17 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	PSMA1	Proteasome subunit alpha type. (259 aa)
	PSME4	BLM10_mid domain-containing protein. (581 aa)
	MDM2	Uncharacterized protein. (423 aa)
	MDM4	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (475 aa)
	ATM	Non-specific serine/threonine protein kinase. (2967 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (945 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (191 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
	KXD1	KxDL motif containing 1. (353 aa)
	COP1	COP1 E3 ubiquitin ligase. (642 aa)
	ENSAPLP00000021459	Uncharacterized protein. (188 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	ENSAPLP00000026079	DUF3437 domain-containing protein. (220 aa)
	ENSAPLP00000026542	SWIB domain-containing protein. (67 aa)
	PWWP2A	PWWP domain-containing protein. (208 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	COP1	ENSAPLP00000012640	ENSAPLP00000020292	Non-specific serine/threonine protein kinase.	COP1 E3 ubiquitin ligase.	0.641
ATM	ENSAPLP00000023897	ENSAPLP00000012640	ENSAPLP00000023897	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.626
ATM	ENSAPLP00000026542	ENSAPLP00000012640	ENSAPLP00000026542	Non-specific serine/threonine protein kinase.	SWIB domain-containing protein.	0.805
ATM	MDM2	ENSAPLP00000012640	ENSAPLP00000010914	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.875
ATM	MDM4	ENSAPLP00000012640	ENSAPLP00000012492	Non-specific serine/threonine protein kinase.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.785
ATM	RPS27A	ENSAPLP00000012640	ENSAPLP00000004982	Non-specific serine/threonine protein kinase.	Ubiquitin-like domain-containing protein.	0.592
COP1	ATM	ENSAPLP00000020292	ENSAPLP00000012640	COP1 E3 ubiquitin ligase.	Non-specific serine/threonine protein kinase.	0.641
COP1	ENSAPLP00000023897	ENSAPLP00000020292	ENSAPLP00000023897	COP1 E3 ubiquitin ligase.	Uncharacterized protein.	0.617
COP1	PSMC1	ENSAPLP00000020292	ENSAPLP00000016454	COP1 E3 ubiquitin ligase.	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.	0.416
COP1	PSMD10	ENSAPLP00000020292	ENSAPLP00000014554	COP1 E3 ubiquitin ligase.	Proteasome 26S subunit, non-ATPase 10.	0.415
COP1	RPS27A	ENSAPLP00000020292	ENSAPLP00000004982	COP1 E3 ubiquitin ligase.	Ubiquitin-like domain-containing protein.	0.627
ENSAPLP00000021459	ENSAPLP00000023897	ENSAPLP00000021459	ENSAPLP00000023897	Uncharacterized protein.	Uncharacterized protein.	0.926
ENSAPLP00000021459	ENSAPLP00000026079	ENSAPLP00000021459	ENSAPLP00000026079	Uncharacterized protein.	DUF3437 domain-containing protein.	0.877
ENSAPLP00000021459	PSMA1	ENSAPLP00000021459	ENSAPLP00000007531	Uncharacterized protein.	Proteasome subunit alpha type.	0.996
ENSAPLP00000021459	PSMA7	ENSAPLP00000021459	ENSAPLP00000012806	Uncharacterized protein.	Proteasome subunit alpha type.	0.997
ENSAPLP00000021459	PSMC1	ENSAPLP00000021459	ENSAPLP00000016454	Uncharacterized protein.	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.	0.994
ENSAPLP00000021459	PSMD1	ENSAPLP00000021459	ENSAPLP00000013650	Uncharacterized protein.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.971
ENSAPLP00000021459	PSME4	ENSAPLP00000021459	ENSAPLP00000008197	Uncharacterized protein.	BLM10_mid domain-containing protein.	0.877
ENSAPLP00000021459	RPS27A	ENSAPLP00000021459	ENSAPLP00000004982	Uncharacterized protein.	Ubiquitin-like domain-containing protein.	0.918
ENSAPLP00000023897	ATM	ENSAPLP00000023897	ENSAPLP00000012640	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.626