(133 nodes) Eukaryotic Translation Initiation network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EIF2B4	Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (520 aa)
	RPL23A	Uncharacterized protein; Belongs to the universal ribosomal protein uL23 family. (70 aa)
	RPS28	Ribosomal protein S28. (69 aa)
	EIF4E1B	Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (117 aa)
	RPL38	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (112 aa)
	RPL29	60S ribosomal protein L29; Belongs to the eukaryotic ribosomal protein eL29 family. (140 aa)
	ENSAPLP00000024949	Uncharacterized protein. (222 aa)
	EIF3G	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (321 aa)
	ENSAPLP00000025047	Uncharacterized protein. (66 aa)
	EIF4EBP3	Eukaryotic translation initiation factor 4E binding protein 3. (102 aa)
	RPL37	Ribosomal protein L37; Binds to the 23S rRNA. (97 aa)
	EIF5	Eukaryotic translation initiation factor 5. (430 aa)
	EIF4EBP2	Eukaryotic translation initiation factor 4E binding protein 2. (116 aa)
	ENSAPLP00000026123	Uncharacterized protein. (192 aa)
	ENSAPLP00000026595	Ribosomal_L7Ae domain-containing protein. (139 aa)
	RPL10A	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. (119 aa)
	EIF2S1	Eukaryotic translation initiation factor 2 subunit alpha. (167 aa)
	RPS25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (93 aa)
	RPS11	Ribosomal protein S11. (221 aa)
	EIF3H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (418 aa)
	RPS5	Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (276 aa)
	RPL22	Uncharacterized protein. (128 aa)
	ENSAPLP00000029082	Uncharacterized protein. (143 aa)
	ENSAPLP00000029212	Uncharacterized protein. (130 aa)
	ENSAPLP00000029385	Uncharacterized protein. (115 aa)
	ENSAPLP00000029580	Uncharacterized protein. (99 aa)
	ENSAPLP00000029620	NTP_transferase domain-containing protein. (111 aa)
	ENSAPLP00000029709	Uncharacterized protein. (55 aa)
	RSAD1	Radical S-adenosyl methionine domain containing 1. (750 aa)
	RPS10	Ribosomal protein S10. (196 aa)
	EIF3B	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (849 aa)
	RPL39	Ribosomal protein L39. (51 aa)
	RPS15	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (158 aa)
	RPS23	Ribosomal protein S23. (211 aa)
	RPL11	Ribosomal protein L11. (123 aa)
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (297 aa)
	ENSAPLP00000032726	LIM zinc-binding domain-containing protein. (546 aa)
	RPL36	60S ribosomal protein L36; Belongs to the eukaryotic ribosomal protein eL36 family. (185 aa)
	RPS21	Ribosomal protein S21. (84 aa)
	RPS7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	EIF3D	Eukaryotic translation initiation factor 3 subunit D. (396 aa)
	RPS3A	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (264 aa)
	RNPEPL1	Arginyl aminopeptidase like 1. (781 aa)
	RPS27L	40S ribosomal protein S27. (84 aa)
	RPL24	Ribosomal protein L24. (157 aa)
	RPS17	Ribosomal protein S17. (135 aa)
	RPL14	Ribosomal protein L14. (121 aa)
	RPL27A	Ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family. (148 aa)
	RPL27	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (136 aa)
	RPL32	Uncharacterized protein. (135 aa)
	RPL35	Ribosomal protein L35. (105 aa)
	RSRC1	Arginine and serine rich coiled-coil 1. (306 aa)
	RPL7A	Ribosomal_L7Ae domain-containing protein. (136 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	RPL12	Ribosomal protein L12; Belongs to the universal ribosomal protein uL11 family. (169 aa)
	EIF2B5	Eukaryotic translation initiation factor 2B subunit epsilon. (708 aa)
	RPL15	Ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. (204 aa)
	RPL21	Uncharacterized protein. (252 aa)
	U3IDF0_ANAPP	Q_MOTIF domain-containing protein. (139 aa)
	EIF3E	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (445 aa)
	RPL7	Ribosomal protein L7. (274 aa)
	EIF3M	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (374 aa)
	EIF3A	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1194 aa)
	EIF4A2	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (390 aa)
	RPS4X	Ribosomal protein S4 X-linked. (324 aa)
	RPS20	Ribosomal_S10 domain-containing protein. (64 aa)
	RPL34	Ribosomal protein L34. (117 aa)
	RPL18A	Ribosomal protein L18a. (113 aa)
	U3ILL9_ANAPP	Uncharacterized protein; Belongs to the universal ribosomal protein uL22 family. (181 aa)
	EIF3J	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (293 aa)
	RPS2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (286 aa)
	RPS12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	RPS8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (213 aa)
	EIF4H	Eukaryotic translation initiation factor 4H. (251 aa)
	RPL37A	Uncharacterized protein. (74 aa)
	EIF2B2	Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (348 aa)
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (194 aa)
	RPL23	Ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. (161 aa)
	RPL36AL	Ribosomal protein L36a like; Belongs to the eukaryotic ribosomal protein eL42 family. (113 aa)
	EIF2B3	Uncharacterized protein. (373 aa)
	EIF2S3	Tr-type G domain-containing protein. (472 aa)
	RPS15A	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	ARL6IP1	Uncharacterized protein. (203 aa)
	RPL9	Ribosomal protein L9. (192 aa)
	RPS13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (151 aa)
	RPLP0	60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (318 aa)
