51 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RFC2	Replication factor C subunit 2. (352 aa)
	POLH	DNA polymerase eta. (679 aa)
	USP1	Ubiquitin specific peptidase 1; Belongs to the peptidase C19 family. (303 aa)
	RPA2	Replication protein A2. (269 aa)
	RAD18	RAD18 E3 ubiquitin protein ligase. (501 aa)
	RFC5	Replication factor C subunit 5. (211 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1. (757 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (855 aa)
	POLK	DNA polymerase kappa. (866 aa)
	POLD3	Uncharacterized protein. (464 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	U3IG37_ANAPP	ATPase_AAA_core domain-containing protein. (1104 aa)
	RNF135	B30.2/SPRY domain-containing protein. (249 aa)
	SPATA5	Spermatogenesis associated 5. (1121 aa)
	DDB1	Damage specific DNA binding protein 1. (1050 aa)
	RFC4	Replication factor C subunit 4. (362 aa)
	POLE2	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
	MEIOB	Meiosis specific with OB-fold. (476 aa)
	MAD2L2	Mitotic arrest deficient 2 like 2. (211 aa)
	POLE	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2285 aa)
	RFC3	Replication factor C subunit 3. (356 aa)
	RBX1	Ring-box 1. (108 aa)
	RFC1	Replication factor C subunit 1. (1145 aa)
	WDR48	WD repeat domain 48. (678 aa)
	SPRTN	SprT-like N-terminal domain. (509 aa)
	USP31	Ubiquitin specific peptidase 31; Belongs to the peptidase C19 family. (1190 aa)
	RCHY1	Ring finger and CHY zinc finger domain containing 1. (289 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (726 aa)
	POLI	DNA polymerase iota. (799 aa)
	KXD1	KxDL motif containing 1. (353 aa)
	TRIM25	Tripartite motif containing 25. (648 aa)
	RCBTB2	RCC1 and BTB domain containing protein 2. (551 aa)
	UFD1	Ubiquitin recognition factor in ER associated degradation 1. (318 aa)
	ENSAPLP00000019203	UBIQUITIN_CONJUGAT_2 domain-containing protein. (143 aa)
	REV1	DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1282 aa)
	CUL4B	Cullin 4B; Belongs to the cullin family. (886 aa)
	CUL4A	Cullin 4A; Belongs to the cullin family. (617 aa)
	POLD2	DNA polymerase delta 2, accessory subunit. (554 aa)
	REV3L	Uncharacterized protein. (560 aa)
	ATAD5	Uncharacterized protein. (587 aa)
	USP10	Ubiquitin carboxyl-terminal hydrolase. (799 aa)
	ENSAPLP00000023729	Uncharacterized protein. (611 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	RCBTB1	RCC1 and BTB domain containing protein 1. (713 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (123 aa)
	ENSAPLP00000026666	DNA_pol_B domain-containing protein. (391 aa)
	NPLOC4	UN_NPL4 domain-containing protein. (129 aa)
	PCNA	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (262 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (685 aa)
	RPA3	Replication protein A3. (132 aa)
	POLE3	CBFD_NFYB_HMF domain-containing protein. (143 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	CUL4A	ENSAPLP00000023421	ENSAPLP00000021110	Uncharacterized protein.	Cullin 4A; Belongs to the cullin family.	0.421
ATAD5	CUL4B	ENSAPLP00000023421	ENSAPLP00000020411	Uncharacterized protein.	Cullin 4B; Belongs to the cullin family.	0.421
ATAD5	DDB1	ENSAPLP00000023421	ENSAPLP00000006857	Uncharacterized protein.	Damage specific DNA binding protein 1.	0.538
ATAD5	DTL	ENSAPLP00000023421	ENSAPLP00000015956	Uncharacterized protein.	Denticleless E3 ubiquitin protein ligase homolog.	0.733
ATAD5	ENSAPLP00000019203	ENSAPLP00000023421	ENSAPLP00000019203	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.416
ATAD5	ENSAPLP00000023897	ENSAPLP00000023421	ENSAPLP00000023897	Uncharacterized protein.	Uncharacterized protein.	0.411
ATAD5	ENSAPLP00000026666	ENSAPLP00000023421	ENSAPLP00000026666	Uncharacterized protein.	DNA_pol_B domain-containing protein.	0.570
ATAD5	MAD2L2	ENSAPLP00000023421	ENSAPLP00000009219	Uncharacterized protein.	Mitotic arrest deficient 2 like 2.	0.574
ATAD5	MEIOB	ENSAPLP00000023421	ENSAPLP00000007994	Uncharacterized protein.	Meiosis specific with OB-fold.	0.675
ATAD5	PCNA	ENSAPLP00000023421	ENSAPLP00000028238	Uncharacterized protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.914
ATAD5	POLD2	ENSAPLP00000023421	ENSAPLP00000021348	Uncharacterized protein.	DNA polymerase delta 2, accessory subunit.	0.616
ATAD5	POLD3	ENSAPLP00000023421	ENSAPLP00000004807	Uncharacterized protein.	Uncharacterized protein.	0.468
ATAD5	POLE	ENSAPLP00000023421	ENSAPLP00000009758	Uncharacterized protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.793
ATAD5	POLE2	ENSAPLP00000023421	ENSAPLP00000007103	Uncharacterized protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.749
ATAD5	POLE3	ENSAPLP00000023421	ENSAPLP00000032083	Uncharacterized protein.	CBFD_NFYB_HMF domain-containing protein.	0.682
ATAD5	POLE4	ENSAPLP00000023421	ENSAPLP00000025999	Uncharacterized protein.	DNA polymerase epsilon 4, accessory subunit.	0.643
ATAD5	POLH	ENSAPLP00000023421	ENSAPLP00000000581	Uncharacterized protein.	DNA polymerase eta.	0.524
ATAD5	POLI	ENSAPLP00000023421	ENSAPLP00000018250	Uncharacterized protein.	DNA polymerase iota.	0.482
ATAD5	POLK	ENSAPLP00000023421	ENSAPLP00000004615	Uncharacterized protein.	DNA polymerase kappa.	0.583
ATAD5	RAD18	ENSAPLP00000023421	ENSAPLP00000002608	Uncharacterized protein.	RAD18 E3 ubiquitin protein ligase.	0.754