(12 nodes) (2014) Dysregulated cytokine production by dendritic cells modulates B cell responses in the NZM2410 mouse model of lupus. network (Anas platyrhynchos)

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Your Input:
	CD40	TNFR-Cys domain-containing protein. (214 aa)
	MX1	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (721 aa)
	IL10	Interleukin 10. (177 aa)
	IFNG	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
	IL4	Uncharacterized protein. (136 aa)
	IL18	Interleukin-18. (197 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
	IL6	Uncharacterized protein. (350 aa)
	CD86	CD86 molecule. (341 aa)
	IRF7	Interferon regulatory factor 7. (523 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
	ENSAPLP00000028410	Uncharacterized protein. (157 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD40	CD86	ENSAPLP00000016411	ENSAPLP00000026026	TNFR-Cys domain-containing protein.	CD86 molecule.	0.965
CD40	IFNG	ENSAPLP00000016411	ENSAPLP00000012661	TNFR-Cys domain-containing protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.804
CD40	IL10	ENSAPLP00000016411	ENSAPLP00000015242	TNFR-Cys domain-containing protein.	Interleukin 10.	0.815
CD40	IL4	ENSAPLP00000016411	ENSAPLP00000011598	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.924
CD40	IL6	ENSAPLP00000016411	ENSAPLP00000020478	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.823
CD40	MYD88	ENSAPLP00000016411	ENSAPLP00000028214	TNFR-Cys domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.736
CD40	TLR7	ENSAPLP00000016411	ENSAPLP00000003630	TNFR-Cys domain-containing protein.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.738
CD86	CD40	ENSAPLP00000026026	ENSAPLP00000016411	CD86 molecule.	TNFR-Cys domain-containing protein.	0.965
CD86	IFNG	ENSAPLP00000026026	ENSAPLP00000012661	CD86 molecule.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.885
CD86	IL10	ENSAPLP00000026026	ENSAPLP00000015242	CD86 molecule.	Interleukin 10.	0.848
CD86	IL18	ENSAPLP00000026026	ENSAPLP00000005562	CD86 molecule.	Interleukin-18.	0.462
CD86	IL4	ENSAPLP00000026026	ENSAPLP00000011598	CD86 molecule.	Uncharacterized protein.	0.820
CD86	IL6	ENSAPLP00000026026	ENSAPLP00000020478	CD86 molecule.	Uncharacterized protein.	0.821
CD86	MYD88	ENSAPLP00000026026	ENSAPLP00000028214	CD86 molecule.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.738
CD86	TLR7	ENSAPLP00000026026	ENSAPLP00000003630	CD86 molecule.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.757
ENSAPLP00000028410	IFNG	ENSAPLP00000028410	ENSAPLP00000012661	Uncharacterized protein.	Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.	0.970
ENSAPLP00000028410	IL10	ENSAPLP00000028410	ENSAPLP00000015242	Uncharacterized protein.	Interleukin 10.	0.672
ENSAPLP00000028410	IL18	ENSAPLP00000028410	ENSAPLP00000005562	Uncharacterized protein.	Interleukin-18.	0.517
ENSAPLP00000028410	IL4	ENSAPLP00000028410	ENSAPLP00000011598	Uncharacterized protein.	Uncharacterized protein.	0.508
ENSAPLP00000028410	IL6	ENSAPLP00000028410	ENSAPLP00000020478	Uncharacterized protein.	Uncharacterized protein.	0.807