	RPLP2	Ribosomal protein lateral stalk subunit P2; Belongs to the eukaryotic ribosomal protein P1/P2 family. (100 aa)
	EIF2S2	Eukaryotic translation initiation factor 2 subunit beta. (329 aa)
	EIF3I	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (329 aa)
	RPL7L1	Ribosomal protein L7 like 1. (247 aa)
	U3J237_ANAPP	Uncharacterized protein. (619 aa)
	RPS14	Ribosomal protein S14. (154 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	RPL8	Ribosomal protein L8. (257 aa)
	RPL3	Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. (409 aa)
	EIF2B1	Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (330 aa)
	RPL26	Ribosomal protein L26. (240 aa)
	RPL6	60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (276 aa)
	EIF4EBP1	Eukaryotic translation initiation factor 4E binding protein 1. (100 aa)
	RPL4	Ribosomal protein L4. (391 aa)
	RPS16	Ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (146 aa)
	EIF4E	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (230 aa)
	RPL5	Ribosomal_L18_c domain-containing protein. (246 aa)
	RPL31	Uncharacterized protein. (125 aa)
	ENSAPLP00000016573	RRM domain-containing protein. (278 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1408 aa)
	ENSAPLP00000016641	SelP_N domain-containing protein. (225 aa)
	ENSAPLP00000016704	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein eL38 family. (202 aa)
	EIF3F	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (481 aa)
	ENSAPLP00000016913	Uncharacterized protein. (110 aa)
	RPL35A	Uncharacterized protein. (133 aa)
	ENSAPLP00000017702	NTP_transferase domain-containing protein. (111 aa)
	RPS6	Uncharacterized protein. (492 aa)
	KXD1	KxDL motif containing 1. (353 aa)
	ENSAPLP00000019101	Uncharacterized protein. (101 aa)
	RPS19	Uncharacterized protein. (88 aa)
	ENSAPLP00000019478	Uncharacterized protein. (234 aa)
	RPL3L	Ribosomal protein L3 like; Belongs to the universal ribosomal protein uL3 family. (462 aa)
	EIF5B	Eukaryotic translation initiation factor 5B. (1088 aa)
	ENSAPLP00000019845	Uncharacterized protein. (83 aa)
	RPLP1	Ribosomal protein lateral stalk subunit P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (114 aa)
	EIF1AY	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (166 aa)
	RPS24	40S ribosomal protein S24; Belongs to the eukaryotic ribosomal protein eS24 family. (132 aa)
	MRNIP	Uncharacterized protein. (367 aa)
	EIF3K	Eukaryotic translation initiation factor 3 subunit K. (123 aa)
	ENSAPLP00000022443	Ribosomal_S4 domain-containing protein. (96 aa)
	EIF3L	Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (653 aa)
	ENSAPLP00000022907	PCI domain-containing protein; Belongs to the eIF-3 subunit C family. (305 aa)
	ENSAPLP00000023310	Uncharacterized protein. (71 aa)
	RPL22L1	Ribosomal protein L22 like 1. (139 aa)
	ENSAPLP00000023790	Ribosomal_L7Ae domain-containing protein. (132 aa)
	RPL13	60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (213 aa)
	ENSAPLP00000024315	Uncharacterized protein. (157 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL6IP1	EIF1AY	ENSAPLP00000011486	ENSAPLP00000021191	Uncharacterized protein.	S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.975
ARL6IP1	EIF2S1	ENSAPLP00000011486	ENSAPLP00000027807	Uncharacterized protein.	Eukaryotic translation initiation factor 2 subunit alpha.	0.914
ARL6IP1	EIF2S2	ENSAPLP00000011486	ENSAPLP00000013066	Uncharacterized protein.	Eukaryotic translation initiation factor 2 subunit beta.	0.851
ARL6IP1	EIF2S3	ENSAPLP00000011486	ENSAPLP00000011244	Uncharacterized protein.	Tr-type G domain-containing protein.	0.883
ARL6IP1	EIF3A	ENSAPLP00000011486	ENSAPLP00000006298	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.910
ARL6IP1	EIF3B	ENSAPLP00000011486	ENSAPLP00000029927	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	0.894
ARL6IP1	EIF3D	ENSAPLP00000011486	ENSAPLP00000002086	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit D.	0.848
ARL6IP1	EIF3E	ENSAPLP00000011486	ENSAPLP00000005727	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.862
ARL6IP1	EIF3F	ENSAPLP00000011486	ENSAPLP00000016754	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.840
ARL6IP1	EIF3G	ENSAPLP00000011486	ENSAPLP00000024988	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.	0.855
ARL6IP1	EIF3H	ENSAPLP00000011486	ENSAPLP00000028487	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.838
ARL6IP1	EIF3I	ENSAPLP00000011486	ENSAPLP00000013288	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.879
ARL6IP1	EIF3J	ENSAPLP00000011486	ENSAPLP00000008143	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.869
ARL6IP1	EIF3K	ENSAPLP00000011486	ENSAPLP00000022317	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit K.	0.849
ARL6IP1	EIF3L	ENSAPLP00000011486	ENSAPLP00000022780	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.808
ARL6IP1	EIF3M	ENSAPLP00000011486	ENSAPLP00000005841	Uncharacterized protein.	Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.844
ARL6IP1	EIF4A2	ENSAPLP00000011486	ENSAPLP00000006403	Uncharacterized protein.	Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.	0.429
ARL6IP1	EIF4H	ENSAPLP00000011486	ENSAPLP00000008874	Uncharacterized protein.	Eukaryotic translation initiation factor 4H.	0.401
ARL6IP1	EIF5	ENSAPLP00000011486	ENSAPLP00000025941	Uncharacterized protein.	Eukaryotic translation initiation factor 5.	0.819
ARL6IP1	EIF5B	ENSAPLP00000011486	ENSAPLP00000019687	Uncharacterized protein.	Eukaryotic translation initiation factor 5B.	0.753