(5 nodes) (2014) High basal expression of interferon-stimulated genes in human bronchial epithelial (BEAS-2B) cells contributes to influenza A virus resistance. network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPLP00000029472	Uncharacterized protein. (1406 aa)
	ENSAPLP00000028410	Uncharacterized protein. (157 aa)
	IRF7	Interferon regulatory factor 7. (523 aa)
	IL6	Uncharacterized protein. (350 aa)
	PXDN	Peroxidasin. (1193 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000028410	IL6	ENSAPLP00000028410	ENSAPLP00000020478	Uncharacterized protein.	Uncharacterized protein.	0.807
ENSAPLP00000028410	IRF7	ENSAPLP00000028410	ENSAPLP00000026565	Uncharacterized protein.	Interferon regulatory factor 7.	0.961
ENSAPLP00000029472	IL6	ENSAPLP00000029472	ENSAPLP00000020478	Uncharacterized protein.	Uncharacterized protein.	0.758
ENSAPLP00000029472	PXDN	ENSAPLP00000029472	ENSAPLP00000015658	Uncharacterized protein.	Peroxidasin.	0.616
IL6	ENSAPLP00000028410	ENSAPLP00000020478	ENSAPLP00000028410	Uncharacterized protein.	Uncharacterized protein.	0.807
IL6	ENSAPLP00000029472	ENSAPLP00000020478	ENSAPLP00000029472	Uncharacterized protein.	Uncharacterized protein.	0.758
IL6	IRF7	ENSAPLP00000020478	ENSAPLP00000026565	Uncharacterized protein.	Interferon regulatory factor 7.	0.646
IL6	PXDN	ENSAPLP00000020478	ENSAPLP00000015658	Uncharacterized protein.	Peroxidasin.	0.758
IRF7	ENSAPLP00000028410	ENSAPLP00000026565	ENSAPLP00000028410	Interferon regulatory factor 7.	Uncharacterized protein.	0.961
IRF7	IL6	ENSAPLP00000026565	ENSAPLP00000020478	Interferon regulatory factor 7.	Uncharacterized protein.	0.646
PXDN	ENSAPLP00000029472	ENSAPLP00000015658	ENSAPLP00000029472	Peroxidasin.	Uncharacterized protein.	0.616
PXDN	IL6	ENSAPLP00000015658	ENSAPLP00000020478	Peroxidasin.	Uncharacterized protein.	0.758