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PCSK9 PCSK9 RPS27A RPS27A AP2M1 AP2M1 MYLIP MYLIP NR1H3 NR1H3 U3J7G1_ANAPP U3J7G1_ANAPP ENSAPLP00000016508 ENSAPLP00000016508 AP2A2 AP2A2 CLHC1 CLHC1 KXD1 KXD1 CLTA CLTA AP2B1 AP2B1 ENSAPLP00000023897 ENSAPLP00000023897 CLTC CLTC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCSK9Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (656 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (429 aa)
MYLIPMyosin regulatory light chain interacting protein. (445 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (409 aa)
U3J7G1_ANAPPUncharacterized protein. (861 aa)
ENSAPLP00000016508Uncharacterized protein. (182 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (552 aa)
KXD1KxDL motif containing 1. (353 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (247 aa)
AP2B1AP complex subunit beta. (951 aa)
ENSAPLP00000023897Uncharacterized protein. (208 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1676 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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