31 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	U3I2I6_ANAPP	Protein kinase domain-containing protein. (184 aa)
	TCF3	Transcription factor 3. (627 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (656 aa)
	KMT2A	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (3782 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	CCNH	Cyclin H; Belongs to the cyclin family. (323 aa)
	LMO2	LIM domain only 2. (338 aa)
	LDB2	LIM domain binding 2. (362 aa)
	PSMA1	Proteasome subunit alpha type. (259 aa)
	MNAT1	MNAT1 component of CDK activating kinase. (336 aa)
	PSME4	BLM10_mid domain-containing protein. (581 aa)
	GATA3	GATA binding protein 3. (712 aa)
	LMO3	LIM domain only 3. (177 aa)
	LDB1	LIM domain binding 1. (225 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	ITCH	E3 ubiquitin-protein ligase. (769 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (945 aa)
	PSMD10	Proteasome 26S subunit, non-ATPase 10. (191 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
	ENSAPLP00000021459	Uncharacterized protein. (188 aa)
	ABL1	ABL proto-oncogene 1, non-receptor tyrosine kinase. (610 aa)
	ENSAPLP00000023558	Uncharacterized protein. (455 aa)
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	GATA2	Uncharacterized protein. (93 aa)
	SPI1	Spi-1 proto-oncogene. (202 aa)
	LMO1	LIM domain only 1. (280 aa)
	CDK7	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (409 aa)
	ENSAPLP00000026079	DUF3437 domain-containing protein. (220 aa)
	TAL2	TAL bHLH transcription factor 2. (177 aa)
	CBFB	Core-binding factor subunit beta. (80 aa)
	ENSAPLP00000031212	SH2 domain-containing protein. (71 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CBFB	ENSAPLP00000022843	ENSAPLP00000029667	ABL proto-oncogene 1, non-receptor tyrosine kinase.	Core-binding factor subunit beta.	0.426
ABL1	U3I2I6_ANAPP	ENSAPLP00000022843	ENSAPLP00000001456	ABL proto-oncogene 1, non-receptor tyrosine kinase.	Protein kinase domain-containing protein.	0.884
CBFB	ABL1	ENSAPLP00000029667	ENSAPLP00000022843	Core-binding factor subunit beta.	ABL proto-oncogene 1, non-receptor tyrosine kinase.	0.426
CBFB	CCNH	ENSAPLP00000029667	ENSAPLP00000005308	Core-binding factor subunit beta.	Cyclin H; Belongs to the cyclin family.	0.537
CBFB	CDK7	ENSAPLP00000029667	ENSAPLP00000025054	Core-binding factor subunit beta.	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	0.606
CBFB	ENSAPLP00000023558	ENSAPLP00000029667	ENSAPLP00000023558	Core-binding factor subunit beta.	Uncharacterized protein.	0.537
CBFB	ENSAPLP00000031212	ENSAPLP00000029667	ENSAPLP00000031212	Core-binding factor subunit beta.	SH2 domain-containing protein.	0.426
CBFB	GATA2	ENSAPLP00000029667	ENSAPLP00000024003	Core-binding factor subunit beta.	Uncharacterized protein.	0.537
CBFB	GATA3	ENSAPLP00000029667	ENSAPLP00000009770	Core-binding factor subunit beta.	GATA binding protein 3.	0.562
CBFB	KMT2A	ENSAPLP00000029667	ENSAPLP00000004456	Core-binding factor subunit beta.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.609
CBFB	LDB1	ENSAPLP00000029667	ENSAPLP00000012507	Core-binding factor subunit beta.	LIM domain binding 1.	0.588
CBFB	LDB2	ENSAPLP00000029667	ENSAPLP00000007286	Core-binding factor subunit beta.	LIM domain binding 2.	0.588
CBFB	LMO1	ENSAPLP00000029667	ENSAPLP00000024266	Core-binding factor subunit beta.	LIM domain only 1.	0.538
CBFB	LMO2	ENSAPLP00000029667	ENSAPLP00000006567	Core-binding factor subunit beta.	LIM domain only 2.	0.692
CBFB	LMO3	ENSAPLP00000029667	ENSAPLP00000010384	Core-binding factor subunit beta.	LIM domain only 3.	0.538
CBFB	TAL2	ENSAPLP00000029667	ENSAPLP00000028526	Core-binding factor subunit beta.	TAL bHLH transcription factor 2.	0.692
CBFB	TCF3	ENSAPLP00000029667	ENSAPLP00000001831	Core-binding factor subunit beta.	Transcription factor 3.	0.475
CBFB	U3I2I6_ANAPP	ENSAPLP00000029667	ENSAPLP00000001456	Core-binding factor subunit beta.	Protein kinase domain-containing protein.	0.426
CCNH	CBFB	ENSAPLP00000005308	ENSAPLP00000029667	Cyclin H; Belongs to the cyclin family.	Core-binding factor subunit beta.	0.537
CCNH	CDK7	ENSAPLP00000005308	ENSAPLP00000025054	Cyclin H; Belongs to the cyclin family.	Cyclin dependent kinase 7; Belongs to the protein kinase superfamily.	0.999