STRINGSTRING
SORD SORD TLR7 TLR7 TLR6 TLR6 HPRT1 HPRT1 IFNG IFNG TLR4 TLR4 TLR2 TLR2 TLR3 TLR3 TLR5 TLR5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SORDSorbitol dehydrogenase. (344 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)
TLR6Toll like receptor 6; Belongs to the Toll-like receptor family. (818 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (164 aa)
TLR4Toll like receptor 4. (843 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (914 aa)
TLR5TIR domain-containing protein; Belongs to the Toll-like receptor family. (878 aa)
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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