STRINGSTRING
RASGRF2 RASGRF2 U3HZQ3_ANAPP U3HZQ3_ANAPP OMG OMG TNFAIP3 TNFAIP3 U3I3J8_ANAPP U3I3J8_ANAPP SESTD1 SESTD1 ULK2 ULK2 STUB1 STUB1 ARHGEF9 ARHGEF9 OTUD7B OTUD7B OPTN OPTN SMPD3 SMPD3 UBE2L3 UBE2L3 CASP2 CASP2 FADD FADD U3IBK2_ANAPP U3IBK2_ANAPP FASLG FASLG RPS27A RPS27A BIRC2 BIRC2 U3IDI2_ANAPP U3IDI2_ANAPP AATF AATF PLEKHG5 PLEKHG5 ARHGDIA ARHGDIA LINGO2 LINGO2 USP2 USP2 ARHGEF7 ARHGEF7 UBE2D3 UBE2D3 PREX1 PREX1 CLIP4 CLIP4 ENSAPLP00000030759 ENSAPLP00000030759 ENSAPLP00000030426 ENSAPLP00000030426 IKBKB IKBKB ARHGEF3 ARHGEF3 PSEN2 PSEN2 ENSAPLP00000029278 ENSAPLP00000029278 ITGB3BP ITGB3BP FGD4 FGD4 SQSTM1 SQSTM1 MYD88 MYD88 ENSAPLP00000027962 ENSAPLP00000027962 MCF2 MCF2 TRAF6 TRAF6 TGM6 TGM6 TRAF1 TRAF1 CYLD CYLD FGD2 FGD2 VAV1 VAV1 ENSAPLP00000025878 ENSAPLP00000025878 VAV3 VAV3 UBE2D2 UBE2D2 ENSAPLP00000025444 ENSAPLP00000025444 TAX1BP1 TAX1BP1 XIAP XIAP ENSAPLP00000024578 ENSAPLP00000024578 ABR ABR TRADD TRADD ENSAPLP00000024412 ENSAPLP00000024412 ENSAPLP00000024408 ENSAPLP00000024408 OBSL1 OBSL1 TRAF2 TRAF2 MCF2L MCF2L ENSAPLP00000023897 ENSAPLP00000023897 VAV2 VAV2 ENSAPLP00000023562 ENSAPLP00000023562 RACK1 RACK1 TIAM2 TIAM2 ENSAPLP00000023086 ENSAPLP00000023086 ARHGEF4 ARHGEF4 SOS2 SOS2 ENSAPLP00000022550 ENSAPLP00000022550 ENSAPLP00000022326 ENSAPLP00000022326 CCDC71L CCDC71L NGFR NGFR LINGO1 LINGO1 WDR31 WDR31 ENSAPLP00000021206 ENSAPLP00000021206 OTULINL OTULINL AKAP13 AKAP13 ENSAPLP00000019809 ENSAPLP00000019809 TIAM1 TIAM1 ENSAPLP00000019469 ENSAPLP00000019469 FAS FAS ECT2 ECT2 USP21 USP21 ARHGEF39 ARHGEF39 ENSAPLP00000018970 ENSAPLP00000018970 KXD1 KXD1 ENSAPLP00000018628 ENSAPLP00000018628 ARHGEF5 ARHGEF5 NET1 NET1 MAPK8 MAPK8 NFKB1 NFKB1 UBE2D1 UBE2D1 PSEN1 PSEN1 NGF NGF OTUD1 OTUD1 ENSAPLP00000016784 ENSAPLP00000016784 TNFSF10 TNFSF10 SPPL2A SPPL2A BIRC7 BIRC7 ARHGEF18 ARHGEF18 FGD3 FGD3 RIPK1 RIPK1 U3J6Z6_ANAPP U3J6Z6_ANAPP MAPKAPK2 MAPKAPK2 CFLAR CFLAR CASP10 CASP10 U3J6D9_ANAPP U3J6D9_ANAPP CASP3 CASP3 ARHGEF12 ARHGEF12 USP4 USP4 CASP8 CASP8 ULK1 ULK1 NCSTN NCSTN SPATA2 SPATA2 IKBKE IKBKE NGEF NGEF MAP3K20 MAP3K20 U3J0U5_ANAPP U3J0U5_ANAPP ARHGEF26 ARHGEF26 GSAP GSAP SPPL2B SPPL2B ARHGEF6 ARHGEF6 ARHGEF33 ARHGEF33 MIB2 MIB2 ARHGEF11 ARHGEF11 ARHGEF38 ARHGEF38 SOS1 SOS1 ARHGEF37 ARHGEF37 U3IRT3_ANAPP U3IRT3_ANAPP PRDM4 PRDM4 NSMAF NSMAF U3IMS8_ANAPP U3IMS8_ANAPP TRIO TRIO TBK1 TBK1 ARHGEF17 ARHGEF17 PRKCI PRKCI MAP3K20-2 MAP3K20-2 MCF2L2 MCF2L2 ADAM17 ADAM17 ITSN1 ITSN1 RIPK2 RIPK2 KALRN KALRN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RASGRF2Ras protein specific guanine nucleotide releasing factor 2. (1238 aa)
U3HZQ3_ANAPPUncharacterized protein; Belongs to the peptidase C14A family. (268 aa)
OMGOligodendrocyte myelin glycoprotein. (428 aa)
TNFAIP3TNF alpha induced protein 3. (870 aa)
U3I3J8_ANAPPUncharacterized protein. (207 aa)
SESTD1SEC14 and spectrin domain containing 1. (695 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1077 aa)
STUB1STIP1 homology and U-box containing protein 1. (330 aa)
ARHGEF9Cdc42 guanine nucleotide exchange factor 9. (513 aa)
OTUD7BOTU deubiquitinase 7B. (918 aa)
OPTNOptineurin. (556 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (662 aa)
UBE2L3Ubiquitin conjugating enzyme E2 L3; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
CASP2Caspase 2; Belongs to the peptidase C14A family. (426 aa)
FADDUncharacterized protein. (195 aa)
