47 items (Anas platyrhynchos) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOCS1	Suppressor of cytokine signaling 1. (207 aa)
	IFNGR1	Interferon gamma receptor 1. (438 aa)
	PRKCD	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
	TRIM42	Tripartite motif containing 42. (732 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (607 aa)
	TRIM14	Tripartite motif containing 14. (424 aa)
	IRF5	IRF-3 domain-containing protein. (174 aa)
	U3IGU3_ANAPP	B30.2/SPRY domain-containing protein. (185 aa)
	CAMK2G	Calcium/calmodulin dependent protein kinase II gamma; Belongs to the protein kinase superfamily. (465 aa)
	IRF6	Interferon regulatory factor 6. (467 aa)
	U3IPW4_ANAPP	GB1/RHD3-type G domain-containing protein. (239 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (432 aa)
	IRF1	Interferon regulatory factor 1. (439 aa)
	IRF8	IRF-3 domain-containing protein. (306 aa)
	IFNGR2	Interferon gamma receptor 2. (338 aa)
	SOCS3	Suppressor of cytokine signaling 3. (209 aa)
	JAK1	Tyrosine-protein kinase. (1152 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
	STAT1	Signal transducer and activator of transcription. (869 aa)
	ATL2	Atlastin GTPase 2. (576 aa)
	U3J6E8_ANAPP	Apovitellenin-1; Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes. (106 aa)
	TRIM45	Tripartite motif containing 45. (492 aa)
	MID2	Midline 2. (687 aa)
	IRF2	Interferon regulatory factor 2. (433 aa)
	ENSAPLP00000017670	GB1/RHD3-type G domain-containing protein. (404 aa)
	FOXS1	Forkhead box S1. (330 aa)
	ENSAPLP00000021789	Protein kinase domain-containing protein. (272 aa)
	ENSAPLP00000022207	IRF tryptophan pentad repeat domain-containing protein. (74 aa)
	SUMO1	Small ubiquitin like modifier 1. (242 aa)
	MID1	Midline 1. (667 aa)
	ATL1	Atlastin GTPase 1. (567 aa)
	ENSAPLP00000024821	IRF tryptophan pentad repeat domain-containing protein. (378 aa)
	ENSAPLP00000025168	GB1/RHD3-type G domain-containing protein. (337 aa)
	ENSAPLP00000025488	GB1/RHD3-type G domain-containing protein. (634 aa)
	ENSAPLP00000025779	GB1/RHD3-type G domain-containing protein. (226 aa)
	ENSAPLP00000025909	Uncharacterized protein. (659 aa)
	TRIM2	Tripartite motif containing 2. (744 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (744 aa)
	CIITA	NACHT domain-containing protein. (1109 aa)
	ENSAPLP00000029703	IRF tryptophan pentad repeat domain-containing protein. (143 aa)
	ENSAPLP00000029980	Uncharacterized protein. (148 aa)
	ENSAPLP00000030066	IRF-3 domain-containing protein. (225 aa)
	ENSAPLP00000030343	GB1/RHD3-type G domain-containing protein. (228 aa)
	IRF4	Interferon regulatory factor 4. (446 aa)
	TRIM3	Tripartite motif containing 3. (522 aa)
	ENSAPLP00000031669	IRF tryptophan pentad repeat domain-containing protein. (61 aa)
	CAMK2D	Protein kinase domain-containing protein. (355 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMK2D	ENSAPLP00000021789	ENSAPLP00000031887	ENSAPLP00000021789	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.700
ENSAPLP00000017670	ENSAPLP00000025779	ENSAPLP00000017670	ENSAPLP00000025779	GB1/RHD3-type G domain-containing protein.	GB1/RHD3-type G domain-containing protein.	0.946
ENSAPLP00000017670	ENSAPLP00000030343	ENSAPLP00000017670	ENSAPLP00000030343	GB1/RHD3-type G domain-containing protein.	GB1/RHD3-type G domain-containing protein.	0.946
ENSAPLP00000021789	CAMK2D	ENSAPLP00000021789	ENSAPLP00000031887	Protein kinase domain-containing protein.	Protein kinase domain-containing protein.	0.700
ENSAPLP00000024821	IRF1	ENSAPLP00000024821	ENSAPLP00000009421	IRF tryptophan pentad repeat domain-containing protein.	Interferon regulatory factor 1.	0.472
ENSAPLP00000025779	ENSAPLP00000017670	ENSAPLP00000025779	ENSAPLP00000017670	GB1/RHD3-type G domain-containing protein.	GB1/RHD3-type G domain-containing protein.	0.946
ENSAPLP00000025779	U3IPW4_ANAPP	ENSAPLP00000025779	ENSAPLP00000009287	GB1/RHD3-type G domain-containing protein.	GB1/RHD3-type G domain-containing protein.	0.947
ENSAPLP00000029703	IRF1	ENSAPLP00000029703	ENSAPLP00000009421	IRF tryptophan pentad repeat domain-containing protein.	Interferon regulatory factor 1.	0.439
ENSAPLP00000029980	U3IGU3_ANAPP	ENSAPLP00000029980	ENSAPLP00000006465	Uncharacterized protein.	B30.2/SPRY domain-containing protein.	0.900
ENSAPLP00000030066	IRF1	ENSAPLP00000030066	ENSAPLP00000009421	IRF-3 domain-containing protein.	Interferon regulatory factor 1.	0.410
ENSAPLP00000030066	STAT1	ENSAPLP00000030066	ENSAPLP00000013135	IRF-3 domain-containing protein.	Signal transducer and activator of transcription.	0.660
ENSAPLP00000030343	ENSAPLP00000017670	ENSAPLP00000030343	ENSAPLP00000017670	GB1/RHD3-type G domain-containing protein.	GB1/RHD3-type G domain-containing protein.	0.946
ENSAPLP00000030343	U3IPW4_ANAPP	ENSAPLP00000030343	ENSAPLP00000009287	GB1/RHD3-type G domain-containing protein.	GB1/RHD3-type G domain-containing protein.	0.947
IFNG	IFNGR1	ENSAPLP00000012661	ENSAPLP00000001484	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interferon gamma receptor 1.	0.998
IFNG	IFNGR2	ENSAPLP00000012661	ENSAPLP00000010983	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interferon gamma receptor 2.	0.998
IFNG	IRF1	ENSAPLP00000012661	ENSAPLP00000009421	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Interferon regulatory factor 1.	0.660
IFNG	IRF5	ENSAPLP00000012661	ENSAPLP00000005791	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	IRF-3 domain-containing protein.	0.515
IFNG	IRF8	ENSAPLP00000012661	ENSAPLP00000010093	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	IRF-3 domain-containing protein.	0.408
IFNG	JAK1	ENSAPLP00000012661	ENSAPLP00000011906	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Tyrosine-protein kinase.	0.789
IFNG	PRKCD	ENSAPLP00000012661	ENSAPLP00000002189	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.431