node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IFNG | TLR2 | ENSAPLP00000012661 | ENSAPLP00000011131 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Toll like receptor 2; Belongs to the Toll-like receptor family. | 0.495 |
IFNG | TLR3 | ENSAPLP00000012661 | ENSAPLP00000008663 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Toll like receptor 3; Belongs to the Toll-like receptor family. | 0.680 |
IFNG | TLR4 | ENSAPLP00000012661 | ENSAPLP00000012401 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Toll like receptor 4. | 0.783 |
IFNG | TLR5 | ENSAPLP00000012661 | ENSAPLP00000000694 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.422 |
IFNG | TLR7 | ENSAPLP00000012661 | ENSAPLP00000003630 | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | Toll like receptor 7; Belongs to the Toll-like receptor family. | 0.732 |
TLR2 | IFNG | ENSAPLP00000011131 | ENSAPLP00000012661 | Toll like receptor 2; Belongs to the Toll-like receptor family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.495 |
TLR2 | TLR3 | ENSAPLP00000011131 | ENSAPLP00000008663 | Toll like receptor 2; Belongs to the Toll-like receptor family. | Toll like receptor 3; Belongs to the Toll-like receptor family. | 0.455 |
TLR2 | TLR4 | ENSAPLP00000011131 | ENSAPLP00000012401 | Toll like receptor 2; Belongs to the Toll-like receptor family. | Toll like receptor 4. | 0.841 |
TLR2 | TLR5 | ENSAPLP00000011131 | ENSAPLP00000000694 | Toll like receptor 2; Belongs to the Toll-like receptor family. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.463 |
TLR2 | TLR6 | ENSAPLP00000011131 | ENSAPLP00000001470 | Toll like receptor 2; Belongs to the Toll-like receptor family. | Toll like receptor 6; Belongs to the Toll-like receptor family. | 0.918 |
TLR2 | TLR7 | ENSAPLP00000011131 | ENSAPLP00000003630 | Toll like receptor 2; Belongs to the Toll-like receptor family. | Toll like receptor 7; Belongs to the Toll-like receptor family. | 0.454 |
TLR3 | IFNG | ENSAPLP00000008663 | ENSAPLP00000012661 | Toll like receptor 3; Belongs to the Toll-like receptor family. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.680 |
TLR3 | TLR2 | ENSAPLP00000008663 | ENSAPLP00000011131 | Toll like receptor 3; Belongs to the Toll-like receptor family. | Toll like receptor 2; Belongs to the Toll-like receptor family. | 0.455 |
TLR3 | TLR4 | ENSAPLP00000008663 | ENSAPLP00000012401 | Toll like receptor 3; Belongs to the Toll-like receptor family. | Toll like receptor 4. | 0.658 |
TLR3 | TLR5 | ENSAPLP00000008663 | ENSAPLP00000000694 | Toll like receptor 3; Belongs to the Toll-like receptor family. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.490 |
TLR3 | TLR7 | ENSAPLP00000008663 | ENSAPLP00000003630 | Toll like receptor 3; Belongs to the Toll-like receptor family. | Toll like receptor 7; Belongs to the Toll-like receptor family. | 0.583 |
TLR4 | IFNG | ENSAPLP00000012401 | ENSAPLP00000012661 | Toll like receptor 4. | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. | 0.783 |
TLR4 | TLR2 | ENSAPLP00000012401 | ENSAPLP00000011131 | Toll like receptor 4. | Toll like receptor 2; Belongs to the Toll-like receptor family. | 0.841 |
TLR4 | TLR3 | ENSAPLP00000012401 | ENSAPLP00000008663 | Toll like receptor 4. | Toll like receptor 3; Belongs to the Toll-like receptor family. | 0.658 |
TLR4 | TLR5 | ENSAPLP00000012401 | ENSAPLP00000000694 | Toll like receptor 4. | TIR domain-containing protein; Belongs to the Toll-like receptor family. | 0.664 |