | Uncharacterized protein. (142 aa) |
| | ENSAPLP00000031941 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | CDC20B | Cell division cycle 20B. (405 aa) |
| | SIAH2 | E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (298 aa) |
