STRINGSTRING
ORC3 ORC3 POLE3 POLE3 CDC23 CDC23 ENSAPLP00000031284 ENSAPLP00000031284 ENSAPLP00000030611 ENSAPLP00000030611 ORC6 ORC6 ANAPC10 ANAPC10 PCNA PCNA ORC5 ORC5 UBE2C UBE2C MCM9 MCM9 FZR1 FZR1 GINS2 GINS2 ENSAPLP00000026079 ENSAPLP00000026079 POLE4 POLE4 CDC26 CDC26 RCBTB1 RCBTB1 CDC27 CDC27 ENSAPLP00000023897 ENSAPLP00000023897 GINS3 GINS3 ATAD5 ATAD5 TM7SF3 TM7SF3 ENSAPLP00000021459 ENSAPLP00000021459 POLD2 POLD2 CUL1 CUL1 GINS4 GINS4 PRIM1 PRIM1 RCBTB2 RCBTB2 KXD1 KXD1 SKP2 SKP2 ANAPC15 ANAPC15 ANAPC16 ANAPC16 PSMC1 PSMC1 MCM6 MCM6 SKP1 SKP1 TM4SF19 TM4SF19 PSMD10 PSMD10 PSMD1 PSMD1 CCNE1 CCNE1 LIG1 LIG1 MCM3 MCM3 GMNN GMNN PSMA7 PSMA7 ANAPC1 ANAPC1 CDC16 CDC16 ORC4 ORC4 RFC1 RFC1 RBX1 RBX1 RFC3 RFC3 POLE POLE CCNA1 CCNA1 RFC2 RFC2 POLA1 POLA1 PSME4 PSME4 MEIOB MEIOB MCM5 MCM5 PSMA1 PSMA1 CCNE2 CCNE2 POLE2 POLE2 RFC4 RFC4 MCM8 MCM8 CDT1 CDT1 U3IG37_ANAPP U3IG37_ANAPP RPS27A RPS27A POLD3 POLD3 ORC1 ORC1 CCNA2 CCNA2 MCM2 MCM2 ANAPC7 ANAPC7 PRIM2 PRIM2 ANAPC5 ANAPC5 MCM4 MCM4 RFC5 RFC5 ANAPC2 ANAPC2 FAM89A FAM89A CDK3 CDK3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ORC3Origin recognition complex subunit 3. (682 aa)
POLE3CBFD_NFYB_HMF domain-containing protein. (143 aa)
CDC23Cell division cycle 23. (722 aa)
ENSAPLP00000031284ANAPC4_WD40 domain-containing protein. (190 aa)
ENSAPLP00000030611Uncharacterized protein. (159 aa)
ORC6Uncharacterized protein. (139 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
ORC5Origin recognition complex subunit 5. (447 aa)
UBE2CUbiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (87 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1172 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
ENSAPLP00000026079DUF3437 domain-containing protein. (220 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (123 aa)
CDC26Cell division cycle 26. (83 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (713 aa)
CDC27Cell division cycle 27. (834 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
GINS3GINS complex subunit 3. (214 aa)
ATAD5Uncharacterized protein. (587 aa)
TM7SF3Transmembrane 7 superfamily member 3. (580 aa)
ENSAPLP00000021459Uncharacterized protein. (188 aa)
POLD2DNA polymerase delta 2, accessory subunit. (554 aa)
CUL1Cullin 1; Belongs to the cullin family. (768 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (222 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (463 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
KXD1KxDL motif containing 1. (353 aa)
SKP2S-phase kinase associated protein 2. (671 aa)
ANAPC15Anaphase promoting complex subunit 15. (89 aa)
ANAPC16Uncharacterized protein. (468 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
MCM6DNA helicase; Belongs to the MCM family. (830 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
TM4SF19Uncharacterized protein. (258 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (191 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (945 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (384 aa)
LIG1DNA ligase. (657 aa)
MCM3DNA helicase; Belongs to the MCM family. (810 aa)
GMNNUncharacterized protein. (407 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ANAPC1Anaphase promoting complex subunit 1. (1910 aa)
CDC16Cell division cycle 16. (623 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
RFC1Replication factor C subunit 1. (1145 aa)
RBX1Ring-box 1. (108 aa)
RFC3Replication factor C subunit 3. (356 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2285 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (339 aa)
RFC2Replication factor C subunit 2. (352 aa)
POLA1DNA polymerase. (1490 aa)
PSME4BLM10_mid domain-containing protein. (581 aa)
MEIOBMeiosis specific with OB-fold. (476 aa)
MCM5DNA helicase; Belongs to the MCM family. (828 aa)
PSMA1Proteasome subunit alpha type. (259 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (405 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
RFC4Replication factor C subunit 4. (362 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (833 aa)
CDT1Chromatin licensing and DNA replication factor 1. (353 aa)
U3IG37_ANAPPATPase_AAA_core domain-containing protein. (1104 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
POLD3Uncharacterized protein. (464 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (390 aa)
MCM2DNA helicase; Belongs to the MCM family. (889 aa)
ANAPC7Anaphase promoting complex subunit 7. (513 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (508 aa)
ANAPC5Anaphase promoting complex subunit 5. (744 aa)
MCM4DNA helicase; Belongs to the MCM family. (861 aa)
RFC5Replication factor C subunit 5. (211 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (811 aa)
FAM89AUncharacterized protein. (83 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (305 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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