(13 nodes) (2019) Induction of Plasmodium-Specific Immune Responses Using Liposome-Based Vaccines. network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOX1	Aldehyde oxidase 1. (1336 aa)
	CD86	CD86 molecule. (341 aa)
	IL6	Uncharacterized protein. (350 aa)
	CD4	Ig-like domain-containing protein. (264 aa)
	CD40	TNFR-Cys domain-containing protein. (214 aa)
	IL10	Interleukin 10. (177 aa)
	U3J3X4_ANAPP	LRRCT domain-containing protein. (553 aa)
	TLR4	Toll like receptor 4. (843 aa)
	IL4	Uncharacterized protein. (136 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
	TLR-15	TIR domain-containing protein. (863 aa)
	FASLG	Fas ligand; Belongs to the tumor necrosis factor family. (237 aa)
	IL-17	Uncharacterized protein. (191 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD4	CD40	ENSAPLP00000018005	ENSAPLP00000016411	Ig-like domain-containing protein.	TNFR-Cys domain-containing protein.	0.938
CD4	CD86	ENSAPLP00000018005	ENSAPLP00000026026	Ig-like domain-containing protein.	CD86 molecule.	0.966
CD4	FASLG	ENSAPLP00000018005	ENSAPLP00000004898	Ig-like domain-containing protein.	Fas ligand; Belongs to the tumor necrosis factor family.	0.468
CD4	IL-17	ENSAPLP00000018005	ENSAPLP00000026822	Ig-like domain-containing protein.	Uncharacterized protein.	0.959
CD4	IL10	ENSAPLP00000018005	ENSAPLP00000015242	Ig-like domain-containing protein.	Interleukin 10.	0.959
CD4	IL4	ENSAPLP00000018005	ENSAPLP00000011598	Ig-like domain-containing protein.	Uncharacterized protein.	0.957
CD4	IL6	ENSAPLP00000018005	ENSAPLP00000020478	Ig-like domain-containing protein.	Uncharacterized protein.	0.961
CD4	TLR2	ENSAPLP00000018005	ENSAPLP00000011131	Ig-like domain-containing protein.	Toll like receptor 2; Belongs to the Toll-like receptor family.	0.577
CD4	TLR4	ENSAPLP00000018005	ENSAPLP00000012401	Ig-like domain-containing protein.	Toll like receptor 4.	0.837
CD4	U3J3X4_ANAPP	ENSAPLP00000018005	ENSAPLP00000014201	Ig-like domain-containing protein.	LRRCT domain-containing protein.	0.716
CD40	CD4	ENSAPLP00000016411	ENSAPLP00000018005	TNFR-Cys domain-containing protein.	Ig-like domain-containing protein.	0.938
CD40	CD86	ENSAPLP00000016411	ENSAPLP00000026026	TNFR-Cys domain-containing protein.	CD86 molecule.	0.965
CD40	FASLG	ENSAPLP00000016411	ENSAPLP00000004898	TNFR-Cys domain-containing protein.	Fas ligand; Belongs to the tumor necrosis factor family.	0.578
CD40	IL-17	ENSAPLP00000016411	ENSAPLP00000026822	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.739
CD40	IL10	ENSAPLP00000016411	ENSAPLP00000015242	TNFR-Cys domain-containing protein.	Interleukin 10.	0.815
CD40	IL4	ENSAPLP00000016411	ENSAPLP00000011598	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.924
CD40	IL6	ENSAPLP00000016411	ENSAPLP00000020478	TNFR-Cys domain-containing protein.	Uncharacterized protein.	0.823
CD40	TLR2	ENSAPLP00000016411	ENSAPLP00000011131	TNFR-Cys domain-containing protein.	Toll like receptor 2; Belongs to the Toll-like receptor family.	0.408
CD40	TLR4	ENSAPLP00000016411	ENSAPLP00000012401	TNFR-Cys domain-containing protein.	Toll like receptor 4.	0.787
CD86	CD4	ENSAPLP00000026026	ENSAPLP00000018005	CD86 molecule.	Ig-like domain-containing protein.	0.966