22 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1182 aa)
	PTPN12	Protein tyrosine phosphatase non-receptor type 12. (789 aa)
	EREG	Epiregulin. (148 aa)
	CUL5	Cullin 5; Belongs to the cullin family. (780 aa)
	NRG2	Neuregulin 2. (540 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSAPLP00000016792	Protein kinase domain-containing protein. (206 aa)
	NRG1	Neuregulin 1. (685 aa)
	EGFR	Receptor protein-tyrosine kinase. (1219 aa)
	USP8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1149 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (330 aa)
	ENSAPLP00000017981	Receptor protein-tyrosine kinase. (513 aa)
	NRG3	Neuregulin 3. (346 aa)
	RNF41	Ring finger protein 41. (317 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	BTC	EGF-like domain-containing protein. (417 aa)
	ERBB4	Receptor protein-tyrosine kinase. (1317 aa)
	NRG4	Neuregulin 4. (115 aa)
	ENSAPLP00000030500	Protein kinase domain-containing protein. (80 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	MATK	Tyrosine-protein kinase. (447 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT3	ENSAPLP00000016229	ENSAPLP00000011266	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	MATK	ENSAPLP00000016229	ENSAPLP00000002785	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.401
AKT1	USP8	ENSAPLP00000016229	ENSAPLP00000001332	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.531
AKT3	AKT1	ENSAPLP00000011266	ENSAPLP00000016229	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT3	MATK	ENSAPLP00000011266	ENSAPLP00000002785	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tyrosine-protein kinase.	0.401
AKT3	USP8	ENSAPLP00000011266	ENSAPLP00000001332	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.521
BTC	EGF	ENSAPLP00000027412	ENSAPLP00000011666	EGF-like domain-containing protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.724
BTC	EGFR	ENSAPLP00000027412	ENSAPLP00000002564	EGF-like domain-containing protein.	Receptor protein-tyrosine kinase.	0.951
BTC	ENSAPLP00000017981	ENSAPLP00000027412	ENSAPLP00000017981	EGF-like domain-containing protein.	Receptor protein-tyrosine kinase.	0.539
BTC	ERBB4	ENSAPLP00000027412	ENSAPLP00000028809	EGF-like domain-containing protein.	Receptor protein-tyrosine kinase.	0.975
BTC	EREG	ENSAPLP00000027412	ENSAPLP00000012792	EGF-like domain-containing protein.	Epiregulin.	0.928
BTC	NRG1	ENSAPLP00000027412	ENSAPLP00000017779	EGF-like domain-containing protein.	Neuregulin 1.	0.502
BTC	NRG2	ENSAPLP00000027412	ENSAPLP00000014937	EGF-like domain-containing protein.	Neuregulin 2.	0.616
CUL5	EGFR	ENSAPLP00000014921	ENSAPLP00000002564	Cullin 5; Belongs to the cullin family.	Receptor protein-tyrosine kinase.	0.439
CUL5	ENSAPLP00000017981	ENSAPLP00000014921	ENSAPLP00000017981	Cullin 5; Belongs to the cullin family.	Receptor protein-tyrosine kinase.	0.439
CUL5	ENSAPLP00000023897	ENSAPLP00000014921	ENSAPLP00000023897	Cullin 5; Belongs to the cullin family.	Uncharacterized protein.	0.721
CUL5	ERBB4	ENSAPLP00000014921	ENSAPLP00000028809	Cullin 5; Belongs to the cullin family.	Receptor protein-tyrosine kinase.	0.439
CUL5	RPS27A	ENSAPLP00000014921	ENSAPLP00000004982	Cullin 5; Belongs to the cullin family.	Ubiquitin-like domain-containing protein.	0.721
EGF	BTC	ENSAPLP00000011666	ENSAPLP00000027412	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	EGF-like domain-containing protein.	0.724
EGF	EGFR	ENSAPLP00000011666	ENSAPLP00000002564	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.998