19 items (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPLP00000023897	Uncharacterized protein. (208 aa)
	NEURL1B	Neuralized E3 ubiquitin protein ligase 1B. (663 aa)
	TACC3	Transforming acidic coiled-coil containing protein 3. (903 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (465 aa)
	NCSTN	Nicastrin. (719 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (665 aa)
	ADAM10	ADAM metallopeptidase domain 10. (711 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1182 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (728 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1225 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	MIB1	Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
	NEURL1	Neuralized E3 ubiquitin protein ligase 1. (572 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1334 aa)
	NOTCH1	Uncharacterized protein. (2250 aa)
	ENSAPLP00000032550	Uncharacterized protein. (432 aa)
	ENSAPLP00000031373	C2 domain-containing protein. (210 aa)
	ENSAPLP00000028254	Uncharacterized protein. (320 aa)
	ENSAPLP00000024578	Uncharacterized protein. (635 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM10	DLL1	ENSAPLP00000013418	ENSAPLP00000011451	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.747
ADAM10	DLL4	ENSAPLP00000013418	ENSAPLP00000014039	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.508
ADAM10	EGF	ENSAPLP00000013418	ENSAPLP00000011666	ADAM metallopeptidase domain 10.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.496
ADAM10	ENSAPLP00000028254	ENSAPLP00000013418	ENSAPLP00000028254	ADAM metallopeptidase domain 10.	Uncharacterized protein.	0.565
ADAM10	JAG1	ENSAPLP00000013418	ENSAPLP00000009118	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.524
ADAM10	JAG2	ENSAPLP00000013418	ENSAPLP00000003765	ADAM metallopeptidase domain 10.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.489
ADAM10	NCSTN	ENSAPLP00000013418	ENSAPLP00000014633	ADAM metallopeptidase domain 10.	Nicastrin.	0.637
ADAM10	NOTCH1	ENSAPLP00000013418	ENSAPLP00000004270	ADAM metallopeptidase domain 10.	Uncharacterized protein.	0.565
ADAM10	PSEN1	ENSAPLP00000013418	ENSAPLP00000018025	ADAM metallopeptidase domain 10.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.646
DLL1	ADAM10	ENSAPLP00000011451	ENSAPLP00000013418	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	ADAM metallopeptidase domain 10.	0.747
DLL1	DLL4	ENSAPLP00000011451	ENSAPLP00000014039	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.421
DLL1	ENSAPLP00000028254	ENSAPLP00000011451	ENSAPLP00000028254	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.969
DLL1	JAG1	ENSAPLP00000011451	ENSAPLP00000009118	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.530
DLL1	JAG2	ENSAPLP00000011451	ENSAPLP00000003765	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.425
DLL1	MIB1	ENSAPLP00000011451	ENSAPLP00000004777	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mindbomb E3 ubiquitin protein ligase 1.	0.415
DLL1	NOTCH1	ENSAPLP00000011451	ENSAPLP00000004270	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.997
DLL4	ADAM10	ENSAPLP00000014039	ENSAPLP00000013418	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	ADAM metallopeptidase domain 10.	0.508
DLL4	DLL1	ENSAPLP00000014039	ENSAPLP00000011451	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.421
DLL4	EGF	ENSAPLP00000014039	ENSAPLP00000011666	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.467
DLL4	ENSAPLP00000028254	ENSAPLP00000014039	ENSAPLP00000028254	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.984