(27 nodes) (2018) Induction and Subversion of Human Protective Immunity: Contrasting Influenza and Respiratory Syncytial Virus. network (Anas platyrhynchos)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL22	Interleukin 22. (197 aa)
	PDCD1	Ig-like domain-containing protein. (396 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (223 aa)
	IL18	Interleukin-18. (197 aa)
	IL-2	Interleukin; Belongs to the IL-15/IL-21 family. (140 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (914 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
	IL4	Uncharacterized protein. (136 aa)
	TLR4	Toll like receptor 4. (843 aa)
	STAT1	Signal transducer and activator of transcription. (869 aa)
	U3J1K3_ANAPP	Uncharacterized protein; Belongs to the peptidase C14A family. (284 aa)
	IL21R	Interleukin 21 receptor. (588 aa)
	IL10	Interleukin 10. (177 aa)
	MX1	MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (721 aa)
	CD4	Ig-like domain-containing protein. (264 aa)
	BCL6	Uncharacterized protein. (709 aa)
	IL6	Uncharacterized protein. (350 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (951 aa)
	IL-17	Uncharacterized protein. (191 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (311 aa)
	CCR10	C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (353 aa)
	RNASEL	Uncharacterized protein. (772 aa)
	MAVS	CARD_2 domain-containing protein. (619 aa)
	TBK1	TANK binding kinase 1. (600 aa)
	CX3CR1	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (378 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	CCR7	ENSAPLP00000018321	ENSAPLP00000007659	Uncharacterized protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.526
BCL6	CD4	ENSAPLP00000018321	ENSAPLP00000018005	Uncharacterized protein.	Ig-like domain-containing protein.	0.752
BCL6	IL-17	ENSAPLP00000018321	ENSAPLP00000026822	Uncharacterized protein.	Uncharacterized protein.	0.541
BCL6	IL10	ENSAPLP00000018321	ENSAPLP00000015242	Uncharacterized protein.	Interleukin 10.	0.429
BCL6	IL21R	ENSAPLP00000018321	ENSAPLP00000015142	Uncharacterized protein.	Interleukin 21 receptor.	0.673
BCL6	IL4	ENSAPLP00000018321	ENSAPLP00000011598	Uncharacterized protein.	Uncharacterized protein.	0.766
BCL6	IL6	ENSAPLP00000018321	ENSAPLP00000020478	Uncharacterized protein.	Uncharacterized protein.	0.509
BCL6	MYD88	ENSAPLP00000018321	ENSAPLP00000028214	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.475
BCL6	TLR7	ENSAPLP00000018321	ENSAPLP00000003630	Uncharacterized protein.	Toll like receptor 7; Belongs to the Toll-like receptor family.	0.482
CCR10	CCR7	ENSAPLP00000028709	ENSAPLP00000007659	C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.617
CCR7	BCL6	ENSAPLP00000007659	ENSAPLP00000018321	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.526
CCR7	CCR10	ENSAPLP00000007659	ENSAPLP00000028709	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family.	0.617
CCR7	CD4	ENSAPLP00000007659	ENSAPLP00000018005	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Ig-like domain-containing protein.	0.820
CCR7	CX3CR1	ENSAPLP00000007659	ENSAPLP00000000814	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family.	0.561
CCR7	IL-17	ENSAPLP00000007659	ENSAPLP00000026822	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.687
CCR7	IL10	ENSAPLP00000007659	ENSAPLP00000015242	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Interleukin 10.	0.701
CCR7	IL15	ENSAPLP00000007659	ENSAPLP00000004404	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Interleukin; Belongs to the IL-15/IL-21 family.	0.485
CCR7	IL4	ENSAPLP00000007659	ENSAPLP00000011598	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.668
CCR7	IL6	ENSAPLP00000007659	ENSAPLP00000020478	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.671
CCR7	NOD1	ENSAPLP00000007659	ENSAPLP00000023952	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Nucleotide binding oligomerization domain containing 1.	0.459