STRINGSTRING
GNG13 GNG13 ENSAPLP00000032859 ENSAPLP00000032859 ENSAPLP00000031941 ENSAPLP00000031941 KDM4B KDM4B GNG10 GNG10 ZDHHC21 ZDHHC21 TRPS1 TRPS1 ENSAPLP00000030836 ENSAPLP00000030836 KANK4 KANK4 NCOA3 NCOA3 CAV2 CAV2 ENSAPLP00000030500 ENSAPLP00000030500 ENSAPLP00000030475 ENSAPLP00000030475 POLR2E POLR2E ENSAPLP00000030173 ENSAPLP00000030173 GNG12 GNG12 HSPB1 HSPB1 EPGN EPGN CBFB CBFB ZDHHC7 ZDHHC7 ENSAPLP00000029576 ENSAPLP00000029576 POLR2H POLR2H ERBB4 ERBB4 CDKN1B CDKN1B PTGES3 PTGES3 CDK9 CDK9 GNG7 GNG7 ENSAPLP00000028423 ENSAPLP00000028423 ENSAPLP00000028245 ENSAPLP00000028245 KANK3 KANK3 ENSAPLP00000028132 ENSAPLP00000028132 POLR2D POLR2D ENSAPLP00000027877 ENSAPLP00000027877 GREB1 GREB1 BTC BTC TLE3 TLE3 ENSAPLP00000026997 ENSAPLP00000026997 ENSAPLP00000026892 ENSAPLP00000026892 ENSAPLP00000026741 ENSAPLP00000026741 STRN4 STRN4 GNG2 GNG2 FOXA2 FOXA2 ENSAPLP00000025272 ENSAPLP00000025272 CXXC5 CXXC5 FKBP5 FKBP5 POLR2L POLR2L AREG AREG CXXC4 CXXC4 CCNT1 CCNT1 ENSAPLP00000023040 ENSAPLP00000023040 ZNF217 ZNF217 JUND JUND GNG11 GNG11 FOS FOS ENSAPLP00000021857 ENSAPLP00000021857 ENSAPLP00000021501 ENSAPLP00000021501 ZC3H12C ZC3H12C CSDE1 CSDE1 POLR2B POLR2B FOXA1 FOXA1 KANK1 KANK1 ENSAPLP00000020328 ENSAPLP00000020328 GNAI3 GNAI3 CREBBP CREBBP ZC3H12A ZC3H12A HDAC1 HDAC1 UPK3BL1 UPK3BL1 SPHK1 SPHK1 YY1 YY1 ENSAPLP00000019251 ENSAPLP00000019251 ENSAPLP00000019176 ENSAPLP00000019176 KAT7 KAT7 ENSAPLP00000018432 ENSAPLP00000018432 ENSAPLP00000018398 ENSAPLP00000018398 PIK3R1 PIK3R1 PTK2 PTK2 NRIP1 NRIP1 POLR2K POLR2K GTF2A1L GTF2A1L HSP90AA1 HSP90AA1 GNB5 GNB5 ENSAPLP00000016792 ENSAPLP00000016792 ENSAPLP00000016714 ENSAPLP00000016714 AKT1 AKT1 STRN3 STRN3 KRAS KRAS PDPK1 PDPK1 HBEGF HBEGF POLR2F POLR2F UHMK1 UHMK1 PPID PPID NCOA1 NCOA1 EREG EREG PIK3CA PIK3CA TBP TBP GNGT2 GNGT2 HRAS HRAS GNB4 GNB4 FKBP4 FKBP4 KAT2B KAT2B ESR2 ESR2 EGF EGF PIK3R2 PIK3R2 AKT3 AKT3 FOXO3 FOXO3 KDM1A KDM1A GNB1 GNB1 STRN STRN EP300 EP300 PRKCZ PRKCZ GATA3 GATA3 GNAI2 GNAI2 H2BE1 H2BE1 NRAS NRAS DDX5 DDX5 PRMT8 PRMT8 SHC1 SHC1 IGF1R IGF1R ZC3H12D ZC3H12D TBPL1 TBPL1 MMP13 MMP13 TBPL2 TBPL2 U3IGX0_ANAPP U3IGX0_ANAPP CREB1 CREB1 GTF2A2 GTF2A2 GNG4 GNG4 MMP7 MMP7 POLR2C POLR2C GNAI1 GNAI1 ESR1 ESR1 GTF2F2 GTF2F2 GREB1L GREB1L PTGES3L PTGES3L XPO1 XPO1 PGR PGR U3I833_ANAPP U3I833_ANAPP ZC3H12B ZC3H12B MMP2 MMP2 POLR2J POLR2J H2AZ1 H2AZ1 GNB3 GNB3 H2AZ2 H2AZ2 EBAG9 EBAG9 GTF2A1 GTF2A1 U3I3E5_ANAPP U3I3E5_ANAPP U3I3A9_ANAPP U3I3A9_ANAPP CAV1 CAV1 S1PR3 S1PR3 GNG5 GNG5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNG13G protein subunit gamma 13. (67 aa)
ENSAPLP00000032859ZnMc domain-containing protein. (471 aa)
ENSAPLP00000031941Histone H2B; Belongs to the histone H2B family. (126 aa)
KDM4BLysine demethylase 4B. (1156 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
TRPS1Transcriptional repressor GATA binding 1. (1294 aa)
ENSAPLP00000030836Histone domain-containing protein. (86 aa)
KANK4KN motif and ankyrin repeat domains 4. (1002 aa)
NCOA3Nuclear receptor coactivator. (1401 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
ENSAPLP00000030500Protein kinase domain-containing protein. (80 aa)
ENSAPLP00000030475Recep_L_domain domain-containing protein. (267 aa)
POLR2ERNA polymerase II subunit E. (458 aa)
