STRINGSTRING
TGFB2 TGFB2 IFNG IFNG IL10 IL10 GSR GSR CFTR CFTR CD4 CD4 H2BE1 H2BE1 IL21 IL21 U3IA97_ANAPP U3IA97_ANAPP U3I833_ANAPP U3I833_ANAPP VWF VWF TLR2 TLR2 ENSAPLP00000031941 ENSAPLP00000031941 ENO1 ENO1 NCK2 NCK2 ENSAPLP00000029576 ENSAPLP00000029576
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
IL10Interleukin 10. (177 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (464 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1548 aa)
CD4Ig-like domain-containing protein. (264 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (162 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (145 aa)
U3IA97_ANAPPPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (242 aa)
U3I833_ANAPPHistone H3; Belongs to the histone H3 family. (136 aa)
VWFVon Willebrand factor. (2756 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
ENSAPLP00000031941Histone H2B; Belongs to the histone H2B family. (126 aa)
ENO1Enolase_N domain-containing protein. (172 aa)
NCK2Cytoplasmic protein. (380 aa)
ENSAPLP00000029576Histone H2B; Belongs to the histone H2B family. (126 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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