U3IBK2_ANAPPUncharacterized protein. (566 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (237 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
BIRC2Uncharacterized protein. (611 aa)
U3IDI2_ANAPPUncharacterized protein. (357 aa)
AATFApoptosis antagonizing transcription factor. (560 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (489 aa)
ARHGDIARho GDP dissociation inhibitor alpha. (277 aa)
LINGO2Leucine rich repeat and Ig domain containing 2. (606 aa)
USP2Ubiquitin specific peptidase 2; Belongs to the peptidase C19 family. (450 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (843 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1662 aa)
CLIP4CAP-Gly domain containing linker protein family member 4. (710 aa)
ENSAPLP00000030759DUF4203 domain-containing protein. (244 aa)
ENSAPLP00000030426DH domain-containing protein. (255 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (778 aa)
ARHGEF3Rho guanine nucleotide exchange factor 3. (673 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
ENSAPLP00000029278DH domain-containing protein. (269 aa)
ITGB3BPIntegrin subunit beta 3 binding protein. (192 aa)
FGD4FYVE, RhoGEF and PH domain containing 4. (1113 aa)
SQSTM1Uncharacterized protein. (77 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
ENSAPLP00000027962Uncharacterized protein. (328 aa)
MCF2MCF.2 cell line derived transforming sequence. (1149 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
TGM6Transglutaminase 6. (713 aa)
TRAF1TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (570 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (970 aa)
FGD2FYVE, RhoGEF and PH domain containing 2. (624 aa)
VAV1Calponin-homology (CH) domain-containing protein. (81 aa)
ENSAPLP00000025878Uncharacterized protein. (339 aa)
VAV3Vav guanine nucleotide exchange factor 3. (790 aa)
UBE2D2Ubiquitin conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSAPLP00000025444DH domain-containing protein. (1335 aa)
TAX1BP1Tax1 binding protein 1. (816 aa)
XIAPX-linked inhibitor of apoptosis. (493 aa)
ENSAPLP00000024578Uncharacterized protein. (635 aa)
ABRRho-GAP domain-containing protein. (155 aa)
TRADDTNFRSF1A associated via death domain. (429 aa)
ENSAPLP00000024412Death domain-containing protein. (197 aa)
ENSAPLP00000024408Uncharacterized protein. (442 aa)
OBSL1Obscurin like 1. (2172 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (533 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1189 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
VAV2Vav guanine nucleotide exchange factor 2. (854 aa)
ENSAPLP00000023562Protein kinase domain-containing protein. (98 aa)
RACK1WD_REPEATS_REGION domain-containing protein. (101 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1724 aa)
ENSAPLP00000023086TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (323 aa)
ARHGEF4Uncharacterized protein. (2294 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1331 aa)
ENSAPLP00000022550WD_REPEATS_REGION domain-containing protein. (169 aa)
ENSAPLP00000022326Uncharacterized protein. (263 aa)
CCDC71LCoiled-coil domain containing 71 like. (453 aa)
NGFRUncharacterized protein. (181 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (792 aa)
WDR31WD repeat domain 31. (353 aa)
ENSAPLP00000021206DUF4203 domain-containing protein. (110 aa)
OTULINLOTU deubiquitinase with linear linkage specificity like. (429 aa)
AKAP13A-kinase anchoring protein 13. (2774 aa)
ENSAPLP00000019809Endo/exonuclease/phosphatase domain-containing protein. (685 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1432 aa)
