(19 nodes) (2020) The Role of Gamma Delta T Cells in Autoimmune Rheumatic Diseases. network (Anas platyrhynchos)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL22	Interleukin 22. (197 aa)
	EOMES	Eomesodermin. (746 aa)
	HPRT1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (225 aa)
	IL-17	Uncharacterized protein. (191 aa)
	CD86	CD86 molecule. (341 aa)
	ALB	Uncharacterized protein. (592 aa)
	IL23R	Uncharacterized protein. (549 aa)
	IL6	Uncharacterized protein. (350 aa)
	CD4	Ig-like domain-containing protein. (264 aa)
	CXCR5	C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	CD44	CD44 molecule (Indian blood group). (645 aa)
	IL10	Interleukin 10. (177 aa)
	IL4	Uncharacterized protein. (136 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (713 aa)
	PROCR	Uncharacterized protein. (687 aa)
	IL18	Interleukin-18. (197 aa)
	IL-2	Interleukin; Belongs to the IL-15/IL-21 family. (140 aa)
	ACAN	Aggrecan. (2145 aa)
	COL1A2	Collagen type I alpha 2 chain. (1363 aa)

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAN	ALB	ENSAPLP00000011051	ENSAPLP00000025530	Aggrecan.	Uncharacterized protein.	0.437
ACAN	CD44	ENSAPLP00000011051	ENSAPLP00000016839	Aggrecan.	CD44 molecule (Indian blood group).	0.640
ACAN	COL1A2	ENSAPLP00000011051	ENSAPLP00000032879	Aggrecan.	Collagen type I alpha 2 chain.	0.404
ALB	ACAN	ENSAPLP00000025530	ENSAPLP00000011051	Uncharacterized protein.	Aggrecan.	0.437
ALB	CD4	ENSAPLP00000025530	ENSAPLP00000018005	Uncharacterized protein.	Ig-like domain-containing protein.	0.792
ALB	CD44	ENSAPLP00000025530	ENSAPLP00000016839	Uncharacterized protein.	CD44 molecule (Indian blood group).	0.578
ALB	CD86	ENSAPLP00000025530	ENSAPLP00000026026	Uncharacterized protein.	CD86 molecule.	0.418
ALB	HPRT1	ENSAPLP00000025530	ENSAPLP00000028725	Uncharacterized protein.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.437
ALB	IL-17	ENSAPLP00000025530	ENSAPLP00000026822	Uncharacterized protein.	Uncharacterized protein.	0.595
ALB	IL-2	ENSAPLP00000025530	ENSAPLP00000006460	Uncharacterized protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.410
ALB	IL10	ENSAPLP00000025530	ENSAPLP00000015242	Uncharacterized protein.	Interleukin 10.	0.720
ALB	IL4	ENSAPLP00000025530	ENSAPLP00000011598	Uncharacterized protein.	Uncharacterized protein.	0.666
ALB	IL6	ENSAPLP00000025530	ENSAPLP00000020478	Uncharacterized protein.	Uncharacterized protein.	0.803
CD4	ALB	ENSAPLP00000018005	ENSAPLP00000025530	Ig-like domain-containing protein.	Uncharacterized protein.	0.792
CD4	CD44	ENSAPLP00000018005	ENSAPLP00000016839	Ig-like domain-containing protein.	CD44 molecule (Indian blood group).	0.951
CD4	CD86	ENSAPLP00000018005	ENSAPLP00000026026	Ig-like domain-containing protein.	CD86 molecule.	0.966
CD4	CXCR5	ENSAPLP00000018005	ENSAPLP00000000175	Ig-like domain-containing protein.	C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family.	0.870
CD4	EOMES	ENSAPLP00000018005	ENSAPLP00000030390	Ig-like domain-containing protein.	Eomesodermin.	0.611
CD4	HPRT1	ENSAPLP00000018005	ENSAPLP00000028725	Ig-like domain-containing protein.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.587
CD4	IL-17	ENSAPLP00000018005	ENSAPLP00000026822	Ig-like domain-containing protein.	Uncharacterized protein.	0.959