STRINGSTRING
MSL2 MSL2 PRKCD PRKCD MAVS MAVS SRPK1 SRPK1 NEDD4 NEDD4 AR AR SUMO2 SUMO2 DDB1 DDB1 STAT3 STAT3 PLK1 PLK1 IFNAR1 IFNAR1 STAT1 STAT1 MYC MYC SAMHD1 SAMHD1 BRD4 BRD4 HDAC1 HDAC1 CUL4B CUL4B IL6 IL6 CUL4A CUL4A PRMT3 PRMT3 SUMO1 SUMO1 SIAH1 SIAH1 STAT4 STAT4 PRKN PRKN TRIM32 TRIM32 ENSAPLP00000028410 ENSAPLP00000028410 SRPK2 SRPK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MSL2RING-type domain-containing protein. (579 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (703 aa)
MAVSCARD_2 domain-containing protein. (619 aa)
SRPK1SRSF protein kinase 1. (664 aa)
NEDD4E3 ubiquitin-protein ligase. (875 aa)
ARAndrogen receptor. (385 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
DDB1Damage specific DNA binding protein 1. (1050 aa)
STAT3Signal transducer and activator of transcription. (942 aa)
PLK1Serine/threonine-protein kinase PLK. (596 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (584 aa)
STAT1Signal transducer and activator of transcription. (869 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (418 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (573 aa)
BRD4BRD4_CDT domain-containing protein. (244 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (506 aa)
CUL4BCullin 4B; Belongs to the cullin family. (886 aa)
IL6Uncharacterized protein. (350 aa)
CUL4ACullin 4A; Belongs to the cullin family. (617 aa)
PRMT3Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (458 aa)
SUMO1Small ubiquitin like modifier 1. (242 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (341 aa)
STAT4Signal transducer and activator of transcription. (757 aa)
PRKNParkin RBR E3 ubiquitin protein ligase. (520 aa)
TRIM32Tripartite motif containing 32. (715 aa)
ENSAPLP00000028410Uncharacterized protein. (157 aa)
SRPK2SRSF protein kinase 2. (738 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (34%) [HD]