ENSAPLP00000019469Uncharacterized protein. (318 aa)
FASUncharacterized protein. (461 aa)
ECT2Epithelial cell transforming 2. (914 aa)
USP21Ubiquitin specific peptidase 21. (329 aa)
ARHGEF39Rho guanine nucleotide exchange factor 39. (437 aa)
ENSAPLP00000018970TGc domain-containing protein. (695 aa)
KXD1KxDL motif containing 1. (353 aa)
ENSAPLP00000018628Uncharacterized protein. (90 aa)
ARHGEF5Uncharacterized protein. (1542 aa)
NET1Neuroepithelial cell transforming 1. (591 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
NFKB1Nuclear factor kappa B subunit 1. (998 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1. (97 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (293 aa)
OTUD1OTU deubiquitinase 1. (339 aa)
ENSAPLP00000016784WD_REPEATS_REGION domain-containing protein. (144 aa)
TNFSF10TNF superfamily member 10; Belongs to the tumor necrosis factor family. (295 aa)
SPPL2ASignal peptide peptidase like 2A. (537 aa)
BIRC7Baculoviral IAP repeat containing 7. (440 aa)
ARHGEF18Uncharacterized protein. (1015 aa)
FGD3FYVE, RhoGEF and PH domain containing 3. (712 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (690 aa)
U3J6Z6_ANAPPUncharacterized protein. (427 aa)
MAPKAPK2MAPK activated protein kinase 2. (397 aa)
CFLARCASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family. (489 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (538 aa)
U3J6D9_ANAPPUncharacterized protein; Belongs to the peptidase C14A family. (457 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (306 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1548 aa)
USP4Ubiquitin carboxyl-terminal hydrolase. (956 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (466 aa)
ULK1Unc-51 like autophagy activating kinase 1. (753 aa)
NCSTNNicastrin. (719 aa)
SPATA2Spermatogenesis associated 2. (481 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (725 aa)
NGEFUncharacterized protein. (741 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (452 aa)
U3J0U5_ANAPPDH domain-containing protein. (376 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (843 aa)
GSAPGamma-secretase activating protein. (846 aa)
SPPL2BSignal peptide peptidase like 2B. (597 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (731 aa)
ARHGEF33Rho guanine nucleotide exchange factor 33. (825 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (958 aa)
ARHGEF11RGS domain-containing protein. (576 aa)
ARHGEF38Rho guanine nucleotide exchange factor 38. (882 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1323 aa)
ARHGEF37Rho guanine nucleotide exchange factor 37. (686 aa)
U3IRT3_ANAPPTGc domain-containing protein. (653 aa)
PRDM4PR/SET domain 4. (828 aa)
NSMAFNeutral sphingomyelinase activation associated factor. (916 aa)
U3IMS8_ANAPPUncharacterized protein; Belongs to the peptidase C19 family. (807 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (2201 aa)
TBK1TANK binding kinase 1. (600 aa)
ARHGEF17Uncharacterized protein. (672 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
MAP3K20-2SAM domain-containing protein. (549 aa)
MCF2L2MCF.2 cell line derived transforming sequence-like 2. (836 aa)
ADAM17ADAM metallopeptidase domain 17. (836 aa)
ITSN1Intersectin 1. (1712 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (552 aa)
KALRNKalirin RhoGEF kinase. (2922 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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