ENSAPLP00000030173Uncharacterized protein. (328 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
HSPB1SHSP domain-containing protein. (517 aa)
EPGNEpithelial mitogen. (151 aa)
CBFBCore-binding factor subunit beta. (80 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (394 aa)
ENSAPLP00000029576Histone H2B; Belongs to the histone H2B family. (126 aa)
POLR2HRNA polymerase II subunit H. (95 aa)
ERBB4Receptor protein-tyrosine kinase. (1317 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (362 aa)
PTGES3Prostaglandin E synthase 3. (342 aa)
CDK9Cyclin dependent kinase 9. (403 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
ENSAPLP00000028423Uncharacterized protein; Belongs to the histone H2B family. (122 aa)
ENSAPLP00000028245Uncharacterized protein. (71 aa)
KANK3ANK_REP_REGION domain-containing protein. (175 aa)
ENSAPLP00000028132Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (393 aa)
POLR2DRPOL4c domain-containing protein. (188 aa)
ENSAPLP00000027877Cyclin N-terminal domain-containing protein. (175 aa)
GREB1Uncharacterized protein. (1943 aa)
BTCEGF-like domain-containing protein. (417 aa)
TLE3TLE family member 3, transcriptional corepressor. (690 aa)
ENSAPLP00000026997Uncharacterized protein; Belongs to the histone H2B family. (145 aa)
ENSAPLP00000026892annotation not available (136 aa)
ENSAPLP00000026741BZIP domain-containing protein. (127 aa)
STRN4Striatin 4. (752 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
FOXA2Forkhead box A2. (449 aa)
ENSAPLP00000025272Uncharacterized protein. (374 aa)
CXXC5CXXC finger protein 5. (162 aa)
FKBP5Peptidylprolyl isomerase. (546 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
AREGAmphiregulin. (212 aa)
CXXC4CXXC finger protein 4. (385 aa)
CCNT1Cyclin T1. (653 aa)
ENSAPLP00000023040Uncharacterized protein. (136 aa)
ZNF217Zinc finger protein 217. (1076 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (300 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (369 aa)
ENSAPLP00000021857Histone H2A; Belongs to the histone H2A family. (129 aa)
ENSAPLP00000021501HATPase_c domain-containing protein. (244 aa)
ZC3H12CZinc finger CCCH-type containing 12C. (953 aa)
CSDE1Cold shock domain containing E1. (796 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1583 aa)
FOXA1Forkhead box A1. (464 aa)
KANK1KN motif and ankyrin repeat domains 1. (1359 aa)
ENSAPLP00000020328Uncharacterized protein; Belongs to the histone H2A family. (356 aa)
GNAI3G protein subunit alpha i3. (354 aa)
CREBBPCREB binding protein. (2396 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (675 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (506 aa)
UPK3BL1Uncharacterized protein. (328 aa)
SPHK1Sphingosine kinase 1. (778 aa)
YY1YY1 transcription factor. (420 aa)
ENSAPLP00000019251annotation not available (129 aa)
ENSAPLP00000019176annotation not available (125 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
ENSAPLP00000018432Uncharacterized protein. (108 aa)
ENSAPLP00000018398Importin N-terminal domain-containing protein. (289 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PTK2Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1119 aa)
NRIP1Nuclear receptor interacting protein 1. (1152 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
