27 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	MDM4	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (475 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	ATM	Non-specific serine/threonine protein kinase. (2967 aa)
	PRR5	Proline rich 5. (413 aa)
	ENSAPLP00000030500	Protein kinase domain-containing protein. (80 aa)
	CCNG1	Cyclin G1; Belongs to the cyclin family. (299 aa)
	RICTOR	RPTOR independent companion of MTOR complex 2. (1713 aa)
	ENSAPLP00000026602	Uncharacterized protein. (295 aa)
	PDPK1	3-phosphoinositide dependent protein kinase 1. (556 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSAPLP00000016792	Protein kinase domain-containing protein. (206 aa)
	SGK1	Non-specific serine/threonine protein kinase. (526 aa)
	KXD1	KxDL motif containing 1. (353 aa)
	USP7	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1083 aa)
	MLST8	MTOR associated protein, LST8 homolog. (355 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	ENSAPLP00000024303	RING-type domain-containing protein. (385 aa)
	TXNDC11	Thioredoxin domain-containing protein. (339 aa)
	ENSAPLP00000026542	SWIB domain-containing protein. (67 aa)
	CCNA2	Cyclin A2; Belongs to the cyclin family. (390 aa)
	MAPKAP1	MAPK associated protein 1. (522 aa)
	CDK3	Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
	MDM2	Uncharacterized protein. (423 aa)
	CCNA1	Cyclin A1; Belongs to the cyclin family. (339 aa)
	MTOR	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2538 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT3	ENSAPLP00000016229	ENSAPLP00000011266	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	ENSAPLP00000026542	ENSAPLP00000016229	ENSAPLP00000026542	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	SWIB domain-containing protein.	0.602
AKT1	MAPKAP1	ENSAPLP00000016229	ENSAPLP00000002331	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK associated protein 1.	0.621
AKT1	MDM2	ENSAPLP00000016229	ENSAPLP00000010914	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.970
AKT1	MDM4	ENSAPLP00000016229	ENSAPLP00000012492	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.506
AKT1	MLST8	ENSAPLP00000016229	ENSAPLP00000023743	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MTOR associated protein, LST8 homolog.	0.533
AKT1	MTOR	ENSAPLP00000016229	ENSAPLP00000007032	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.967
AKT1	PDPK1	ENSAPLP00000016229	ENSAPLP00000015587	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.995
AKT1	RICTOR	ENSAPLP00000016229	ENSAPLP00000027785	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RPTOR independent companion of MTOR complex 2.	0.720
AKT1	SGK1	ENSAPLP00000016229	ENSAPLP00000017310	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.535
AKT3	AKT1	ENSAPLP00000011266	ENSAPLP00000016229	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT3	ENSAPLP00000026542	ENSAPLP00000011266	ENSAPLP00000026542	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	SWIB domain-containing protein.	0.602
AKT3	MAPKAP1	ENSAPLP00000011266	ENSAPLP00000002331	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MAPK associated protein 1.	0.621
AKT3	MDM2	ENSAPLP00000011266	ENSAPLP00000010914	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.963
AKT3	MDM4	ENSAPLP00000011266	ENSAPLP00000012492	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.506
AKT3	MLST8	ENSAPLP00000011266	ENSAPLP00000023743	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	MTOR associated protein, LST8 homolog.	0.533
AKT3	MTOR	ENSAPLP00000011266	ENSAPLP00000007032	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.967
AKT3	PDPK1	ENSAPLP00000011266	ENSAPLP00000015587	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	3-phosphoinositide dependent protein kinase 1.	0.982
AKT3	RICTOR	ENSAPLP00000011266	ENSAPLP00000027785	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	RPTOR independent companion of MTOR complex 2.	0.720
AKT3	SGK1	ENSAPLP00000011266	ENSAPLP00000017310	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.533