GTF2A1LGeneral transcription factor IIA subunit 1 like. (542 aa)
HSP90AA1Uncharacterized protein. (362 aa)
GNB5G protein subunit beta 5. (401 aa)
ENSAPLP00000016792Protein kinase domain-containing protein. (206 aa)
ENSAPLP00000016714FERM_N_2 domain-containing protein. (80 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
STRN3Striatin 3. (827 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
HBEGFHeparin binding EGF like growth factor. (378 aa)
POLR2FRNA polymerase II subunit F. (291 aa)
UHMK1U2AF homology motif kinase 1. (429 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
NCOA1Nuclear receptor coactivator. (1479 aa)
EREGEpiregulin. (148 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
TBPTATA-box binding protein. (302 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
GNB4G protein subunit beta 4. (343 aa)
FKBP4Peptidylprolyl isomerase. (449 aa)
KAT2BLysine acetyltransferase 2B. (856 aa)
ESR2Estrogen receptor 2. (554 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1182 aa)
PIK3R2Uncharacterized protein. (731 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
FOXO3Fork-head domain-containing protein. (665 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (829 aa)
GNB1G protein subunit beta 1. (372 aa)
STRNStriatin. (771 aa)
EP300E1A binding protein p300. (2355 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
GATA3GATA binding protein 3. (712 aa)
GNAI2G protein subunit alpha i2. (321 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (162 aa)
NRASUncharacterized protein. (189 aa)
DDX5DEAD-box helicase 5; Belongs to the DEAD box helicase family. (582 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (383 aa)
SHC1SHC adaptor protein 1. (616 aa)
IGF1RTyrosine-protein kinase receptor. (1363 aa)
ZC3H12DZinc finger CCCH-type containing 12D. (609 aa)
TBPL1TATA-box binding protein like 1. (183 aa)
MMP13Matrix metallopeptidase 13. (472 aa)
TBPL2TATA-box binding protein like 2. (326 aa)
U3IGX0_ANAPPUncharacterized protein. (463 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
MMP7Matrix metallopeptidase 7. (267 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
GNAI1G protein subunit alpha i1. (354 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (548 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (262 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1971 aa)
PTGES3LProstaglandin E synthase 3 like. (203 aa)
XPO1CRM1_C domain-containing protein. (564 aa)
PGRProgesterone receptor. (800 aa)
U3I833_ANAPPHistone H3; Belongs to the histone H3 family. (136 aa)
ZC3H12BZinc finger CCCH-type containing 12B. (837 aa)
MMP2Matrix metallopeptidase 2. (663 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (144 aa)
GNB3G protein subunit beta 3. (331 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (139 aa)
EBAG9Estrogen receptor binding site associated antigen 9; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (241 aa)
GTF2A1General transcription factor IIA subunit 1. (377 aa)
U3I3E5_ANAPPHistone H2A; Belongs to the histone H2A family. (129 aa)
U3I3A9_ANAPPHistone H2A; Belongs to the histone H2A family. (124 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (176 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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